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Alexander Ferrena
Alexander Ferrena
PhD Candidate, Albert Einstein College of Medicine
Verified email at einsteinmed.edu - Homepage
Title
Cited by
Cited by
Year
Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development
C De Bono, Y Liu, A Ferrena, A Valentine, D Zheng, BE Morrow
Nature communications 14 (1), 1551, 2023
222023
The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma
J Wang, O Aldahamsheh, A Ferrena, H Borjihan, A Singla, S Yaguare, ...
Annals of the New York Academy of Sciences 1490 (1), 90-104, 2021
172021
Systematic comparison of pancreatic ductal adenocarcinoma models identifies a conserved highly plastic basal cell state
KL Pitter, O Grbovic-Huezo, S Joost, A Singhal, M Blum, K Wu, M Holm, ...
Cancer research 82 (19), 3549-3560, 2022
152022
SKP2 Knockout in Rb1/p53–Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis
A Ferrena, J Wang, R Zhang, B Karadal-Ferrena, W Al-Hardan, S Singh, ...
Molecular cancer therapeutics 23 (2), 223-234, 2024
72024
Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma
J Wang, A Ferrena, R Zhang, S Singh, V Viscarret, W Al-Harden, ...
Oncogene 43 (13), 962-975, 2024
52024
Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis
X Zhuang, Q Wang, S Joost, A Ferrena, DT Humphreys, Z Li, M Blum, ...
Nature 637 (8044), 184-194, 2025
32025
Targeting SKP2 by p27 Inhibits stemness and prolong the survival in osteosarcoma
J Wang, O Aldahamsheh, A Ferrena, S Singh, A Singla, H Borjihan, ...
Cancer Research 81 (13_Supplement), 2008-2008, 2021
22021
Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis
X Zhuang, Q Wang, S Joost, A Ferrena, DT Humphreys, Z Li, M Blum, ...
BioRxiv, 2024.06. 23.600305, 2024
12024
scDAPP: a comprehensive single-cell transcriptomics analysis pipeline optimized for cross-group comparison
A Ferrena, XY Zheng, K Jackson, B Hoang, BE Morrow, D Zheng
NAR Genomics and Bioinformatics 6 (4), lqae134, 2024
2024
Abstract A015: Aging limits stemness and tumor development in the lung by reprogramming iron homeostasis
X Zhuang, Q Wang, S Joost, A Ferrena, M Blum, K Krause, Z Li, D Zheng, ...
Cancer Research 84 (22_Supplement), A015-A015, 2024
2024
Six3 and Six6 jointly control diverse target genes in multiple cell populations over developmental trajectories of mouse embryonic retinal progenitor cells
A Ferrena, X Zhang, R Shrestha, D Zheng, W Liu
Plos one 19 (10), e0308839, 2024
2024
The evolution of the multidisciplinary tumor board in orthopedic oncology: from its historical roots to its future potential
B Goker, M Shea, R Zhang, J Wang, A Ferrena, SS Chae, H Borjihan, ...
Holistic Integrative Oncology 3 (1), 36, 2024
2024
Novel candidate metastasis‐associated genes for synovial sarcoma
Z Zhao, J Niu, J Wang, R Zhang, H Liang, Y Ma, A Ferrena, W Wang, ...
Journal of Cellular and Molecular Medicine 28 (14), e18541, 2024
2024
Six3 and Six6 jointly control diverse target genes to regulate cell states over developmental trajectories of mouse embryonic retinal progenitor cells
W Liu, A Ferrena, X Zhang, R Shrestha, D Zheng
Investigative Ophthalmology & Visual Science 65 (7), 6688-6688, 2024
2024
Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional …
A Ferrena, R Zhang, J Wang, XY Zheng, B Göker, H Borjihan, SS Chae, ...
bioRxiv, 2024
2024
Molecular and Clinical Implications of SKP2 Inhibition in Osteosarcoma
A Ferrena
Albert Einstein College of Medicine, 2024
2024
Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values
R Misra, A Ferrena, D Zheng
bioRxiv, 2024.02. 22.581665, 2024
2024
Six3 and Six6 jointly regulate the identities and developmental trajectories of multipotent retinal progenitor cells in the mouse retina
A Ferrena, X Zhang, R Shrestha, D Zheng, W Liu
bioRxiv, 2023.05. 03.539288, 2023
2023
SKP2 knockout induces macrophage infiltration in p53/Rb1 null transgenic mouse models of osteosarcoma and drives gene expression correlated with improved survival in patients
A Ferrena, J Wang, R Zhang, R Yang, D Geller, B Hoang, D Zheng
Cancer Research 83 (7_Supplement), 553-553, 2023
2023
Targeted inhibition of the E3 ligase SCFSkp2/Cks1 has survival benefit and antitumor activity in osteosarcoma
J Wang, A Ferrena, R Zhang, S Singh, H Zhao, D Zheng, H Borjihan, ...
Cancer Research 82 (12_Supplement), 6188-6188, 2022
2022
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