Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling CM Madl, BL LeSavage, RE Dewi, CB Dinh, RS Stowers, M Khariton, ... Nature materials 16 (12), 1233-1242, 2017 | 403 | 2017 |
Next-generation cancer organoids BL LeSavage, RA Suhar, N Broguiere, MP Lutolf, SC Heilshorn Nature materials 21 (2), 143-159, 2022 | 348 | 2022 |
Matrix remodeling enhances the differentiation capacity of neural progenitor cells in 3D hydrogels CM Madl, BL LeSavage, RE Dewi, KJ Lampe, SC Heilshorn Advanced Science 6 (4), 1801716, 2019 | 106 | 2019 |
Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling J Qian, BL LeSavage, KM Hubka, C Ma, S Natarajan, JT Eggold, Y Xiao, ... The Journal of Clinical Investigation 131 (16), 2021 | 86 | 2021 |
Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids DR Hunt, KC Klett, S Mascharak, HY Wang, D Gong, J Lou, X Li, PC Cai, ... Advanced Science, 2004705, 2021 | 66 | 2021 |
Bioprinting cell-and spheroid-laden protein-engineered hydrogels as tissue-on-chip platforms DF Duarte Campos, CD Lindsay, JG Roth, BL LeSavage, AJ Seymour, ... Frontiers in Bioengineering and Biotechnology 8, 374, 2020 | 65 | 2020 |
Bioprinting of stem cell expansion lattices CD Lindsay, JG Roth, BL LeSavage, SC Heilshorn Acta biomaterialia 95, 225-235, 2019 | 49 | 2019 |
A robust method to generate mechanically anisotropic vascular smooth muscle cell sheets for vascular tissue engineering DE Backman, BL LeSavage, SB Shah, JY Wong Macromolecular bioscience 17 (6), 1600434, 2017 | 38 | 2017 |
Microrheology reveals simultaneous cell-mediated matrix stiffening and fluidization that underlie breast cancer invasion BA Krajina, BL LeSavage, JG Roth, AW Zhu, PC Cai, AJ Spakowitz, ... Science Advances 7 (8), eabe1969, 2021 | 37 | 2021 |
Production of elastin-like protein hydrogels for encapsulation and immunostaining of cells in 3D BL LeSavage, NA Suhar, CM Madl, SC Heilshorn Journal of Visualized Experiments: Jove, 57739, 2018 | 35 | 2018 |
Tunable hydrogel viscoelasticity modulates human neural maturation JG Roth, MS Huang, RS Navarro, JT Akram, BL LeSavage, SC Heilshorn Science Advances 9 (42), eadh8313, 2023 | 32 | 2023 |
Versatile and inexpensive Hall-Effect force sensor for mechanical characterization of soft biological materials DE Backman, BL LeSavage, JY Wong Journal of biomechanics 51, 118-122, 2017 | 19 | 2017 |
Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids BL LeSavage, D Zhang, C Huerta-López, AE Gilchrist, BA Krajina, ... Nature Materials 23 (8), 1138-1149, 2024 | 15 | 2024 |
Elastin‐like protein hydrogels with controllable stress relaxation rate and stiffness modulate endothelial cell function M Shayan, MS Huang, R Navarro, G Chiang, C Hu, BP Oropeza, ... Journal of Biomedical Materials Research Part A 111 (7), 896-909, 2023 | 13 | 2023 |
Neural progenitor cells alter chromatin organization and neurotrophin expression in response to 3D matrix degradability CM Madl, BL LeSavage, M Khariton, SC Heilshorn Advanced healthcare materials 9 (18), 2000754, 2020 | 10 | 2020 |
Tuning pro-survival effects of human induced pluripotent stem cell-derived exosomes using elastin-like polypeptides CH Lee, D Hunt, JG Roth, CC Chiu, RA Suhar, BL LeSavage, AJ Seymour, ... Biomaterials 291, 121864, 2022 | 3 | 2022 |
Defined matrices bring IBD to 3D BL LeSavage, SC Heilshorn Nature Materials 20 (2), 124-125, 2021 | 3 | 2021 |
Engineered Matrices Reveal Stiffness-Mediated Chemoresistance in Pancreatic Cancer Organoids D Zhang, BL LeSavage, C Huerta-López, A Gilchrist, SC Heilshorn 2024 AIChE Annual Meeting, 2024 | | 2024 |
Engineered Extracellular Matrices for Modeling Patient Tumors BL Lesavage Stanford University, 2022 | | 2022 |