A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene J Luo, MJ Emanuele, D Li, CJ Creighton, MR Schlabach, TF Westbrook, ... Cell 137 (5), 835-848, 2009 | 1206 | 2009 |
Global identification of modular cullin-RING ligase substrates MJ Emanuele, AEH Elia, Q Xu, CR Thoma, L Izhar, Y Leng, A Guo, ... Cell 147 (2), 459-474, 2011 | 460 | 2011 |
Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome HW Wang, ME Putt, MJ Emanuele, DB Shin, E Glatstein, AG Yodh, ... Cancer research 64 (20), 7553-7561, 2004 | 215 | 2004 |
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly MJ Emanuele, W Lan, M Jwa, SA Miller, CSM Chan, PT Stukenberg The Journal of cell biology 181 (2), 241-254, 2008 | 196 | 2008 |
A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells T Ly, Y Ahmad, A Shlien, D Soroka, A Mills, MJ Emanuele, MR Stratton, ... Elife 3, e01630, 2014 | 143 | 2014 |
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate MJ Emanuele, A Ciccia, AEH Elia, SJ Elledge Proceedings of the National Academy of Sciences 108 (24), 9845-9850, 2011 | 122 | 2011 |
Dissenting degradation: Deubiquitinases in cell cycle and cancer T Bonacci, MJ Emanuele Seminars in cancer biology 67, 145-158, 2020 | 97 | 2020 |
APC/C and SCFcyclin F constitute a reciprocal feedback circuit controlling S-phase entry R Choudhury, T Bonacci, A Arceci, D Lahiri, CA Mills, JL Kernan, ... Cell reports 16 (12), 3359-3372, 2016 | 92 | 2016 |
Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore MJ Emanuele, ML McCleland, DL Satinover, PT Stukenberg Molecular biology of the cell 16 (10), 4882-4892, 2005 | 92 | 2005 |
FOXM1 deubiquitination by USP21 regulates cell cycle progression and paclitaxel sensitivity in basal-like breast cancer A Arceci, T Bonacci, X Wang, K Stewart, JS Damrauer, KA Hoadley, ... Cell reports 26 (11), 3076-3086. e6, 2019 | 86 | 2019 |
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin VV Vorozhko, MJ Emanuele, MJ Kallio, PT Stukenberg, GJ Gorbsky Chromosoma 117, 169-179, 2008 | 82 | 2008 |
Cezanne/OTUD 7B is a cell cycle‐regulated deubiquitinase that antagonizes the degradation of APC/C substrates T Bonacci, A Suzuki, GD Grant, N Stanley, JG Cook, NG Brown, ... The EMBO journal 37 (16), e98701, 2018 | 81 | 2018 |
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome JY Jason, SR Paranjape, MP Walker, R Choudhury, JM Wolter, G Fragola, ... Journal of Biological Chemistry 292 (30), 12503-12515, 2017 | 78 | 2017 |
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells MT Weng, JH Lee, SC Wei, Q Li, S Shahamatdar, D Hsu, AJ Schetter, ... Proceedings of the National Academy of Sciences 109 (52), E3659-E3667, 2012 | 77 | 2012 |
Who guards the guardian? Mechanisms that restrain APC/C during the cell cycle J Kernan, T Bonacci, MJ Emanuele Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (12), 1924-1933, 2018 | 76 | 2018 |
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients TM Busch, SM Hahn, EP Wileyto, CJ Koch, DL Fraker, P Zhang, M Putt, ... Clinical cancer research 10 (14), 4630-4638, 2004 | 74 | 2004 |
Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer DR Blake, AV Vaseva, RG Hodge, MKP Kline, TSK Gilbert, V Tyagi, ... Science signaling 12 (590), eaav7259, 2019 | 67 | 2019 |
Complex cartography: regulation of E2F transcription factors by cyclin F and ubiquitin MJ Emanuele, TP Enrico, RD Mouery, D Wasserman, S Nachum, A Tzur Trends in cell biology 30 (8), 640-652, 2020 | 63 | 2020 |
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment MJ Emanuele, PT Stukenberg Cell 130 (5), 893-905, 2007 | 58 | 2007 |
The E3 ubiquitin ligase SCF (Cyclin F) transmits AKT signaling to the cell-cycle machinery R Choudhury, T Bonacci, X Wang, A Truong, A Arceci, Y Zhang, CA Mills, ... Cell reports 20 (13), 3212-3222, 2017 | 56 | 2017 |