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Andrew M Kidger
Andrew M Kidger
Postdoctoral Research Scientist, Babraham Institute
Verified email at babraham.ac.uk
Title
Cited by
Cited by
Year
The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)
AM Kidger, SM Keyse
Seminars in cell & developmental biology 50, 125-132, 2016
2662016
Dual-specificity MAP kinase phosphatases in health and disease
OM Seternes, AM Kidger, SM Keyse
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (1), 124-143, 2019
1432019
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
AM Kidger, J Sipthorp, SJ Cook
Pharmacology & therapeutics 187, 45-60, 2018
1302018
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling
AM Kidger, LK Rushworth, J Stellzig, J Davidson, CJ Bryant, C Bayley, ...
Proceedings of the National Academy of Sciences 114 (3), E317-E326, 2017
972017
An mTORC1-to-CDK1 switch maintains autophagy suppression during mitosis
RI Odle, SA Walker, D Oxley, AM Kidger, K Balmanno, R Gilley, ...
Molecular cell 77 (2), 228-240. e7, 2020
942020
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression
LK Rushworth, AM Kidger, L Delavaine, G Stewart, S Van Schelven, ...
Proceedings of the National Academy of Sciences 111 (51), 18267-18272, 2014
822014
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors
PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ...
Nature communications 11 (1), 1383, 2020
502020
Dual-mechanism ERK1/2 inhibitors exploit a distinct binding mode to block phosphorylation and nuclear accumulation of ERK1/2
AM Kidger, JM Munck, HK Saini, K Balmanno, E Minihane, A Courtin, ...
Molecular cancer therapeutics 19 (2), 525-539, 2020
262020
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
AM Kidger, MK Saville, LK Rushworth, J Davidson, J Stellzig, M Ono, ...
Oncogene 41 (20), 2811-2823, 2022
162022
Visualization of endogenous ERK1/2 in cells with a bioorthogonal covalent probe
J Sipthorp, H Lebraud, R Gilley, AM Kidger, H Okkenhaug, M Saba-El-Leil, ...
Bioconjugate Chemistry 28 (6), 1677-1683, 2017
122017
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
BS Ferguson, SA Wennersten, KM Demos-Davies, M Rubino, ...
American Journal of Physiology-Heart and Circulatory Physiology 321 (2 …, 2021
102021
ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1
K Balmanno, AM Kidger, DP Byrne, MJ Sale, N Nassman, PA Eyers, ...
Biochemical Journal 480 (9), 587-605, 2023
72023
Visualizing and quantitating the spatiotemporal regulation of Ras/ERK signaling by dual-specificity mitogen-activated protein phosphatases (MKPs)
CJ Caunt, AM Kidger, SM Keyse
Protein Tyrosine Phosphatases: Methods and Protocols, 197-215, 2016
62016
De‐RSKing ERK–regulation of ERK1/2‐RSK dissociation by phosphorylation within a disordered motif
AM Kidger, SJ Cook
The FEBS journal 285 (1), 42-45, 2018
52018
Dual-Specificity Map Kinase (MAPK) Phosphatases (MKPs) and Their Involvement in Cancer
AM Kidger, SM Keyse
Protein Tyrosine Phosphatases in Cancer, 201-231, 2016
12016
RAF inhibitors activate the integrated stress response by direct activation of GCN2
R Gilley, AM Kidger, G Neill, P Severson, DP Byrne, NS Kenneth, ...
bioRxiv, 2024.08. 15.607884, 2024
2024
Signaling and Stress Response: DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
BS Ferguson, SA Wennersten, KM Demos-Davies, M Rubino, ...
American Journal of Physiology-Heart and Circulatory Physiology 321 (2), H382, 2021
2021
The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases
AM Kidger
University of Dundee, 2016
2016
Submission PDF
A Kidgera, L Rushwortha, J Stellziga, J Davidsona, C Bryantb, ...
PNAS 67, 68, 0
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