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Shaomin Li
Shaomin Li
Brigham and Women's Hospital and Harvard Medical School
Verified email at bwh.harvard.edu
Title
Cited by
Cited by
Year
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
GM Shankar, S Li, TH Mehta, A Garcia-Munoz, NE Shepardson, I Smith, ...
Nature medicine 14 (8), 837-842, 2008
45882008
Complement and microglia mediate early synapse loss in Alzheimer mouse models
S Hong, VF Beja-Glasser, BM Nfonoyim, A Frouin, S Li, S Ramakrishnan, ...
Science 352 (6286), 712-716, 2016
29722016
Soluble oligomers of amyloid β protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
S Li, S Hong, NE Shepardson, DM Walsh, GM Shankar, D Selkoe
Neuron 62 (6), 788-801, 2009
12102009
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
S Li, M Jin, T Koeglsperger, NE Shepardson, GM Shankar, DJ Selkoe
Journal of Neuroscience 31 (18), 6627-6638, 2011
8122011
Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty
S Li, WK Cullen, R Anwyl, MJ Rowan
Nature neuroscience 6 (5), 526-531, 2003
7162003
Large soluble oligomers of amyloid β-protein from Alzheimer brain are far less neuroactive than the smaller oligomers to which they dissociate
T Yang, S Li, H Xu, DM Walsh, DJ Selkoe
Journal of Neuroscience 37 (1), 152-163, 2017
3832017
Complement C3-deficient mice fail to display age-related hippocampal decline
Q Shi, KJ Colodner, SB Matousek, K Merry, S Hong, JE Kenison, JL Frost, ...
Journal of Neuroscience 35 (38), 13029-13042, 2015
3812015
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions
T Yu, Z Li, Z Jia, SJ Clapcote, C Liu, S Li, S Asrar, A Pao, R Chen, N Fan, ...
Human molecular genetics 19 (14), 2780-2791, 2010
2762010
Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment
JA Arai, S Li, DM Hartley, LA Feig
Journal of Neuroscience 29 (5), 1496-1502, 2009
2642009
A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer’s brain
S Li, DJ Selkoe
Journal of neurochemistry 154 (6), 583-597, 2020
2502020
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes
S Hong, BL Ostaszewski, T Yang, TT O’Malley, M Jin, K Yanagisawa, S Li, ...
Neuron 82 (2), 308-319, 2014
2382014
Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression
S Li, X Tian, DM Hartley, LA Feig
Journal of Neuroscience 26 (6), 1721-1729, 2006
2112006
Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers
S Li, M Jin, D Zhang, T Yang, T Koeglsperger, H Fu, DJ Selkoe
Neuron 77 (5), 929-941, 2013
2092013
Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance
M Lei, H Xu, Z Li, Z Wang, TT O'Malley, D Zhang, DM Walsh, P Xu, ...
Neurobiology of disease 85, 111-121, 2016
1632016
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice
T Yu, C Liu, P Belichenko, SJ Clapcote, S Li, A Pao, A Kleschevnikov, ...
Brain research 1366, 162-171, 2010
1582010
Transglutaminase induces protofibril-like amyloid β-protein assemblies that are protease-resistant and inhibit long-term potentiation
DM Hartley, C Zhao, AC Speier, GA Woodard, S Li, Z Li, T Walz
Journal of Biological Chemistry 283 (24), 16790-16800, 2008
1532008
Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP
Z Wang, RJ Jackson, W Hong, WM Taylor, GT Corbett, A Moreno, W Liu, ...
Journal of Neuroscience 37 (49), 11947-11966, 2017
1462017
MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways
R El Fatimy, S Li, Z Chen, T Mushannen, S Gongala, Z Wei, DT Balu, ...
Acta Neuropathologica 136, 537-555, 2018
1422018
Environmental enrichment potently prevents microglia-mediated neuroinflammation by human amyloid β-protein oligomers
H Xu, E Gelyana, M Rajsombath, T Yang, S Li, D Selkoe
Journal of Neuroscience 36 (35), 9041-9056, 2016
1222016
Secreted amyloid β-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity
AT Welzel, JE Maggio, GM Shankar, DE Walker, BL Ostaszewski, S Li, ...
Biochemistry 53 (24), 3908-3921, 2014
1122014
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