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Thomas D. Horvath
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Human-derived Bifidobacterium dentium modulates the mammalian serotonergic system and gut–brain axis
MA Engevik, B Luck, C Visuthranukul, FD Ihekweazu, AC Engevik, Z Shi, ...
Cellular and molecular gastroenterology and hepatology 11 (1), 221-248, 2021
1262021
Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia
WK Chan, TD Horvath, L Tan, T Link, KG Harutyunyan, MA Pontikos, ...
Molecular cancer therapeutics 18 (9), 1587-1592, 2019
822019
Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters
TD Horvath, FD Ihekweazu, SJ Haidacher, W Ruan, KA Engevik, R Fultz, ...
Iscience 25 (5), 2022
732022
Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation
MA Engevik, B Herrmann, W Ruan, AC Engevik, KA Engevik, ...
Gut Microbes 13 (1), 1902717, 2021
672021
Bacteroides ovatus promotes IL-22 production and reduces trinitrobenzene sulfonic acid–driven colonic inflammation
FD Ihekweazu, MA Engevik, W Ruan, Z Shi, R Fultz, KA Engevik, ...
The American journal of pathology 191 (4), 704-719, 2021
642021
Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium
B Luck, TD Horvath, KA Engevik, W Ruan, SJ Haidacher, KM Hoch, ...
Biomolecules 11 (8), 1091, 2021
412021
Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans
SL Stratton, TD Horvath, A Bogusiewicz, NI Matthews, CL Henrich, ...
The American journal of clinical nutrition 92 (6), 1399-1405, 2010
352010
Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS
TD Horvath, NI Matthews, SL Stratton, DM Mock, G Boysen
Analytical and bioanalytical chemistry 401, 2805-2810, 2011
332011
Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans
DM Mock, SL Stratton, TD Horvath, A Bogusiewicz, NI Matthews, ...
The Journal of nutrition 141 (11), 1925-1930, 2011
322011
Interrogation of the mammalian gut–brain axis using LC–MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models
TD Horvath, SJ Haidacher, MA Engevik, B Luck, W Ruan, F Ihekweazu, ...
Nature Protocols 18 (2), 490-529, 2023
302023
Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans
TD Horvath, SL Stratton, A Bogusiewicz, L Pack, J Moran, DM Mock
Analytical chemistry 82 (10), 4140-4144, 2010
302010
Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans
SL Stratton, TD Horvath, A Bogusiewicz, NI Matthews, CL Henrich, ...
The Journal of nutrition 141 (3), 353-358, 2011
292011
Addressing barriers in FAIR data practices for biomedical data
LD Hughes, G Tsueng, J DiGiovanna, TD Horvath, LV Rasmussen, ...
Scientific Data 10 (1), 98, 2023
252023
Unraveling the Metabolic Requirements of the Gut Commensal Bacteroides ovatus
R Fultz, T Ticer, FD Ihekweazu, TD Horvath, SJ Haidacher, KM Hoch, ...
Frontiers in Microbiology 12, 745469, 2021
232021
The metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal
MA Engevik, HA Danhof, A Hall, KA Engevik, TD Horvath, SJ Haidacher, ...
BMC microbiology 21 (1), 154, 2021
232021
Enteral activation of WR-2721 mediates radioprotection and improved survival from lethal fractionated radiation
JM Molkentine, TN Fujimoto, TD Horvath, AJ Grossberg, CJG Garcia, ...
Scientific reports 9 (1), 1949, 2019
222019
Quantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC− MS/MS as an indicator of biotin status in humans
TD Horvath, SL Stratton, A Bogusiewicz, SN Owen, DM Mock, JH Moran
Analytical chemistry 82 (22), 9543-9548, 2010
212010
Peptide vaccine formulation controls the duration of antigen presentation and magnitude of tumor-specific CD8+ T cell response
H Khong, A Volmari, M Sharma, Z Dai, CS Imo, Y Hailemichael, M Singh, ...
The Journal of Immunology 200 (10), 3464-3474, 2018
202018
Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters. iScience 25: 104158
TD Horvath, FD Ihekweazu, SJ Haidacher, W Ruan, KA Engevik, R Fultz, ...
192022
Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer
TD Horvath, WK Chan, MA Pontikos, LA Martin, D Du, L Tan, ...
Metabolites 9 (1), 10, 2019
182019
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