| Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ... Nature 565 (7737), 43-48, 2019 | 585 | 2019 |
| STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease J Petrasek, A Iracheta-Vellve, T Csak, A Satishchandran, K Kodys, ... Proceedings of the National Academy of Sciences 110 (41), 16544-16549, 2013 | 428 | 2013 |
| Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ... Nature 595 (7866), 309-314, 2021 | 267 | 2021 |
| Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol‐induced liver damage, steatosis, and inflammation in mice A Ambade, P Lowe, K Kodys, D Catalano, B Gyongyosi, Y Cho, ... Hepatology 69 (3), 1105-1121, 2019 | 205 | 2019 |
| Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease J Petrasek, A Iracheta-Vellve, B Saha, A Satishchandran, K Kodys, ... Journal of Leucocyte Biology 98 (2), 249-256, 2015 | 183 | 2015 |
| Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via stimulator of interferon genes A Iracheta-Vellve, J Petrasek, B Gyongyosi, A Satishchandran, P Lowe, ... Journal of Biological Chemistry 291 (52), 26794-26805, 2016 | 152 | 2016 |
| MicroRNA 122, regulated by GRLH2, protects livers of mice and patients from ethanol-induced liver disease A Satishchandran, A Ambade, S Rao, YC Hsueh, A Iracheta-Vellve, ... Gastroenterology 154 (1), 238-252. e7, 2018 | 151 | 2018 |
| Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice A Iracheta-Vellve, J Petrasek, A Satishchandran, B Gyongyosi, B Saha, ... Journal of hepatology 63 (5), 1147-1155, 2015 | 149 | 2015 |
| Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure SJ Patel, JM Milwid, KR King, S Bohr, A Iracheta-Vellve, M Li, A Vitalo, ... Nature biotechnology 30 (2), 179-183, 2012 | 146 | 2012 |
| Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use TN Bukong, Y Cho, A Iracheta-Vellve, B Saha, P Lowe, A Adejumo, I Furi, ... Journal of Hepatology 69 (5), 1145-1154, 2018 | 141 | 2018 |
| Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90 B Saha, F Momen‐Heravi, I Furi, K Kodys, D Catalano, A Gangopadhyay, ... Hepatology 67 (5), 1986-2000, 2018 | 127 | 2018 |
| Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, Y Cho, ... Journal of neuroinflammation 15, 1-12, 2018 | 124 | 2018 |
| Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, A Ambade, ... PloS one 12 (3), e0174544, 2017 | 124 | 2017 |
| In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer J Dubrot, PP Du, SK Lane-Reticker, EA Kessler, AJ Muscato, A Mehta, ... Nature Immunology 23 (10), 1495-1506, 2022 | 123 | 2022 |
| Macrophage‐specific hypoxia‐inducible factor‐1α contributes to impaired autophagic flux in nonalcoholic steatohepatitis X Wang, M de Carvalho Ribeiro, A Iracheta‐Vellve, P Lowe, A Ambade, ... Hepatology 69 (2), 545-563, 2019 | 123 | 2019 |
| MicroRNA-155 deficiency attenuates liver steatosis and fibrosis without reducing inflammation in a mouse model of steatohepatitis T Csak, S Bala, D Lippai, K Kodys, D Catalano, A Iracheta-Vellve, ... PLoS One 10 (6), e0129251, 2015 | 102 | 2015 |
| FXR and TGR5 agonists ameliorate liver injury, steatosis, and inflammation after binge or prolonged alcohol feeding in mice A Iracheta‐Vellve, CD Calenda, J Petrasek, A Ambade, K Kodys, ... Hepatology communications 2 (11), 1379-1391, 2018 | 96 | 2018 |
| Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease S Bala, T Csak, K Kodys, D Catalano, A Ambade, I Furi, P Lowe, Y Cho, ... Journal of Leukocyte Biology 102 (2), 487-498, 2017 | 95 | 2017 |
| Targeting TBK1 to overcome resistance to cancer immunotherapy Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ... Nature 615 (7950), 158-167, 2023 | 87 | 2023 |
| Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease TN Bukong, A Iracheta‐Vellve, B Saha, A Ambade, A Satishchandran, ... Hepatology 64 (4), 1057-1071, 2016 | 79 | 2016 |
Aditya Ambade, PhDCharles River Labs, Shrewsbury, MA, United StatesVerified email at crl.com