m6A regulator-based methylation modification patterns characterized by distinct tumor microenvironment immune profiles in colon cancer W Chong, L Shang, J Liu, Z Fang, F Du, H Wu, Y Liu, Z Wang, Y Chen, ... Theranostics 11 (5), 2201, 2021 | 180 | 2021 |
Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2 L Chen, JE Manautou, TP Rasmussen, X Zhong Acta Pharmaceutica Sinica B 9 (4), 659-674, 2019 | 77 | 2019 |
A transcriptional regulatory network containing nuclear receptors and long noncoding RNAs controls basal and drug-induced expression of cytochrome P450s in HepaRG cells L Chen, Y Bao, SC Piekos, K Zhu, L Zhang, X Zhong Molecular Pharmacology 94 (1), 749-759, 2018 | 52 | 2018 |
Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids G Pettinato, MF Coughlan, X Zhang, L Chen, U Khan, M Glyavina, ... Science Advances 7 (34), eabj2800, 2021 | 32 | 2021 |
The HNF1α-regulated lncRNA HNF1α-AS1 is involved in the regulation of cytochrome P450 expression in human liver tissues and Huh7 cells Y Wang, L Yan, J Liu, S Chen, G Liu, Y Nie, P Wang, W Yang, L Chen, ... Journal of Pharmacology and Experimental Therapeutics 368 (3), 353-362, 2019 | 32 | 2019 |
Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice P Wang, X Shao, Y Bao, J Zhu, L Chen, L Zhang, X Ma, X Zhong Acta Pharmaceutica Sinica B 10 (1), 171-185, 2020 | 21 | 2020 |
The roles of long noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in drug metabolism and human diseases L Chen, Y Bao, S Jiang, X Zhong Non-coding RNA 6 (2), 24, 2020 | 19 | 2020 |
Knockdown of long noncoding RNAs hepatocyte nuclear factor 1α antisense RNA 1 and hepatocyte nuclear factor 4α antisense RNA 1 alters susceptibility of acetaminophen-induced … L Chen, P Wang, JE Manautou, X Zhong Molecular Pharmacology 97 (4), 278-286, 2020 | 19 | 2020 |
The role of H19, a long non-coding RNA, in mouse liver postnatal maturation C Pope, SC Piekos, L Chen, S Mishra, X Zhong PLoS One 12 (11), e0187557, 2017 | 16 | 2017 |
In vivo detection of bile duct pre-cancer with endoscopic light scattering spectroscopy DK Pleskow, MS Sawhney, PK Upputuri, TM Berzin, MF Coughlan, ... Nature Communications 14 (1), 109, 2023 | 15 | 2023 |
Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver L Chen, P Wang, R Bahal, JE Manautou, X Zhong PLoS One 14 (12), e0227102, 2019 | 15 | 2019 |
Epalrestat stimulated oxidative stress, inflammation, and fibrogenesis in mouse liver Y Le, L Chen, Y Zhang, P Bu, G Dai, X Cheng Toxicological Sciences 163 (2), 397-408, 2018 | 13 | 2018 |
Consequences of phenytoin exposure on hepatic cytochrome P450 expression during postnatal liver maturation in mice SC Piekos, L Chen, P Wang, J Shi, S Yaqoob, HJ Zhu, X Ma, X Zhong Drug Metabolism and Disposition 46 (8), 1241-1250, 2018 | 9 | 2018 |
Coherent confocal light scattering spectroscopic microscopy evaluates cancer progression and aggressiveness in live cells and tissue DK Pleskow, L Zhang, V Turzhitsky, MF Coughlan, U Khan, X Zhang, ... ACS photonics 8 (7), 2050-2059, 2021 | 7 | 2021 |
Effects of overexpression of fibroblast growth factor 15/19 on hepatic drug metabolizing enzymes D Rizzolo, B Kong, S Piekos, L Chen, X Zhong, J Lu, J Shi, H Zhu, Q Yang, ... Drug Metabolism and Disposition 50 (4), 468-477, 2022 | 4 | 2022 |
Biopsy channel of the endoscope as a potential source of infectious droplets during GI endoscopy MF Coughlan, MS Sawhney, DK Pleskow, U Khan, A Silva-Santisteban, ... Gastrointestinal endoscopy 96 (5), 764-770, 2022 | 3 | 2022 |
Impact on acetaminophen‐induced hepatotoxicity by long non‐coding RNAs HNF1α‐AS1 and HNF4α‐AS1 in HepaRG cells L Chen, JE Manautou, X Zhong The FASEB Journal 33 (S1), 506.6-506.6, 2019 | 3 | 2019 |
Phenobarbital Increased Hepatic Toxicity of Acetaminophen due to Cytochrome P450 Induction in Young and Adult Mice X Shao, P Wang, Y Bao, L Chen, X Zhong The FASEB Journal 33 (S1), 506.7-506.7, 2019 | 1 | 2019 |
C-CLASS microscopy allows the detection of nanoscale changes in chromatin structure MF Coughlan, G Pettinato, M Glyavina, X Zhang, L Chen, U Khan, ... European Conference on Biomedical Optics, 126300U, 2023 | | 2023 |
246.8: In Vivo Monitoring of Liver Organoids Differentiation Using Live-Screening-Optical Technologies G Pettinato, MF Coughlan, X Zhang, L Chen, M Glyavina, YN Zakharov, ... Transplantation 106 (9S), S165-S166, 2022 | | 2022 |