The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling PP Hsu, SA Kang, J Rameseder, Y Zhang, KA Ottina, D Lim, TR Peterson, ... science 332 (6035), 1317-1322, 2011 | 1249 | 2011 |
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery L Macůrek, A Lindqvist, D Lim, MA Lampson, R Klompmaker, R Freire, ... Nature 455 (7209), 119-123, 2008 | 817 | 2008 |
Structural basis for the β lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus D Lim, NCJ Strynadka Nature structural biology 9 (11), 870-876, 2002 | 748 | 2002 |
Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A MG Bertero, RA Rothery, M Palak, C Hou, D Lim, F Blasco, JH Weiner, ... Nature structural & molecular biology 10 (9), 681-687, 2003 | 566 | 2003 |
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation IA Manke, A Nguyen, D Lim, MQ Stewart, AEH Elia, MB Yaffe Molecular cell 17 (1), 37-48, 2005 | 525 | 2005 |
mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin SA Kang, ME Pacold, CL Cervantes, D Lim, HJ Lou, K Ottina, NS Gray, ... Science 341 (6144), 1236566, 2013 | 507 | 2013 |
A Ca2+ switch aligns the active site of calpain T Moldoveanu, CM Hosfield, D Lim, JS Elce, Z Jia, PL Davies Cell 108 (5), 649-660, 2002 | 438 | 2002 |
Structure and function of Polo-like kinases DM Lowery, D Lim, MB Yaffe Oncogene 24 (2), 248-259, 2005 | 411 | 2005 |
Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis AL Lovering, LH De Castro, D Lim, NCJ Strynadka Science 315 (5817), 1402-1405, 2007 | 380 | 2007 |
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog CPC Chiu, AG Watts, LL Lairson, M Gilbert, D Lim, WW Wakarchuk, ... Nature structural & molecular biology 11 (2), 163-170, 2004 | 290 | 2004 |
Proteomic screen defines the Polo‐box domain interactome and identifies Rock2 as a Plk1 substrate DM Lowery, KR Clauser, M Hjerrild, D Lim, J Alexander, K Kishi, SE Ong, ... The EMBO journal 26 (9), 2262-2273, 2007 | 284 | 2007 |
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, ... PLoS pathogens 8 (6), e1002784, 2012 | 254 | 2012 |
Crystal structures of Escherichia coli phytase and its complex with phytate D Lim, S Golovan, CW Forsberg, Z Jia nature structural biology 7 (2), 108-113, 2000 | 229 | 2000 |
An independently validated nomogram for individualized estimation of survival among patients with newly diagnosed glioblastoma: NRG Oncology RTOG 0525 and 0825 H Gittleman, D Lim, MW Kattan, A Chakravarti, MR Gilbert, AB Lassman, ... Neuro-oncology 19 (5), 669-677, 2017 | 205 | 2017 |
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1 SM Yun, T Moulaei, D Lim, JK Bang, JE Park, SR Shenoy, FA Liu, ... Nature structural & molecular biology 16 (8), 876-882, 2009 | 195 | 2009 |
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling J Alexander, D Lim, BA Joughin, B Hegemann, JRA Hutchins, ... Science signaling 4 (179), ra42-ra42, 2011 | 193 | 2011 |
Structural and biochemical characterization of the type III secretion chaperones CesT and SigE Y Luo, MG Bertero, EA Frey, RA Pfuetzner, MR Wenk, L Creagh, ... Nature structural biology 8 (12), 1031-1036, 2001 | 176 | 2001 |
Crystal structure of the MexR repressor of themexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa D Lim, K Poole, NCJ Strynadka Journal of biological chemistry 277 (32), 29253-29259, 2002 | 168 | 2002 |
Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes JM Rock, D Lim, L Stach, RW Ogrodowicz, JM Keck, MH Jones, ... Science 340 (6134), 871-875, 2013 | 128 | 2013 |
Crystal structure and kinetic analysis of β-lactamase inhibitor protein-II in complex with TEM-1 β-lactamase D Lim, HU Park, L De Castro, SG Kang, HS Lee, S Jensen, KJ Lee, ... Nature structural biology 8 (10), 848-852, 2001 | 121 | 2001 |