The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs) AM Kidger, SM Keyse Seminars in cell & developmental biology 50, 125-132, 2016 | 266 | 2016 |
Dual-specificity MAP kinase phosphatases in health and disease OM Seternes, AM Kidger, SM Keyse Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (1), 124-143, 2019 | 143 | 2019 |
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway AM Kidger, J Sipthorp, SJ Cook Pharmacology & therapeutics 187, 45-60, 2018 | 130 | 2018 |
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling AM Kidger, LK Rushworth, J Stellzig, J Davidson, CJ Bryant, C Bayley, ... Proceedings of the National Academy of Sciences 114 (3), E317-E326, 2017 | 97 | 2017 |
An mTORC1-to-CDK1 switch maintains autophagy suppression during mitosis RI Odle, SA Walker, D Oxley, AM Kidger, K Balmanno, R Gilley, ... Molecular cell 77 (2), 228-240. e7, 2020 | 94 | 2020 |
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression LK Rushworth, AM Kidger, L Delavaine, G Stewart, S Van Schelven, ... Proceedings of the National Academy of Sciences 111 (51), 18267-18272, 2014 | 82 | 2014 |
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ... Nature communications 11 (1), 1383, 2020 | 50 | 2020 |
Dual-mechanism ERK1/2 inhibitors exploit a distinct binding mode to block phosphorylation and nuclear accumulation of ERK1/2 AM Kidger, JM Munck, HK Saini, K Balmanno, E Minihane, A Courtin, ... Molecular cancer therapeutics 19 (2), 525-539, 2020 | 26 | 2020 |
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6 AM Kidger, MK Saville, LK Rushworth, J Davidson, J Stellzig, M Ono, ... Oncogene 41 (20), 2811-2823, 2022 | 16 | 2022 |
Visualization of endogenous ERK1/2 in cells with a bioorthogonal covalent probe J Sipthorp, H Lebraud, R Gilley, AM Kidger, H Okkenhaug, M Saba-El-Leil, ... Bioconjugate Chemistry 28 (6), 1677-1683, 2017 | 12 | 2017 |
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy BS Ferguson, SA Wennersten, KM Demos-Davies, M Rubino, ... American Journal of Physiology-Heart and Circulatory Physiology 321 (2 …, 2021 | 10 | 2021 |
ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1 K Balmanno, AM Kidger, DP Byrne, MJ Sale, N Nassman, PA Eyers, ... Biochemical Journal 480 (9), 587-605, 2023 | 7 | 2023 |
Visualizing and quantitating the spatiotemporal regulation of Ras/ERK signaling by dual-specificity mitogen-activated protein phosphatases (MKPs) CJ Caunt, AM Kidger, SM Keyse Protein Tyrosine Phosphatases: Methods and Protocols, 197-215, 2016 | 6 | 2016 |
De‐RSKing ERK–regulation of ERK1/2‐RSK dissociation by phosphorylation within a disordered motif AM Kidger, SJ Cook The FEBS journal 285 (1), 42-45, 2018 | 5 | 2018 |
Dual-Specificity Map Kinase (MAPK) Phosphatases (MKPs) and Their Involvement in Cancer AM Kidger, SM Keyse Protein Tyrosine Phosphatases in Cancer, 201-231, 2016 | 1 | 2016 |
RAF inhibitors activate the integrated stress response by direct activation of GCN2 R Gilley, AM Kidger, G Neill, P Severson, DP Byrne, NS Kenneth, ... bioRxiv, 2024.08. 15.607884, 2024 | | 2024 |
Signaling and Stress Response: DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy BS Ferguson, SA Wennersten, KM Demos-Davies, M Rubino, ... American Journal of Physiology-Heart and Circulatory Physiology 321 (2), H382, 2021 | | 2021 |
The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases AM Kidger University of Dundee, 2016 | | 2016 |
Submission PDF A Kidgera, L Rushwortha, J Stellziga, J Davidsona, C Bryantb, ... PNAS 67, 68, 0 | | |