Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory GM Shankar, S Li, TH Mehta, A Garcia-Munoz, NE Shepardson, I Smith, ... Nature medicine 14 (8), 837-842, 2008 | 4588 | 2008 |
Complement and microglia mediate early synapse loss in Alzheimer mouse models S Hong, VF Beja-Glasser, BM Nfonoyim, A Frouin, S Li, S Ramakrishnan, ... Science 352 (6286), 712-716, 2016 | 2972 | 2016 |
Soluble oligomers of amyloid β protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake S Li, S Hong, NE Shepardson, DM Walsh, GM Shankar, D Selkoe Neuron 62 (6), 788-801, 2009 | 1210 | 2009 |
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors S Li, M Jin, T Koeglsperger, NE Shepardson, GM Shankar, DJ Selkoe Journal of Neuroscience 31 (18), 6627-6638, 2011 | 812 | 2011 |
Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty S Li, WK Cullen, R Anwyl, MJ Rowan Nature neuroscience 6 (5), 526-531, 2003 | 716 | 2003 |
Large soluble oligomers of amyloid β-protein from Alzheimer brain are far less neuroactive than the smaller oligomers to which they dissociate T Yang, S Li, H Xu, DM Walsh, DJ Selkoe Journal of Neuroscience 37 (1), 152-163, 2017 | 383 | 2017 |
Complement C3-deficient mice fail to display age-related hippocampal decline Q Shi, KJ Colodner, SB Matousek, K Merry, S Hong, JE Kenison, JL Frost, ... Journal of Neuroscience 35 (38), 13029-13042, 2015 | 381 | 2015 |
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions T Yu, Z Li, Z Jia, SJ Clapcote, C Liu, S Li, S Asrar, A Pao, R Chen, N Fan, ... Human molecular genetics 19 (14), 2780-2791, 2010 | 276 | 2010 |
Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment JA Arai, S Li, DM Hartley, LA Feig Journal of Neuroscience 29 (5), 1496-1502, 2009 | 264 | 2009 |
A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer’s brain S Li, DJ Selkoe Journal of neurochemistry 154 (6), 583-597, 2020 | 250 | 2020 |
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes S Hong, BL Ostaszewski, T Yang, TT O’Malley, M Jin, K Yanagisawa, S Li, ... Neuron 82 (2), 308-319, 2014 | 238 | 2014 |
Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression S Li, X Tian, DM Hartley, LA Feig Journal of Neuroscience 26 (6), 1721-1729, 2006 | 211 | 2006 |
Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers S Li, M Jin, D Zhang, T Yang, T Koeglsperger, H Fu, DJ Selkoe Neuron 77 (5), 929-941, 2013 | 209 | 2013 |
Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance M Lei, H Xu, Z Li, Z Wang, TT O'Malley, D Zhang, DM Walsh, P Xu, ... Neurobiology of disease 85, 111-121, 2016 | 163 | 2016 |
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice T Yu, C Liu, P Belichenko, SJ Clapcote, S Li, A Pao, A Kleschevnikov, ... Brain research 1366, 162-171, 2010 | 158 | 2010 |
Transglutaminase induces protofibril-like amyloid β-protein assemblies that are protease-resistant and inhibit long-term potentiation DM Hartley, C Zhao, AC Speier, GA Woodard, S Li, Z Li, T Walz Journal of Biological Chemistry 283 (24), 16790-16800, 2008 | 153 | 2008 |
Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP Z Wang, RJ Jackson, W Hong, WM Taylor, GT Corbett, A Moreno, W Liu, ... Journal of Neuroscience 37 (49), 11947-11966, 2017 | 146 | 2017 |
MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways R El Fatimy, S Li, Z Chen, T Mushannen, S Gongala, Z Wei, DT Balu, ... Acta Neuropathologica 136, 537-555, 2018 | 142 | 2018 |
Environmental enrichment potently prevents microglia-mediated neuroinflammation by human amyloid β-protein oligomers H Xu, E Gelyana, M Rajsombath, T Yang, S Li, D Selkoe Journal of Neuroscience 36 (35), 9041-9056, 2016 | 122 | 2016 |
Secreted amyloid β-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity AT Welzel, JE Maggio, GM Shankar, DE Walker, BL Ostaszewski, S Li, ... Biochemistry 53 (24), 3908-3921, 2014 | 112 | 2014 |