Aaron N. Brooks

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Nitin BaligaProfessorVerified email at systemsbiology.org
Lars SteinmetzProfessor of Genetics, Stanford UniversityVerified email at stanford.edu
Karlyn Beer, MS, PhDARPA-HVerified email at arpa-h.gov
Serdar TurkarslanInstitute for Systems BiologyVerified email at systemsbiology.org
Leslie MitchellPostdoctoral Felllow, New York UniversityVerified email at nyumc.org
Jef D. BoekeNYU Langone HealthVerified email at nyulangone.org
Fred C. BoogerdAmsterdam Institute for Life and Environment, VU University , Section Systems BiologyVerified email at vu.nl
Alexey KolodkinLuxembourg Centre for Systems Biomedicine (Luxembourg)Verified email at uni.lu
Vangelis SimeonidisSenior Project Manager, PATHVerified email at path.org
Hans WesterhoffUniversity of Amsterdam, VU University Amsterdam, University of ManchesterVerified email at manchester.ac.uk
Rodolfo García ContrerasDepartamento de Microbiología y Parasitología Facultad de Medicina UNAMVerified email at bq.unam.mx
Christopher PlaisierAssistant Professor, School for Biological and Health Systems EngineeringVerified email at asu.edu
Mario L Arrieta-OrtizInstitute for Systems BiologyVerified email at nyu.edu
Fei HeAssociate Professor, Coventry UniversityVerified email at coventry.ac.uk
Sriram ChandrasekaranAssociate Professor of Biomedical Engineering at University of Michigan, Ann ArborVerified email at umich.edu
Antoine AllardUniversité LavalVerified email at phy.ulaval.ca
Diego Martinez SalvanhaPhD Student, University of Sao PauloVerified email at usp.br
Roy S. K. WalkerMacquarie UniversityVerified email at mq.edu.au
Giovanni StracquadanioPersonal Chair in Engineering Biology, The University of EdinburghVerified email at ed.ac.uk
Yu ZhaoNYU Langone HealthVerified email at nyulangone.org

Aaron N. Brooks

Principal Scientist @ Generate:Biomedicines

Verified email at generatebiomedicines.com - Homepage

systems biology synthetic biology genetics complex systems


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Adaptation of cells to new environments AN Brooks, S Turkarslan, KD Beer, F Yin Lo, NS Baliga Wiley Interdisciplinary Reviews: Systems Biology and Medicine 3 (5), 544-561, 2011	238	2011
Macromolecular networks and intelligence in microorganisms HV Westerhoff, AN Brooks, E Simeonidis, R García-Contreras, F He, ... Frontiers in microbiology 5, 379, 2014	102	2014
A system‐level model for the microbial regulatory genome AN Brooks, DJ Reiss, A Allard, WJ Wu, DM Salvanha, CL Plaisier, ... Molecular systems biology 10 (7), 740, 2014	73	2014
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ... Cell 186 (24), 5220-5236. e16, 2023	69	2023
Data-driven integration of genome-scale regulatory and metabolic network models S Imam, S Schäuble, AN Brooks, NS Baliga, ND Price Frontiers in microbiology 6, 409, 2015	64	2015
Design, construction, and functional characterization of a tRNA neochromosome in yeast D Schindler, RSK Walker, S Jiang, AN Brooks, Y Wang, CA Müller, ... Cell 186 (24), 5237-5253. e22, 2023	49	2023
Transcriptional neighborhoods regulate transcript isoform lengths and expression levels AN Brooks, AL Hughes, S Clauder-Münster, LA Mitchell, JD Boeke, ... Science 375 (6584), 1000-1005, 2022	34	2022
Deep mutational scanning of essential bacterial proteins can guide antibiotic development L Dewachter, AN Brooks, K Noon, C Cialek, A Clark-ElSayed, T Schalck, ... nature communications 14 (1), 241, 2023	29	2023
Evolution of context dependent regulation by expansion of feast/famine regulatory proteins CL Plaisier, FY Lo, J Ashworth, AN Brooks, KD Beer, A Kaur, M Pan, ... BMC systems biology 8, 1-14, 2014	28	2014
Evolthon: A community endeavor to evolve lab evolution S Kaminski Strauss, D Schirman, G Jona, AN Brooks, AM Kunjapur, ... PLoS biology 17 (3), e3000182, 2019	17	2019
MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance EJR Peterson, AN Brooks, DJ Reiss, A Kaur, J Do, M Pan, WJ Wu, ... Cell Reports 42 (8), 2023	13	2023
Disrupting the ArcA regulatory network amplifies the fitness cost of tetracycline resistance in Escherichia coli ML Arrieta-Ortiz, M Pan, A Kaur, E Pepper-Tunick, V Srinivas, A Dash, ... Msystems 8 (1), e00904-22, 2023	11	2023
MtrA regulation of essential peptidoglycan cleavage in Mycobacterium tuberculosis during infection EJR Peterson, AN Brooks, DJ Reiss, A Kaur, WJ Wu, R Morrison, ... BioRxiv, 2021.02. 25.432019, 2021	5	2021
Methods for isolating and/or obtaining captured polynucleotide fragments J Cosimo, SA JOHANSSON, AN Brooks, A Hughes, LM Steinmetz US Patent App. 18/501,530, 2024		2024
Automated and Computational Approaches to Metabolic Engineering G Sriram, A Brooks SIMB 2023 Annual Meeting, 2023		2023
Genome-wide rationally-designed mutations leading to enhanced cellobiohydrolase i production in s. cerevisiae E Abbate, K Krouse, A Brooks, T Shepherd, N Krishnamurthy WO Patent WO2023028521A1, 2023		2023
System and method for gene editing cassette design A Halweg-Edwards, J Shorenstein, A Garst, C Struble, M Gander, J Kim, ... US Patent US20220246235A1, 2022		2022
SYGNALing a Red Light for Glioblastoma AN Brooks, WF Mueller, LM Steinmetz Cell Systems 3 (2), 118-120, 2016		2016
Data-driven integration of genome-scale regulatory and metabolic network models AN Brooks, NS Baliga		2015
Data-driven inference of dynamic transcriptional regulatory mechanisms in prokaryotes: a systems perspective AN Brooks		2014

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