Dynamic remodeling of membrane composition drives cell cycle through primary cilia excision SC Phua, S Chiba, M Suzuki, E Su, EC Roberson, GV Pusapati, M Setou, ... Cell 168 (1), 264-279. e15, 2017 | 334 | 2017 |
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity Y Carmi, MH Spitzer, IL Linde, BM Burt, TR Prestwood, N Perlman, ... Nature 521 (7550), 99-104, 2015 | 258 | 2015 |
CRISPR screens uncover genes that regulate target cell sensitivity to the morphogen sonic hedgehog GV Pusapati, JH Kong, BB Patel, A Krishnan, A Sagner, M Kinnebrew, ... Developmental cell 44 (1), 113-129. e8, 2018 | 149 | 2018 |
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells A Kleger, T Seufferlein, D Malan, M Tischendorf, A Storch, A Wolheim, ... Circulation 122 (18), 1823-1836, 2010 | 143 | 2010 |
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling M Kinnebrew, EJ Iverson, BB Patel, GV Pusapati, JH Kong, KA Johnson, ... Elife 8, e50051, 2019 | 127 | 2019 |
EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia GV Pusapati, CE Hughes, KV Dorn, D Zhang, P Sugianto, L Aravind, ... Developmental cell 28 (5), 483-496, 2014 | 100 | 2014 |
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours N Azoitei, GV Pusapati, A Kleger, P Möller, R Küfer, F Genze, M Wagner, ... Gut 59 (10), 1316-1330, 2010 | 89 | 2010 |
Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase GV Pusapati, G Luchetti, SR Pfeffer Journal of Biological Chemistry 287 (50), 42129-42137, 2012 | 76 | 2012 |
Role of the Second Cysteine-rich Domain and Pro275 in Protein Kinase D2 Interaction with ADP-Ribosylation Factor 1, Trans-Golgi Network Recruitment, and … GV Pusapati, D Krndija, M Armacki, G von Wichert, J von Blume, ... Molecular biology of the cell 21 (6), 1011-1022, 2010 | 69 | 2010 |
Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling SR Hong, CL Wang, YS Huang, YC Chang, YC Chang, GV Pusapati, ... Nature communications 9 (1), 1732, 2018 | 68 | 2018 |
G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog GV Pusapati, JH Kong, BB Patel, M Gouti, A Sagner, R Sircar, G Luchetti, ... Science Signaling 11 (516), eaao5749, 2018 | 65 | 2018 |
R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling R Dubey, P van Kerkhof, I Jordens, T Malinauskas, GV Pusapati, ... Elife 9, e54469, 2020 | 51 | 2020 |
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation N Azoitei, A Kleger, N Schoo, DR Thal, C Brunner, GV Pusapati, ... Neuro-oncology 13 (7), 710-724, 2011 | 51 | 2011 |
An essential role for Grk2 in Hedgehog signalling downstream of Smoothened Z Zhao, RTH Lee, GV Pusapati, A Iyu, R Rohatgi, PW Ingham EMBO reports 17 (5), 739-752, 2016 | 49 | 2016 |
RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36 RM Nottingham, GV Pusapati, IG Ganley, FA Barr, DG Lambright, ... Journal of Biological Chemistry 287 (27), 22740-22748, 2012 | 32 | 2012 |
A membrane-tethered ubiquitination pathway regulates Hedgehog signaling and heart development JH Kong, CB Young, GV Pusapati, CB Patel, S Ho, A Krishnan, JHI Lin, ... Developmental cell 55 (4), 432-449. e12, 2020 | 30 | 2020 |
Protein kinase D2 is an essential regulator of murine myoblast differentiation A Kleger, C Loebnitz, GV Pusapati, M Armacki, M Müller, S Tümpel, ... PloS one 6 (1), e14599, 2011 | 29 | 2011 |
A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis M Armacki, G Joodi, SC Nimmagadda, L De Kimpe, GV Pusapati, ... Oncogene 33 (9), 1167-1180, 2014 | 28 | 2014 |
Protein kinase D regulates RhoA activity via rhotekin phosphorylation GV Pusapati, T Eiseler, A Rykx, S Vandoninck, R Derua, E Waelkens, ... Journal of Biological Chemistry 287 (12), 9473-9483, 2012 | 25 | 2012 |
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling M Bosakova, SP Abraham, A Nita, E Hruba, M Buchtova, SP Taylor, ... EMBO Molecular Medicine 12 (11), e11739, 2020 | 22 | 2020 |