Riekelt Houtkooper

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Johan AuwerxProfessor at the EPFLVerified email at epfl.ch
Frederic VazClinical Biochemist, Amsterdam UMCVerified email at amsterdamumc.nl
Michel van Weeghel, PhDManager Core Facility Metabolomics, Amsterdam UMC, location AMCVerified email at amsterdamumc.nl
Laurent MouchiroudPhD in Biological SciencesVerified email at epfl.ch
Georges JanssensAssistant Professor, AMC, Amsterdam, The NetherlandsVerified email at amc.nl
schrauwen pDepartment of Nutrition and Movement Sciences, Maastricht UniversityVerified email at maastrichtuniversity.nl
Rob CI WüstVrije University Amsterdam, the NetherlandsVerified email at vu.nl
Dongryeol RyuGIST(Gwangju Institute of Science and Technology)Verified email at gist.ac.kr
Arwen W. GaoAssistant Professor, Amsterdam UMC - Location AMCVerified email at amsterdamumc.nl
Kristina SchoonjansProfessor at EPFLVerified email at epfl.ch
Rubén Zapata-PérezUniversidad Católica San Antonio de MurciaVerified email at ucam.edu
matthijs hesselinkuniversiteit maastrichtVerified email at maastrichtuniversity.nl
Marte MolenaarsPostdoctoral Fellow, NYU School of MedicineVerified email at nyulangone.org
Sander M. HoutenAssociate Professor, Icahn School of Medicine at Mount SinaiVerified email at mssm.edu
Yasmine Liupostdoc, EPFLVerified email at epfl.ch
Robert W WilliamsProfessor of Genetics, Genomics and Informatics, UTHSCVerified email at uthsc.edu
Sander KerstenDivision of Nutritional Sciences, Cornell UniversityVerified email at wur.nl
Evan G WilliamsAssociate Professor, LCSB, University of LuxembourgVerified email at uni.lu
HR WaterhamProfessor Functional Genetics of Metabolic Diseases at University of AmsterdamVerified email at amc.uva.nl
Peter BaiProfessor at the University of DebrecenVerified email at dote.hu

Riekelt Houtkooper

Professor of Translational Metabolism, Academic Medical Center (AMC), Amsterdam

Verified email at amc.nl

Mitochondria longevity aging inborn errors of metabolism NAD


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Sirtuins as regulators of metabolism and healthspan RH Houtkooper, E Pirinen, J Auwerx Nature reviews Molecular cell biology 13 (4), 225-238, 2012	2187	2012
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans S Timmers, E Konings, L Bilet, RH Houtkooper, T van de Weijer, ... Cell metabolism 14 (5), 612-622, 2011	1477	2011
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity C Cantó, RH Houtkooper, E Pirinen, DY Youn, MH Oosterveer, Y Cen, ... Cell metabolism 15 (6), 838-847, 2012	1343	2012
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantó, ... Cell 154 (2), 430-441, 2013	1278	2013
Mitonuclear protein imbalance as a conserved longevity mechanism RH Houtkooper, L Mouchiroud, D Ryu, N Moullan, E Katsyuba, G Knott, ... Nature 497 (7450), 451-457, 2013	1086	2013
The Secret Life of NAD⁺: An Old Metabolite Controlling New Metabolic Signaling Pathways RH Houtkooper, C Cantó, RJ Wanders, J Auwerx Endocrine reviews 31 (2), 194-223, 2010	1057	2010
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation P Bai, C Cantó, H Oudart, A Brunyánszki, Y Cen, C Thomas, H Yamamoto, ... Cell metabolism 13 (4), 461-468, 2011	914	2011
Metabolic flexibility as an adaptation to energy resources and requirements in health and disease RL Smith, MR Soeters, RCI Wüst, RH Houtkooper Endocrine reviews 39 (4), 489-517, 2018	616	2018
The metabolic footprint of aging in mice RH Houtkooper, C Argmann, SM Houten, C Cantó, EH Jeninga, ... Scientific reports 1 (1), 134, 2011	564	2011
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ... Cell reports 10 (10), 1681-1691, 2015	539	2015
Cardiolipin, the heart of mitochondrial metabolism RH Houtkooper, FM Vaz Cellular and Molecular Life Sciences 65, 2493-2506, 2008	528	2008
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells M Janiszewska, ML Suvà, N Riggi, RH Houtkooper, J Auwerx, ... Genes & development 26 (17), 1926-1944, 2012	486	2012
Pharmacological approaches to restore mitochondrial function PA Andreux, RH Houtkooper, J Auwerx Nature reviews Drug discovery 12 (6), 465-483, 2013	416	2013
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria F Gonzalvez, ZT Schug, RH Houtkooper, ED MacKenzie, DG Brooks, ... The Journal of cell biology 183 (4), 681-696, 2008	326	2008
Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle SJG Knottnerus, JC Bleeker, RCI Wüst, S Ferdinandusse, L IJlst, ... Reviews in Endocrine and Metabolic Disorders 19, 93-106, 2018	322	2018
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3 A Doddaballapur, KM Michalik, Y Manavski, T Lucas, RH Houtkooper, ... Arteriosclerosis, thrombosis, and vascular biology 35 (1), 137-145, 2015	311	2015
Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes E Lachmandas, L Boutens, JM Ratter, A Hijmans, GJ Hooiveld, ... Nature microbiology 2 (3), 1-10, 2016	304	2016
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome D Acehan, F Vaz, RH Houtkooper, J James, V Moore, C Tokunaga, ... Journal of biological chemistry 286 (2), 899-908, 2011	297	2011
Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease YJ Liu, RL McIntyre, GE Janssens, RH Houtkooper Mechanisms of ageing and development 186, 111212, 2020	284	2020
Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood A Zeharia, A Shaag, RH Houtkooper, T Hindi, P de Lonlay, G Erez, ... The American Journal of Human Genetics 83 (4), 489-494, 2008	266	2008

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