| The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein S Lu, Q Ye, D Singh, E Villa, DW Cleveland, KD Corbett Biorxiv, 2020 | 435 | 2020 |
| Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9 D Singh, SH Sternberg, J Fei, JA Doudna, T Ha Nature Communications 7, 2016 | 288 | 2016 |
| HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells H Yu, S Lu, K Gasior, D Singh, S Vazquez-Sanchez, O Tapia, D Toprani, ... Science 371 (6529), eabb4309, 2021 | 265 | 2021 |
| Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a) D Singh, J Mallon, A Poddar, Y Wang, R Tippana, O Yang, S Bailey, T Ha Proceedings of the National Academy of Sciences 115 (21), 5444-5449, 2018 | 193 | 2018 |
| An improved surface passivation method for single-molecule studies B Hua, KY Han, R Zhou, H Kim, X Shi, SC Abeysirigunawardena, A Jain, ... Nature methods 11 (12), 1233-1236, 2014 | 183 | 2014 |
| Protein stability and folding kinetics in the nucleus and endoplasmic reticulum of eucaryotic cells A Dhar, K Girdhar, D Singh, H Gelman, S Ebbinghaus, M Gruebele Biophysical journal 101 (2), 421-430, 2011 | 168 | 2011 |
| Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography FR Wagner, R Watanabe, R Schampers, D Singh, H Persoon, M Schaffer, ... Nature protocols 15 (6), 2041-2070, 2020 | 164 | 2020 |
| Determination of in vivo target search kinetics of regulatory noncoding RNA J Fei, D Singh, Q Zhang, S Park, D Balasubramanian, I Golding, ... Science 347 (6228), 1371-1374, 2015 | 161* | 2015 |
| Comprehensive structure and functional adaptations of the yeast nuclear pore complex CW Akey*, D Singh*, C Ouch*, I Echeverria*, I Nudelman, JM Varberg, ... Cell 185 (2), *Co-first authors, 2022 | 138 | 2022 |
| Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis D Singh, Y Wang, J Mallon, O Yang, J Fei, A Poddar, D Ceylan, S Bailey, ... Nature structural & molecular biology 25 (4), 347, 2018 | 133 | 2018 |
| Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding TH Ikenna Okafor*, Digvijay Singh*, Yanbo Wang*, Minhee Jung, Haobo Wang ... Nucleic Acids Research, *co-first author, 2019 | 41 | 2019 |
| Real-time observation of Cas9 postcatalytic domain motions Y Wang, J Mallon, H Wang, D Singh, M Hyun Jo, B Hua, S Bailey, T Ha Proceedings of the National Academy of Sciences 118 (2), e2010650118, 2021 | 31 | 2021 |
| HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science 371, eabb4309 H Yu, S Lu, K Gasior, D Singh, S Vazquez-Sanchez, O Tapia, D Toprani, ... | 22 | 2021 |
| The Molecular Architecture of the Nuclear Basket D Singh, N Soni, J Hutchings, I Echeverria, F Shaikh, M Duquette, ... BioRxiv, 2024 | 19 | 2024 |
| The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nat Commun 12: 502 S Lu, Q Ye, D Singh, Y Cao, JK Diedrich, JR Yates, E Villa, DW Cleveland, ... | 19 | 2021 |
| The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nat Commun. 2021; 12 (1): 502 S Lu, Q Ye, D Singh, Y Cao, JK Diedrich, JR Yates, E Villa, DW Cleveland, ... Epub 2021/01/23. https://doi. org/10.1038/s41467-020-20768-y PMID: 33479198, 2021 | 17 | 2021 |
| Understanding the molecular mechanisms of CRISPR toolbox using single molecule approaches D Singh, T Ha ACS Chemical Biology, 2018 | 17 | 2018 |
| A viral genome packaging ring-ATPase is a flexibly coordinated pentamer L Dai*, D Singh*, S Lu, VI Kottadiel, R Vafabakhsh, M Mahalingam, ... Nature communications 12 (1), *Co-first author, 2021 | 13 | 2021 |
| The single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays B Hua, Y Wang, S Park, KY Han, D Singh, JH Kim, W Cheng, T Ha Biochemistry 57 (10), 1572-1576, 2018 | 10 | 2018 |
| Effects of individual base-pairs on in vivo target search and destruction kinetics of small RNA A Poddar, MS Azam, T Kayikcioglu, M Bobrovskyy, J Zhang, X Ma, ... | 8* | 2020 |
Elizabeth VillaHHMI and Department of Molecular Biology, University of California San DiegoVerified email at ucsd.edu
