| Crystal structure of botulinum neurotoxin type A and implications for toxicity DB Lacy, W Tepp, AC Cohen, BR DasGupta, RC Stevens Nature structural biology 5 (10), 898-902, 1998 | 999 | 1998 |
| Clostridium difficile infection WK Smits, D Lyras, DB Lacy, MH Wilcox, EJ Kuijper Nature reviews Disease primers 2 (1), 1-20, 2016 | 983 | 2016 |
| Crystal structure of the anthrax lethal factor AD Pannifer, TY Wong, R Schwarzenbacher, M Renatus, C Petosa, ... Nature 414 (6860), 229-233, 2001 | 572 | 2001 |
| Sequence homology and structural analysis of the clostridial neurotoxins DB Lacy, RC Stevens Journal of molecular biology 291 (5), 1091-1104, 1999 | 411 | 1999 |
| The role of toxins in Clostridium difficile infection R Chandrasekaran, DB Lacy FEMS microbiology reviews 41 (6), 723-750, 2017 | 392 | 2017 |
| A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore BA Krantz, RA Melnyk, S Zhang, SJ Juris, DB Lacy, Z Wu, A Finkelstein, ... Science 309 (5735), 777-781, 2005 | 345 | 2005 |
| Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation DB Lacy, DJ Wigelsworth, RA Melnyk, SC Harrison, RJ Collier Proceedings of the National Academy of Sciences 101 (36), 13147-13151, 2004 | 292 | 2004 |
| The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen J Mogridge, K Cunningham, DB Lacy, M Mourez, RJ Collier Proceedings of the National Academy of Sciences 99 (10), 7045-7048, 2002 | 260 | 2002 |
| Toward a structural understanding of Clostridium difficile toxins A and B RN Pruitt, DB Lacy Frontiers in cellular and infection microbiology 2, 28, 2012 | 237 | 2012 |
| Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen K Cunningham, DB Lacy, J Mogridge, RJ Collier Proceedings of the National Academy of Sciences 99 (10), 7049-7053, 2002 | 235 | 2002 |
| Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen DJ Wigelsworth, BA Krantz, KA Christensen, DB Lacy, SJ Juris, RJ Collier Journal of Biological Chemistry 279 (22), 23349-23356, 2004 | 223 | 2004 |
| Cloning and variation of ground state intestinal stem cells X Wang, Y Yamamoto, LH Wilson, T Zhang, BE Howitt, MA Farrow, F Kern, ... Nature 522 (7555), 173-178, 2015 | 215 | 2015 |
| Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection T Reyes-Robles, F Alonzo, L Kozhaya, DB Lacy, D Unutmaz, VJ Torres Cell host & microbe 14 (4), 453-459, 2013 | 202 | 2013 |
| Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity ME LaFrance, MA Farrow, R Chandrasekaran, J Sheng, DH Rubin, ... Proceedings of the National Academy of Sciences 112 (22), 7073-7078, 2015 | 200 | 2015 |
| Structural organization of the functional domains of Clostridium difficile toxins A and B RN Pruitt, MG Chambers, KKS Ng, MD Ohi, DB Lacy Proceedings of the National Academy of Sciences 107 (30), 13467-13472, 2010 | 195 | 2010 |
| Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain KA Gangwer, DJ Mushrush, DL Stauff, B Spiller, MS McClain, TL Cover, ... Proceedings of the National Academy of Sciences 104 (41), 16293-16298, 2007 | 189 | 2007 |
| Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor DB Lacy, DJ Wigelsworth, HM Scobie, JAT Young, RJ Collier Proceedings of the National Academy of Sciences 101 (17), 6367-6372, 2004 | 172 | 2004 |
| Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism NM Chumbler, MA Farrow, LA Lapierre, JL Franklin, D Haslam, ... PLoS pathogens 8 (12), e1003072, 2012 | 151 | 2012 |
| Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex MA Farrow, NM Chumbler, LA Lapierre, JL Franklin, SA Rutherford, ... Proceedings of the National Academy of Sciences 110 (46), 18674-18679, 2013 | 141 | 2013 |
| Clostridioides difficile toxins: mechanisms of action and antitoxin therapeutics SL Kordus, AK Thomas, DB Lacy Nature Reviews Microbiology 20 (5), 285-298, 2022 | 135 | 2022 |