| Emerging and re-emerging warheads for targeted covalent inhibitors: applications in medicinal chemistry and chemical biology M Gehringer, SA Laufer Journal of medicinal chemistry 62 (12), 5673-5724, 2018 | 620 | 2018 |
| Inhibitors of c-Jun N-terminal kinases: an update P Koch, M Gehringer, SA Laufer Journal of medicinal chemistry 58 (1), 72-95, 2015 | 123 | 2015 |
| Selective JAK3 inhibitors with a covalent reversible binding mode targeting a new induced fit binding pocket M Forster, A Chaikuad, SM Bauer, J Holstein, MB Robers, CR Corona, ... Cell chemical biology 23 (11), 1335-1340, 2016 | 119 | 2016 |
| The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR R Bieri, N Scherr, MT Ruf, JP Dangy, P Gersbach, M Gehringer, ... ACS chemical biology 12 (5), 1297-1307, 2017 | 77 | 2017 |
| c-Jun N-terminal kinase inhibitors: a patent review (2010 – 2014) M Gehringer, F Muth, P Koch, SA Laufer Expert opinion on therapeutic patents 25 (8), 849-872, 2015 | 72 | 2015 |
| Development, Optimization, and Structure–Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine … M Forster, A Chaikuad, T Dimitrov, E Döring, J Holstein, BT Berger, ... Journal of Medicinal Chemistry 61 (12), 5350-5366, 2018 | 60 | 2018 |
| Silica-supported l-proline organocatalysts for asymmetric aldolisation A Zamboulis, NJ Rahier, M Gehringer, X Cattoën, G Niel, C Bied, ... Tetrahedron: Asymmetry 20 (24), 2880-2885, 2009 | 57 | 2009 |
| Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update L Hillebrand, XJ Liang, RAM Serafim, M Gehringer Journal of Medicinal Chemistry 67 (10), 7668-7758, 2024 | 42 | 2024 |
| Developing small‐molecule inhibitors of HECT‐type ubiquitin ligases for therapeutic applications: Challenges and opportunities D Chen, M Gehringer, S Lorenz ChemBioChem 19 (20), 2123-2135, 2018 | 39 | 2018 |
| The chemistry and biology of mycolactones M Gehringer, KH Altmann Beilstein journal of organic chemistry 13 (1), 1596-1660, 2017 | 39 | 2017 |
| Recent advances in JAK3 inhibition: Isoform selectivity by covalent cysteine targeting M Forster, M Gehringer, SA Laufer Bioorganic & medicinal chemistry letters 27 (18), 4229-4237, 2017 | 37 | 2017 |
| Design and synthesis of tricyclic JAK3 inhibitors with picomolar affinities as novel molecular probes M Gehringer, E Pfaffenrot, S Bauer, SA Laufer ChemMedChem 9 (2), 277-281, 2014 | 34 | 2014 |
| Covalent inhibitors: back on track? M Gehringer Future Medicinal Chemistry 12 (15), 1363-1368, 2020 | 32 | 2020 |
| Novel Hinge‐Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure–Activity Relationship Study on Tofacitinib Bioisosteres M Gehringer, M Forster, E Pfaffenrot, SM Bauer, SA Laufer ChemMedChem 9 (11), 2516-2527, 2014 | 31 | 2014 |
| Click Chemistry: Novel Applications in Cell Biology and Drug Discovery. M Gehringer, SA Laufer Angewandte Chemie (International ed. in English) 56 (49), 15504-15505, 2017 | 29 | 2017 |
| Solution-phase parallel synthesis of Ruxolitinib-derived Janus kinase inhibitors via copper-catalyzed Azide–Alkyne cycloaddition M Gehringer, M Forster, SA Laufer ACS Combinatorial Science 17 (1), 5-10, 2015 | 25 | 2015 |
| Nocathioamides, uncovered by a tunable metabologenomic approach, define a novel class of chimeric lanthipeptides H Saad, S Aziz, M Gehringer, M Kramer, J Straetener, A Berscheid, ... Angewandte Chemie International Edition 60 (30), 16472-16479, 2021 | 22 | 2021 |
| Gefitinib-tamoxifen hybrid ligands as potent agents against triple-negative breast cancer CM Abdelmalek, Z Hu, T Kronenberger, J Kublbeck, FJM Kinnen, ... Journal of Medicinal Chemistry 65 (6), 4616-4632, 2022 | 21 | 2022 |
| Development of the first covalent monopolar spindle kinase 1 (MPS1/TTK) Inhibitor RA M. Serafim, A da Silva Santiago, MP Schwalm, Z Hu, CV Dos Reis, ... Journal of Medicinal Chemistry 65 (4), 3173-3192, 2022 | 21 | 2022 |
| Discovery of a novel class of covalent dual inhibitors targeting the protein kinases BMX and BTK M Forster, XJ Liang, M Schröder, S Gerstenecker, A Chaikuad, S Knapp, ... International Journal of Molecular Sciences 21 (23), 9269, 2020 | 21 | 2020 |
