Gene prioritization through genomic data fusion S Aerts, D Lambrechts, S Maity, P Van Loo, B Coessens, F De Smet, ... Nature biotechnology 24 (5), 537-544, 2006 | 1146 | 2006 |
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization M Mazzone, D Dettori, RL de Oliveira, S Loges, T Schmidt, B Jonckx, ... Cell 136 (5), 839-851, 2009 | 944 | 2009 |
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system X Lu, F Le Noble, L Yuan, Q Jiang, B De Lafarge, D Sugiyama, C Bréant, ... Nature 432 (7014), 179-186, 2004 | 669 | 2004 |
Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way F De Smet, I Segura, K De Bock, PJ Hohensinner, P Carmeliet Arteriosclerosis, thrombosis, and vascular biology 29 (5), 639-649, 2009 | 528 | 2009 |
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization AR Pombo Antunes, I Scheyltjens, F Lodi, J Messiaen, A Antoranz, ... Nature neuroscience 24 (4), 595-610, 2021 | 439 | 2021 |
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer cell 37 (1), 21-36. e13, 2020 | 402 | 2020 |
FGF-dependent metabolic control of vascular development P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves, JS Fang, Y Xie, J Zhu, ... Nature 545 (7653), 224-228, 2017 | 357 | 2017 |
VEGF: A modifier of the del22q11 (DiGeorge) syndrome? I Stalmans, D Lambrechts, F De Smet, S Jansen, J Wang, S Maity, ... Nature medicine 9 (2), 173-182, 2003 | 345 | 2003 |
Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way P Carmeliet, F De Smet, S Loges, M Mazzone Nature reviews Clinical oncology 6 (6), 315-326, 2009 | 299 | 2009 |
Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ... Cell metabolism 31 (4), 862-877. e14, 2020 | 241 | 2020 |
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity L Vanderbeke, P Van Mol, Y Van Herck, F De Smet, S Humblet-Baron, ... Nature communications 12 (1), 4117, 2021 | 240 | 2021 |
Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties F Bono, F De Smet, C Herbert, K De Bock, M Georgiadou, P Fons, M Tjwa, ... Cancer cell 23 (4), 477-488, 2013 | 149 | 2013 |
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish I Geudens, R Herpers, K Hermans, I Segura, C Ruiz de Almodovar, ... Arteriosclerosis, thrombosis, and vascular biology 30 (9), 1695-1702, 2010 | 145 | 2010 |
Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling C Herbert, U Schieborr, K Saxena, J Juraszek, F De Smet, C Alcouffe, ... Cancer cell 23 (4), 489-501, 2013 | 137 | 2013 |
Role of neural guidance signals in blood vessel navigation M Autiero, F De Smet, F Claes, P Carmeliet Cardiovascular research 65 (3), 629-638, 2005 | 125 | 2005 |
Allosteric targeting of receptor tyrosine kinases F De Smet, A Christopoulos, P Carmeliet Nature biotechnology 32 (11), 1113-1120, 2014 | 102 | 2014 |
Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin S Kutschera, H Weber, A Weick, F De Smet, G Genove, M Takemoto, ... Arteriosclerosis, thrombosis, and vascular biology 31 (1), 151-159, 2011 | 85 | 2011 |
The neurovascular link in health and disease: an update I Segura, F De Smet, PJ Hohensinner, CR de Almodovar, P Carmeliet Trends in molecular medicine 15 (10), 439-451, 2009 | 79 | 2009 |
De novo design of a biologically active amyloid R Gallardo, M Ramakers, F De Smet, F Claes, L Khodaparast, ... Science 354 (6313), aah4949, 2016 | 76 | 2016 |
Structural hot spots for the solubility of globular proteins A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ... Nature communications 7 (1), 10816, 2016 | 72 | 2016 |