| The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans N King, MJ Westbrook, SL Young, A Kuo, M Abedin, J Chapman, ... Nature 451 (7180), 783-788, 2008 | 1259 | 2008 |
| Endoplasmic reticulum stress sensing in the unfolded protein response BM Gardner, D Pincus, K Gotthardt, CM Gallagher, P Walter Cold Spring Harbor perspectives in biology 5 (3), a013169, 2013 | 846 | 2013 |
| BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response D Pincus, MW Chevalier, T Aragón, E van Anken, SE Vidal, H El-Samad, ... PLoS biology 8 (7), e1000415, 2010 | 518 | 2010 |
| Messenger RNA targeting to endoplasmic reticulum stress signalling sites T Aragón, E Van Anken, D Pincus, IM Serafimova, AV Korennykh, ... Nature 457 (7230), 736-740, 2009 | 447 | 2009 |
| In silico feedback for in vivo regulation of a gene expression circuit A Milias-Argeitis, S Summers, J Stewart-Ornstein, I Zuleta, D Pincus, ... Nature biotechnology 29 (12), 1114-1116, 2011 | 338 | 2011 |
| Negative feedback that improves information transmission in yeast signalling RC Yu, CG Pesce, A Colman-Lerner, L Lok, D Pincus, E Serra, M Holl, ... Nature 456 (7223), 755-761, 2008 | 267 | 2008 |
| Lipidomic analysis of α-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment S Fanning, A Haque, T Imberdis, V Baru, MI Barrasa, S Nuber, D Termine, ... Molecular cell 73 (5), 1001-1014. e8, 2019 | 262 | 2019 |
| Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation X Zheng, J Krakowiak, N Patel, A Beyzavi, J Ezike, AS Khalil, D Pincus elife 5, e18638, 2016 | 255 | 2016 |
| Defining the essential function of yeast Hsf1 reveals a compact transcriptional program for maintaining eukaryotic proteostasis EJ Solís, JP Pandey, X Zheng, DX Jin, PB Gupta, EM Airoldi, D Pincus, ... Molecular cell 63 (1), 60-71, 2016 | 212 | 2016 |
| Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity C Rubio, D Pincus, A Korennykh, S Schuck, H El-Samad, P Walter Journal of Cell Biology 193 (1), 171-184, 2011 | 186 | 2011 |
| Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages D Pincus, I Letunic, P Bork, WA Lim Proceedings of the National Academy of Sciences 105 (28), 9680-9684, 2008 | 165 | 2008 |
| Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response J Krakowiak, X Zheng, N Patel, ZA Feder, J Anandhakumar, K Valerius, ... Elife 7, e31668, 2018 | 152 | 2018 |
| Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness BW Tye, N Commins, LV Ryazanova, M Wühr, M Springer, D Pincus, ... elife 8, e43002, 2019 | 118 | 2019 |
| Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range TM Thomson, KR Benjamin, A Bush, T Love, D Pincus, O Resnekov, ... Proceedings of the National Academy of Sciences 108 (50), 20265-20270, 2011 | 92 | 2011 |
| tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae JR Damon, D Pincus, HL Ploegh Molecular biology of the cell 26 (2), 270-282, 2015 | 85 | 2015 |
| Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses PM Fordyce, D Pincus, P Kimmig, CS Nelson, H El-Samad, P Walter, ... Proceedings of the National Academy of Sciences 109 (45), E3084-E3093, 2012 | 78 | 2012 |
| Regulation of Hsf1 and the heat shock response D Pincus HSF1 and molecular chaperones in biology and cancer, 41-50, 2020 | 76 | 2020 |
| m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis GG Bushkin, D Pincus, JT Morgan, K Richardson, C Lewis, SH Chan, ... Nature communications 10 (1), 3414, 2019 | 69 | 2019 |
| Translocon declogger Ste24 protects against IAPP oligomer-induced proteotoxicity C Kayatekin, A Amasino, G Gaglia, J Flannick, JM Bonner, S Fanning, ... Cell 173 (1), 62-73. e9, 2018 | 64 | 2018 |
| Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1 E van Anken, D Pincus, S Coyle, T Aragón, C Osman, F Lari, ... Elife 3, e05031, 2014 | 64 | 2014 |
