Insights into drug discovery from natural products through structural modification J Chen, W Li, H Yao, J Xu Fitoterapia 103, 231-241, 2015 | 159 | 2015 |
Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures W Li, H Sun, S Xu, Z Zhu, J Xu Future medicinal chemistry 9 (15), 1765-1794, 2017 | 142 | 2017 |
Discovery of novel quinoline–chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity W Li, F Xu, W Shuai, H Sun, H Yao, C Ma, S Xu, H Yao, Z Zhu, DH Yang, ... Journal of medicinal chemistry 62 (2), 993-1013, 2018 | 123 | 2018 |
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site W Li, W Shuai, H Sun, F Xu, Y Bi, J Xu, C Ma, H Yao, Z Zhu, S Xu European Journal of Medicinal Chemistry 163, 428-442, 2019 | 75 | 2019 |
Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents F Xu, W Li, W Shuai, L Yang, Y Bi, C Ma, H Yao, S Xu, Z Zhu, J Xu European journal of medicinal chemistry 173, 1-14, 2019 | 60 | 2019 |
Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain W Li, Y Yin, W Shuai, F Xu, H Yao, J Liu, K Cheng, J Xu, Z Zhu, S Xu Bioorganic chemistry 83, 380-390, 2019 | 41 | 2019 |
Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities W Li, Y Yin, H Yao, W Shuai, H Sun, S Xu, J Liu, H Yao, Z Zhu, J Xu European Journal of Medicinal Chemistry 157, 1068-1080, 2018 | 37 | 2018 |
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine … W Li, H Sun, F Xu, W Shuai, J Liu, S Xu, H Yao, C Ma, Z Zhu, J Xu Bioorganic Chemistry 85, 49-59, 2019 | 36 | 2019 |
Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities H Zhu, W Li, W Shuai, Y Liu, L Yang, Y Tan, T Zheng, H Yao, J Xu, Z Zhu, ... European Journal of Medicinal Chemistry 216, 113316, 2021 | 23 | 2021 |
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors H Yao, F Xu, G Wang, S Xie, W Li, H Yao, C Ma, Z Zhu, J Xu, S Xu European Journal of Medicinal Chemistry 167, 485-498, 2019 | 23 | 2019 |
Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors W Shuai, X Li, W Li, F Xu, L Lu, H Yao, L Yang, H Zhu, S Xu, Z Zhu, J Xu European journal of medicinal chemistry 197, 112308, 2020 | 21 | 2020 |
Discovery of novel 4-arylisochromenes as anticancer agents inhibiting tubulin polymerization W Li, W Shuai, F Xu, H Sun, S Xu, H Yao, J Liu, H Yao, Z Zhu, J Xu ACS Medicinal Chemistry Letters 9 (10), 974-979, 2018 | 20 | 2018 |
Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease Y Liu, G Uras, I Onuwaje, W Li, H Yao, S Xu, X Li, X Li, J Phillips, S Allen, ... European Journal of Medicinal Chemistry 235, 114305, 2022 | 19 | 2022 |
Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors H Zhu, H Sun, Y Liu, Y Duan, J Liu, X Yang, W Li, S Qin, S Xu, Z Zhu, J Xu European Journal of Medicinal Chemistry 207, 112716, 2020 | 17 | 2020 |
Concise total synthesis of (±)-Deguelin and (±)-Tephrosin using a vinyl iodide as a key building block S Xu, G Wang, F Xu, W Li, A Lin, H Yao, J Xu Journal of natural products 81 (4), 1055-1059, 2018 | 13 | 2018 |
Design, synthesis and molecular modeling of isothiochromanone derivatives as acetylcholinesterase inhibitors W Shuai, W Li, Y Yin, L Yang, F Xu, S Xu, H Yao, Z Zhu, J Xu Future Medicinal Chemistry 11 (20), 2687-2699, 2019 | 5 | 2019 |
Corrigendum to" Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors"[Eur. J. Med. Chem. 197 (2020) 112308] W Shuai, X Li, W Li, F Xu, L Lu, H Yao, L Yang, H Zhu, S Xu, Z Zhu, J Xu European journal of medicinal chemistry 200, 112464, 2020 | | 2020 |