Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature Methods, 1-14, 2020 | 725 | 2020 |
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease A Douangamath, D Fearon, P Gehrtz, T Krojer, P Lukacik, CD Owen, ... Nature communications 11 (1), 1-11, 2020 | 509 | 2020 |
Sub‐angstrom modeling of complexes between flexible peptides and globular proteins B Raveh, N London, O Schueler‐Furman Proteins: Structure, Function, and Bioinformatics 78 (9), 2029-2040, 2010 | 457 | 2010 |
The structural basis of peptide-protein binding strategies N London, D Movshovitz-Attias, O Schueler-Furman Structure 18 (2), 188-199, 2010 | 450 | 2010 |
Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions N London, B Raveh, E Cohen, G Fathi, O Schueler-Furman Nucleic Acids Research 39 (suppl 2), W249-W253, 2011 | 437 | 2011 |
Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors B Raveh, N London, L Zimmerman, O Schueler-Furman PloS one 6 (4), e18934, 2011 | 322 | 2011 |
Rapid covalent-probe discovery by electrophile-fragment screening E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ... Journal of the American Chemical Society, 2019 | 290 | 2019 |
Covalent docking of large libraries for the discovery of chemical probes N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ... Nature Chemical Biology 10 (12), 1066-1072, 2014 | 273 | 2014 |
Druggable protein–protein interactions–from hot spots to hot segments N London, B Raveh, O Schueler-Furman Current opinion in chemical biology 17 (6), 952-959, 2013 | 260 | 2013 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 209 | 2022 |
Relacin, a novel antibacterial agent targeting the Stringent Response E Wexselblatt, Y Oppenheimer-Shaanan, I Kaspy, N London, ... PLoS pathogens 8 (9), e1002925, 2012 | 195 | 2012 |
HSP40 proteins use class-specific regulation to drive HSP70 functional diversity O Faust, M Abayev-Avraham, AS Wentink, M Maurer, NB Nillegoda, ... Nature, 1-6, 2020 | 184 | 2020 |
Ubiquitination and Degradation of the Inhibitors of NF-κB N Kanarek, N London, O Schueler-Furman, Y Ben-Neriah Cold Spring Harbor perspectives in biology 2 (2), a000166, 2010 | 181 | 2010 |
Can self‐inhibitory peptides be derived from the interfaces of globular protein–protein interactions? N London, B Raveh, D Movshovitz‐Attias, O Schueler‐Furman Proteins: Structure, Function, and Bioinformatics 78 (15), 3140-3149, 2010 | 180 | 2010 |
Efficient targeted degradation via reversible and irreversible covalent PROTACs R Gabizon, A Shraga, P Gehrtz, E Livnah, Y Shorer, N Gurwicz, L Avram, ... Journal of the American Chemical Society, 2020 | 179 | 2020 |
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy K Koikawa, S Kibe, F Suizu, N Sekino, N Kim, TD Manz, BJ Pinch, ... Cell, 2021 | 160 | 2021 |
Community-wide assessment of protein-interface modeling suggests improvements to design methodology SJ Fleishman, TA Whitehead, EM Strauch, JE Corn, S Qin, HX Zhou, ... Journal of molecular biology 414 (2), 289-302, 2011 | 159 | 2011 |
PRosettaC: Rosetta based modeling of PROTAC mediated ternary complexes D Zaidman, J Prilusky, N London Journal of Chemical Information and Modeling, 2020 | 147 | 2020 |
Peptide docking and structure-based characterization of peptide binding: from knowledge to know-how N London, B Raveh, O Schueler-Furman Current opinion in structural biology 23 (6), 894-902, 2013 | 120 | 2013 |
The Escherichia coli extracellular death factor EDF induces the endoribonucleolytic activities of the toxins MazF and ChpBK M Belitsky, H Avshalom, A Erental, I Yelin, S Kumar, N London, M Sperber, ... Molecular cell 41 (6), 625-635, 2011 | 120 | 2011 |