The role of uptake and efflux transporters in the disposition of glucuronide and sulfate conjugates E Järvinen, F Deng, W Kiander, A Sinokki, H Kidron, N Sjöstedt Frontiers in Pharmacology 12, 802539, 2022 | 71 | 2022 |
Clinical and molecular perspectives on inflammation‐mediated regulation of drug metabolism and transport ACD Dunvald, E Järvinen, C Mortensen, TB Stage Clinical Pharmacology & Therapeutics 112 (2), 277-290, 2022 | 56 | 2022 |
Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP E Järvinen, F Deng, H Kidron, M Finel The Journal of Steroid Biochemistry and Molecular Biology 178, 99-107, 2018 | 33 | 2018 |
UGT1A10 is a high activity and important extrahepatic enzyme: why has its role in intestinal glucuronidation been frequently underestimated? J Troberg, E Jarvinen, GB Ge, L Yang, M Finel Molecular Pharmaceutics 14 (9), 2875-2883, 2017 | 27 | 2017 |
Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity J Troberg, E Järvinen, M Muniz, N Sneitz, J Mosorin, M Hagström, M Finel Drug Metabolism and Disposition 43 (1), 107-118, 2015 | 24 | 2015 |
Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7 RA Kallionpää, E Järvinen, M Finel The Journal of Steroid Biochemistry and Molecular Biology 154, 104-111, 2015 | 22 | 2015 |
3D spheroid primary human hepatocytes for prediction of cytochrome P450 and drug transporter induction E Järvinen, HS Hammer, O Pötz, M Ingelman‐Sundberg, TB Stage Clinical Pharmacology & Therapeutics 113 (6), 1284-1294, 2023 | 19 | 2023 |
Human efflux transport of testosterone, epitestosterone and other androgen glucuronides E Järvinen, H Kidron, M Finel The Journal of Steroid Biochemistry and Molecular Biology 197, 105518, 2020 | 18 | 2020 |
Tutorial: statistical analysis and reporting of clinical pharmacokinetic studies ACD Dunvald, DB Iversen, ALO Svendsen, K Agergaard, IB Kuhlmann, ... Clinical and Translational Science 15 (8), 1856-1866, 2022 | 11 | 2022 |
Selectivity in the efflux of glucuronides by human transporters: MRP4 is highly active toward 4-methylumbelliferone and 1-naphthol glucuronides, while MRP3 exhibits … E Jarvinen, J Troberg, H Kidron, M Finel Molecular Pharmaceutics 14 (10), 3299-3311, 2017 | 10 | 2017 |
Flucloxacillin is a weak inducer of CYP3A4 in healthy adults and 3D spheroid of primary human hepatocytes DB Iversen, ACD Dunvald, DM Jespersen, F Nielsen, K Brøsen, ... Clinical Pharmacology & Therapeutics 114 (2), 434-445, 2023 | 8 | 2023 |
Efflux transport of nicotine, cotinine and trans‐3′‐hydroxycotinine glucuronides by human hepatic transporters E Järvinen, N Sjöstedt, JB Koenderink, H Kidron, M Finel Basic & Clinical Pharmacology & Toxicology 125 (6), 490-498, 2019 | 6 | 2019 |
Dicloxacillin‐warfarin drug–drug interaction—A register‐based study and in vitro investigations in 3D spheroid primary human hepatocytes E Järvinen, AC Dalgård Dunvald, MT Ernst, HS Hammer, O Pötz, ... British Journal of Clinical Pharmacology 89 (8), 2614-2624, 2023 | 5 | 2023 |
A novel pathogenic UGT1A1 variant in a Sudanese child with type 1 Crigler-Najjar syndrome W Elfar, E Järvinen, W Ji, J Mosorin, AG Sega, AC Iuga, SJ Lobritto, ... Drug Metabolism and Disposition 47 (1), 45-48, 2019 | 5 | 2019 |
Evaluating Drug–Drug Interaction Risk Associated with Peptide Analogs Using advanced In Vitro Systems RA Nørgaard, DK Bhatt, E Järvinen, TB Stage, C Gabel-Jensen, A Galetin, ... Drug Metabolism and Disposition 52 (11), 1170-1180, 2024 | 3 | 2024 |
Thermodynamic solubility measurement without chemical analysis E Hokkala, CJ Strachan, M Agopov, E Järvinen, K Semjonov, J Heinämäki, ... International Journal of Pharmaceutics 653, 123890, 2024 | 2 | 2024 |
Dicloxacillin is an inducer of intestinal P‐glycoprotein but neither dicloxacillin nor flucloxacillin increases the risk of stroke/systemic embolism in direct oral … DB Iversen, ACD Dunvald, MT Ernst, S Abtahi, P Souverein, O Klungel, ... British Journal of Clinical Pharmacology 90 (12), 3252-3262, 2024 | | 2024 |
Intrinsic Hepatic Clearances of Selected Pharmaceuticals by Rainbow Trout S9 Fractions and Their Use in Estimating Bioconcentration Factors T Pihlaja, E Järvinen, TJ Oksanen, NE Vinkvist, T Sikanen SETAC Europe 34th Annual Meeting: Science-Based Solutions in Times of Crisis …, 2024 | | 2024 |
Prediction of intracellular tacrolimus concentrations in stabile kidney transplanted adults using a population pharmacokinetic modelling approach. K Katrine Agergaard, HC Thiesson, J Carstens, CE Staatz, E Järvinen, ... | | 2024 |
Population pharmacokinetic modelling of whole blood and intracellular tacrolimus in adult kidney transplanted patients. K Katrine Agergaard, HC Thiesson, J Carstens, CE Staatz, E Järvinen, ... | | 2024 |