Emerging Technologies for Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain Barrier S Danica B, S Jagdeep K, C Willard J BioDrugs 32 (6), 547-559, 2018 | 91 | 2018 |
Brain penetration, target engagement, and disposition of the blood‐brain barrier‐crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1 CI Webster, N Caram‐Salas, AS Haqqani, G Thom, L Brown, K Rennie, ... The FASEB Journal 30 (5), 1927-1940, 2016 | 82 | 2016 |
DNA microarray analysis of striatal gene expression in symptomatic transgenic Huntington's mice (R6/2) reveals neuroinflammation and insulin associations SF Crocker, WJ Costain, HA Robertson Brain research 1088 (1), 176-186, 2006 | 63 | 2006 |
Design, synthesis, and dopamine receptor modulating activity of diketopiperazine peptidomimetics of L-prolyl-L-leucylglycinamide PW Baures, WH Ojala, WJ Costain, MC Ott, A Pradhan, WB Gleason, ... Journal of medicinal chemistry 40 (22), 3594-3600, 1997 | 60 | 1997 |
Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog V Verma, A Mann, W Costain, G Pontoriero, JM Castellano, K Skoblenick, ... Journal of Pharmacology and Experimental Therapeutics 315 (3), 1228-1236, 2005 | 52 | 2005 |
A new tool to assess ceramide bioactivity: 6-bromo-7-hydroxycoumarinyl-caged ceramide YA Kim, DMC Ramirez, WJ Costain, LJ Johnston, R Bittman Chemical Communications 47 (32), 9236-9238, 2011 | 41 | 2011 |
DNA microarray analysis of hippocampal gene expression measured twelve hours after hypoxia-ischemia in the mouse RW Gilbert, WJ Costain, ME Blanchard, KL Mullen, RW Currie, ... Journal of Cerebral Blood Flow & Metabolism 23 (10), 1195-1211, 2003 | 34 | 2003 |
Modulatory effects of PLG and its peptidomimetics on haloperidol-induced catalepsy in rats WJ Costain, AT Buckley, MC Evans, RK Mishra, RL Johnson Peptides 20 (6), 761-767, 1999 | 32 | 1999 |
Cerebral ischemia causes dysregulation of synaptic adhesion in mouse synaptosomes WJ Costain, I Rasquinha, JK Sandhu, P Rippstein, B Zurakowski, J Slinn, ... Journal of Cerebral Blood Flow & Metabolism 28 (1), 99-110, 2008 | 30 | 2008 |
Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons WJ Costain, JS Tauskela, I Rasquinha, T Comas, M Hewitt, V Marleau, ... European Journal of Pharmacology 786, 234-245, 2016 | 26 | 2016 |
Immediate‐early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice GA MacGibbon, LC Hamilton, SF Crocker, WJ Costain, KM Murphy, ... Journal of neuroscience research 67 (3), 372-378, 2002 | 25 | 2002 |
Modulation of agonist stimulated adenylyl cyclase and GTPase activity by l-pro-l-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes RK Mishra, MH Makman, WJ Costain, VD Nair, RL Johnson Neuroscience letters 269 (1), 21-24, 1999 | 25 | 1999 |
Proteomic analysis of synaptosomal protein expression reveals that cerebral ischemia alters lysosomal Psap processing WJ Costain, AS Haqqani, I Rasquinha, MS Giguere, J Slinn, B Zurakowski, ... Proteomics 10 (18), 3272-3291, 2010 | 24 | 2010 |
Role of skeletal muscle in mandible development I Rot, S Mardesic-Brakus, WJ Costain, M Saraga-Babic, B Kablar F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de …, 2014 | 22 | 2014 |
Cerebral ischemia induces neuronal expression of novel VL30 mouse retrotransposons bound to polyribosomes WJ Costain, I Rasquinha, T Graber, C Luebbert, E Preston, J Slinn, X Xie, ... Brain research 1094 (1), 24-37, 2006 | 18 | 2006 |
Biochemical characterization of a polysialyltransferase from Mannheimia haemolytica A2 and comparison to other bacterial polysialyltransferases T Lindhout, CR Bainbridge, WJ Costain, M Gilbert, WW Wakarchuk PLoS One 8 (7), e69888, 2013 | 17 | 2013 |
Alterations in inotropy, nitric oxide and cyclic GMP synthesis, protein phosphorylation and ADP-ribosylation in the endotoxin-treated rat myocardium and cardiomyocytes PV Sulakhe, L Sandirasegarane, JP Davis, XT Vo, WJ Costain, ... Molecular and cellular biochemistry 163, 305-318, 1996 | 17 | 1996 |
Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays JS Tauskela, T Comas, M Hewitt, A Aylsworth, X Zhao, M Martina, ... European Journal of Pharmacology 786, 148-160, 2016 | 16 | 2016 |
Electrophysiological-and neuropharmacological-based benchmarking of human induced pluripotent stem cell-derived and primary rodent neurons A Jezierski, E Baumann, A Aylsworth, WJ Costain, S Corluka, U Banderali, ... Stem Cell Reviews and Reports, 1-19, 2022 | 14 | 2022 |
Role of skeletal muscle in motor neuron development M Baguma-Nibasheka, A Fracassi, WJ Costain, S Moreno, B Kablar Universidad de Murcia. Departamento de Biología Celular e Histología, 2016 | 14 | 2016 |