| RNA-guided gene activation by CRISPR-Cas9–based transcription factors P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, ... Nature methods 10 (10), 973-976, 2013 | 1731 | 2013 |
| Electrohydrodynamics: A facile technique to fabricate drug delivery systems S Chakraborty, IC Liao, A Adler, KW Leong Advanced drug delivery reviews 61 (12), 1043-1054, 2009 | 697 | 2009 |
| Targeted epigenetic remodeling of endogenous loci by CRISPR/Cas9-based transcriptional activators directly converts fibroblasts to neuronal cells JB Black, AF Adler, HG Wang, AM D’Ippolito, HA Hutchinson, TE Reddy, ... Cell stem cell 19 (3), 406-414, 2016 | 251 | 2016 |
| Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery AF Adler, KW Leong Nano today 5 (6), 553-569, 2010 | 208 | 2010 |
| Generation and post-injury integration of human spinal cord neural stem cells H Kumamaru, K Kadoya, AF Adler, Y Takashima, L Graham, G Coppola, ... Nature methods 15 (9), 723-731, 2018 | 184 | 2018 |
| Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming N Christoforou, M Chellappan, AF Adler, RD Kirkton, T Wu, RC Addis, ... PloS one 8 (5), e63577, 2013 | 172 | 2013 |
| Dynamic topographical control of mesenchymal stem cells by culture on responsive poly (ε-caprolactone) surfaces DM Le, K Kulangara, AF Adler, KW Leong, VS Ashby Advanced Materials (Deerfield Beach, Fla.) 23 (29), 3278, 2011 | 166 | 2011 |
| Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts JN Dulin, AF Adler, H Kumamaru, GHD Poplawski, C Lee-Kubli, H Strobl, ... Nature communications 9 (1), 84, 2018 | 128 | 2018 |
| Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... Nature communications 11 (1), 2434, 2020 | 111 | 2020 |
| The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons K Kulangara, AF Adler, H Wang, M Chellappan, E Hammett, R Yasuda, ... Biomaterials 35 (20), 5327-5336, 2014 | 98 | 2014 |
| hESC-derived dopaminergic transplants integrate into basal ganglia circuitry in a preclinical model of Parkinson’s disease AF Adler, T Cardoso, S Nolbrant, B Mattsson, DB Hoban, U Jarl, ... Cell reports 28 (13), 3462-3473. e5, 2019 | 93 | 2019 |
| Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells AF Adler, CL Grigsby, K Kulangara, H Wang, R Yasuda, KW Leong Molecular therapy Nucleic acids 1, 2012 | 77 | 2012 |
| Comprehensive monosynaptic rabies virus mapping of host connectivity with neural progenitor grafts after spinal cord injury AF Adler, C Lee-Kubli, H Kumamaru, K Kadoya, MH Tuszynski Stem cell reports 8 (6), 1525-1533, 2017 | 73 | 2017 |
| Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of Parkinsonian rats T Cardoso, AF Adler, B Mattsson, DB Hoban, S Nolbrant, JN Wahlestedt, ... Journal of Comparative Neurology 526 (13), 2133-2146, 2018 | 67 | 2018 |
| Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PD A Kirkeby, J Nelander, DB Hoban, N Rogelius, H Bjartmarz, P Storm, ... Cell Stem Cell 30 (10), 1299-1314. e9, 2023 | 59 | 2023 |
| Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers D Gallego-Perez, JJ Otero, C Czeisler, J Ma, C Ortiz, P Gygli, ... Nanomedicine: Nanotechnology, Biology and Medicine 12 (2), 399-409, 2016 | 57 | 2016 |
| High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts AF Adler, AT Speidel, N Christoforou, K Kolind, M Foss, KW Leong Biomaterials 32 (14), 3611-3619, 2011 | 53 | 2011 |
| Core transcription factors, microRNAs, and small molecules drive transdifferentiation of human fibroblasts towards the cardiac cell lineage N Christoforou, S Chakraborty, RD Kirkton, AF Adler, RC Addis, ... Scientific reports 7 (1), 40285, 2017 | 50 | 2017 |
| Patterned transgene expression in multiple-channel bridges after spinal cord injury L De Laporte, A Huang, MM Ducommun, ML Zelivyanska, MO Aviles, ... Acta biomaterialia 6 (8), 2889-2897, 2010 | 49 | 2010 |
| High throughput cell-based screening of biodegradable polyanhydride libraries AF Adler, LK Petersen, JH Wilson, MP Torres, JB Thorstenson, ... Combinatorial chemistry & high throughput screening 12 (7), 634-645, 2009 | 45 | 2009 |
Kam LeongBiomedical Engineering, Columbia UniversityVerified email at columbia.edu