| Potency of progestogens used in hormonal therapy: toward understanding differential actions JP Hapgood, D Africander, R Louw, RM Ray, JM Rohwer The Journal of steroid biochemistry and molecular biology 142, 39-47, 2014 | 114 | 2014 |
| Comparing the androgenic and estrogenic properties of progestins used in contraception and hormone therapy R Louw-du Toit, MS Perkins, JP Hapgood, D Africander Biochemical and biophysical research communications 491 (1), 140-146, 2017 | 92 | 2017 |
| Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract D Africander, R Louw, N Verhoog, D Noeth, JP Hapgood Contraception 84 (4), 423-435, 2011 | 76 | 2011 |
| Medroxyprogesterone acetate differentially regulates interleukin (IL)-12 and IL-10 in a human ectocervical epithelial cell line in a glucocorticoid receptor (GR)-dependent manner R Louw-du Toit, JP Hapgood, D Africander Journal of Biological Chemistry 289 (45), 31136-31149, 2014 | 44 | 2014 |
| A comparative characterization of estrogens used in hormone therapy via estrogen receptor (ER)-α and-β MS Perkins, R Louw-du Toit, D Africander The Journal of Steroid Biochemistry and Molecular Biology 174, 27-39, 2017 | 42 | 2017 |
| Investigating the anti-mineralocorticoid properties of synthetic progestins used in hormone therapy D Africander, R Louw, JP Hapgood Biochemical and biophysical research communications 433 (3), 305-310, 2013 | 40 | 2013 |
| Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception AJ Bick, R Louw-du Toit, SB Skosana, D Africander, JP Hapgood Pharmacology & therapeutics 222, 107789, 2021 | 39 | 2021 |
| Hormone therapy and breast cancer: emerging steroid receptor mechanisms MS Perkins, R Louw-du Toit, D Africander Journal of Molecular Endocrinology 61 (4), R133-R160, 2018 | 32 | 2018 |
| 16α-hydroxyprogesterone: origin, biosynthesis and receptor interaction KH Storbeck, P Swart, D Africander, R Conradie, R Louw, AC Swart Molecular and cellular endocrinology 336 (1-2), 92-101, 2011 | 31 | 2011 |
| 11-Oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool L Barnard, L Schiffer, R Louw Du-Toit, JA Tamblyn, S Chen, D Africander, ... Endocrinology 162 (3), bqaa231, 2021 | 26 | 2021 |
| Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones R Louw-du Toit, KH Storbeck, M Cartwright, A Cabral, D Africander Molecular and cellular endocrinology 441, 31-45, 2017 | 20 | 2017 |
| Differential metabolism of clinically-relevant progestogens in cell lines and tissue: Implications for biological mechanisms SB Skosana, JG Woodland, M Cartwright, K Enfield, M Komane, ... The Journal of steroid biochemistry and molecular biology 189, 145-153, 2019 | 17 | 2019 |
| Differential off-target glucocorticoid activity of progestins used in endocrine therapy M Komane, C Avenant, R Louw-du Toit, DJ Africander, JP Hapgood Steroids 182, 108998, 2022 | 15 | 2022 |
| A direct comparison of the transcriptional activities of progestins used in contraception and menopausal hormone therapy via the mineralocorticoid receptor R Louw-du Toit, JP Hapgood, D Africander Biochemical and biophysical research communications 526 (2), 466-471, 2020 | 15 | 2020 |
| Characterisation of progestins used in hormonal contraception and progesterone via the progesterone receptor K Enfield, M Cartwright, R Louw-du Toit, C Avenant, D Africander, ... Biochemical and biophysical research communications 533 (4), 879-885, 2020 | 13 | 2020 |
| Fourth-generation progestins inhibit 3β-hydroxysteroid dehydrogenase type 2 and modulate the biosynthesis of endogenous steroids R Louw-du Toit, MS Perkins, JL Snoep, KH Storbeck, D Africander PloS one 11 (10), e0164170, 2016 | 13 | 2016 |
| Progestins in menopausal hormone therapy and breast cancer risk: The debate continues D Africander, R Louw-du Toit Current Opinion in Endocrine and Metabolic Research 15, 24-30, 2020 | 9 | 2020 |
| The metabolic fate and receptor interaction of 16α-hydroxyprogesterone and its 5α-reduced metabolite, 16α-hydroxy-dihydroprogesterone D van Rooyen, T du Toit, R Louw-du Toit, D Africander, P Swart, AC Swart Molecular and cellular endocrinology 441, 86-98, 2017 | 7 | 2017 |
| Upregulation of an estrogen receptor-regulated gene by first generation progestins requires both the progesterone receptor and estrogen receptor alpha MS Perkins, R Louw-du Toit, H Jackson, M Simons, D Africander Frontiers in Endocrinology 13, 959396, 2022 | 5 | 2022 |
| Progesterone receptor isoform ratios influence the transcriptional activity of progestins via the progesterone receptor M Cartwright, R Louw-du Toit, H Jackson, MJ van Vuuren, D Africander The Journal of Steroid Biochemistry and Molecular Biology 232, 106348, 2023 | 4 | 2023 |
