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Mackenzie Krone
Mackenzie Krone
Postdoctoral Fellow, Yale University
Verified email at yale.edu
Title
Cited by
Cited by
Year
More Than π–π–π Stacking: Contribution of Amide− π and CH− π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain
MW Krone, CR Travis, GY Lee, HJ Eckvahl, KN Houk, ML Waters
Journal of the American Chemical Society 142 (40), 17048-17056, 2020
422020
Investigation of trimethyllysine binding by the HP1 chromodomain via unnatural amino acid mutagenesis
SA Baril, AL Koenig, MW Krone, KI Albanese, CQ He, GY Lee, KN Houk, ...
Journal of the American Chemical Society 139 (48), 17253-17256, 2017
352017
Engineered reader proteins for enhanced detection of methylated lysine on histones
KI Albanese, MW Krone, CJ Petell, MM Parker, BD Strahl, EM Brustad, ...
ACS chemical biology 15 (1), 103-111, 2019
262019
Thermodynamic consequences of Tyr to Trp mutations in the cation–π-mediated binding of trimethyllysine by the HP1 chromodomain
MW Krone, KI Albanese, GO Leighton, CQ He, GY Lee, M Garcia-Borràs, ...
Chemical science 11 (13), 3495-3500, 2020
152020
High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression
G Veggiani, R Villaseñor, GD Martyn, JQ Tang, MW Krone, J Gu, C Chen, ...
Nature Communications 13 (1), 6975, 2022
112022
EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling
Z Hu, PH Chen, W Li, M Krone, S Zheng, J Saarbach, IU Velasco, J Hines, ...
Science Advances 10 (13), eadj7251, 2024
92024
Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC
JC Swartzel, MJ Bond, AP Pintado-Urbanc, M Daftary, MW Krone, ...
ACS chemical biology 17 (7), 1789-1798, 2022
52022
Nanomole Scale Screening of Fluorescent RNA‐Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors
JL Meidner, AF Frey, RA Zimmermann, MO Sabin, Z Nidoieva, AC Weldert, ...
Angewandte Chemie International Edition 63 (48), e202403792, 2024
32024
Development of Ligands and Degraders Targeting MAGE-A3
K Li, MW Krone, A Butrin, MJ Bond, BM Linhares, CM Crews
Journal of the American Chemical Society 146 (36), 24884-24891, 2024
12024
Screening fluoreszenter RNA‐Methyltransferase‐Sonden im Nanomolmaßstab ermöglicht die Entdeckung von METTL1‐Inhibitoren
JL Meidner, AF Frey, RA Zimmermann, MO Sabin, Z Nidoieva, AC Weldert, ...
Angewandte Chemie 136 (48), e202403792, 2024
2024
Next steps for targeted protein degradation
MW Krone, CM Crews
Cell Chemical Biology, 2024
2024
Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression
G Veggiani, R Villaseñor, GD Martyn, JQ Tang, MW Krone, J Gu, C Chen, ...
nature communications 13, 2022
2022
Characterizing and Engineering the Recognition of Histone Post-Translational Modifications by Reader Proteins
MW Krone
The University of North Carolina at Chapel Hill, 2020
2020
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