More Than π–π–π Stacking: Contribution of Amide− π and CH− π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain MW Krone, CR Travis, GY Lee, HJ Eckvahl, KN Houk, ML Waters Journal of the American Chemical Society 142 (40), 17048-17056, 2020 | 42 | 2020 |
Investigation of trimethyllysine binding by the HP1 chromodomain via unnatural amino acid mutagenesis SA Baril, AL Koenig, MW Krone, KI Albanese, CQ He, GY Lee, KN Houk, ... Journal of the American Chemical Society 139 (48), 17253-17256, 2017 | 35 | 2017 |
Engineered reader proteins for enhanced detection of methylated lysine on histones KI Albanese, MW Krone, CJ Petell, MM Parker, BD Strahl, EM Brustad, ... ACS chemical biology 15 (1), 103-111, 2019 | 26 | 2019 |
Thermodynamic consequences of Tyr to Trp mutations in the cation–π-mediated binding of trimethyllysine by the HP1 chromodomain MW Krone, KI Albanese, GO Leighton, CQ He, GY Lee, M Garcia-Borràs, ... Chemical science 11 (13), 3495-3500, 2020 | 15 | 2020 |
High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression G Veggiani, R Villaseñor, GD Martyn, JQ Tang, MW Krone, J Gu, C Chen, ... Nature Communications 13 (1), 6975, 2022 | 11 | 2022 |
EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling Z Hu, PH Chen, W Li, M Krone, S Zheng, J Saarbach, IU Velasco, J Hines, ... Science Advances 10 (13), eadj7251, 2024 | 9 | 2024 |
Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC JC Swartzel, MJ Bond, AP Pintado-Urbanc, M Daftary, MW Krone, ... ACS chemical biology 17 (7), 1789-1798, 2022 | 5 | 2022 |
Nanomole Scale Screening of Fluorescent RNA‐Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors JL Meidner, AF Frey, RA Zimmermann, MO Sabin, Z Nidoieva, AC Weldert, ... Angewandte Chemie International Edition 63 (48), e202403792, 2024 | 3 | 2024 |
Development of Ligands and Degraders Targeting MAGE-A3 K Li, MW Krone, A Butrin, MJ Bond, BM Linhares, CM Crews Journal of the American Chemical Society 146 (36), 24884-24891, 2024 | 1 | 2024 |
Screening fluoreszenter RNA‐Methyltransferase‐Sonden im Nanomolmaßstab ermöglicht die Entdeckung von METTL1‐Inhibitoren JL Meidner, AF Frey, RA Zimmermann, MO Sabin, Z Nidoieva, AC Weldert, ... Angewandte Chemie 136 (48), e202403792, 2024 | | 2024 |
Next steps for targeted protein degradation MW Krone, CM Crews Cell Chemical Biology, 2024 | | 2024 |
Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression G Veggiani, R Villaseñor, GD Martyn, JQ Tang, MW Krone, J Gu, C Chen, ... nature communications 13, 2022 | | 2022 |
Characterizing and Engineering the Recognition of Histone Post-Translational Modifications by Reader Proteins MW Krone The University of North Carolina at Chapel Hill, 2020 | | 2020 |