Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage JM Gutiérrez, A Rucavado, T Escalante, C Díaz Toxicon 45 (8), 997-1011, 2005 | 519 | 2005 |
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases T Escalante, A Rucavado, JW Fox, JM Gutiérrez Journal of proteomics 74 (9), 1781-1794, 2011 | 297 | 2011 |
Experimental pathology of local tissue damage induced by Bothrops asper snake venom JM Gutiérrez, A Rucavado, F Chaves, C Díaz, T Escalante Toxicon 54 (7), 958-975, 2009 | 226 | 2009 |
Hemorrhage caused by snake venom metalloproteinases: a journey of discovery and understanding JM Gutiérrez, T Escalante, A Rucavado, C Herrera Toxins 8 (4), 93, 2016 | 219 | 2016 |
Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom JM Gutiérrez, T Escalante, A Rucavado Toxicon 54 (7), 976-987, 2009 | 182 | 2009 |
Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase … A Rucavado, T Escalante, A Franceschi, F Chaves, G León, Y Cury, ... The American journal of tropical medicine and hygiene 63 (5), 313-319, 2000 | 158 | 2000 |
Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue‐damaging toxins from the venom of the snake Bothrops asper A Rucavado, T Escalante, CFP Teixeira, CM Fernándes, C Díaz, ... Mediators of Inflammation 11 (2), 121-128, 2002 | 144 | 2002 |
Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the … T Escalante, A Franceschi, A Rucavado, JM Gutiérrez Biochemical pharmacology 60 (2), 269-274, 2000 | 131 | 2000 |
Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: a biochemical and immunohistochemical study T Escalante, J Shannon, AM Moura-da-Silva, JM Gutiérrez, JW Fox Archives of biochemistry and biophysics 455 (2), 144-153, 2006 | 130 | 2006 |
Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage C Herrera, T Escalante, MB Voisin, A Rucavado, D Morazán, JKA Macêdo, ... PLoS neglected tropical diseases 9 (4), e0003731, 2015 | 118 | 2015 |
A comprehensive view of the structural and functional alterations of extracellular matrix by snake venom metalloproteinases (SVMPs): Novel perspectives on the pathophysiology … JM Gutiérrez, T Escalante, A Rucavado, C Herrera, JW Fox Toxins 8 (10), 304, 2016 | 117 | 2016 |
Snake venom metalloproteinases. Biological roles and participation in the pathophysiology of envenomation JM Gutiérrez, A Rucavado, T Escalante Handbook of venoms and toxins of reptiles 115, 138, 2010 | 107 | 2010 |
Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases T Escalante, N Ortiz, A Rucavado, EF Sanchez, M Richardson, JW Fox, ... PloS one 6 (12), e28017, 2011 | 100 | 2011 |
Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom A Rucavado, M Soto, T Escalante, GD Loría, R Arni, JM Gutiérrez Thrombosis and haemostasis 94 (07), 123-131, 2005 | 100 | 2005 |
Skin pathology induced by snake venom metalloproteinase: acute damage, revascularization, and re-epithelization in a mouse ear model N Jiménez, T Escalante, JM Gutiérrez, A Rucavado Journal of investigative dermatology 128 (10), 2421-2428, 2008 | 98 | 2008 |
Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation A Rucavado, T Escalante, JM Gutiérrez Toxicon 43 (4), 417-424, 2004 | 96 | 2004 |
Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins T Escalante, A Rucavado, AFM Pinto, RMS Terra, JM Gutiérrez, JW Fox Journal of proteome research 8 (11), 5120-5131, 2009 | 86 | 2009 |
Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom T Escalante, J Núñez, AMM da Silva, A Rucavado, RDG Theakston, ... Toxicology and applied pharmacology 193 (1), 17-28, 2003 | 85 | 2003 |
Characterization of aspercetin, a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase … A Rucavado, M Soto, AS Kamiguti, DG Theakston, JW Fox, T Escalante, ... Thrombosis and haemostasis 85 (04), 710-715, 2001 | 75 | 2001 |
Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin P Gallagher, Y Bao, SMT Serrano, GD Laing, RDG Theakston, ... Archives of biochemistry and biophysics 441 (1), 1-15, 2005 | 70 | 2005 |