| Autotaxin in the crosshairs: taking aim at cancer and other inflammatory conditions MGK Benesch, YM Ko, TPW McMullen, DN Brindley FEBS letters 588 (16), 2712-2727, 2014 | 162 | 2014 |
| Lipid phosphate phosphatases and their roles in mammalian physiology and pathology X Tang, MGK Benesch, DN Brindley Journal of lipid research 56 (11), 2048-2060, 2015 | 156 | 2015 |
| Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance RT Bekele, G Venkatraman, RZ Liu, X Tang, S Mi, MGK Benesch, ... Scientific reports 6 (1), 21164, 2016 | 134 | 2016 |
| Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice MGK Benesch, X Tang, T Maeda, A Ohhata, YY Zhao, BPC Kok, J Dewald, ... The FASEB Journal 28 (6), 2655-2666, 2014 | 131 | 2014 |
| Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate MGK Benesch, YY Zhao, JM Curtis, TPW McMullen, DN Brindley Journal of lipid research 56 (6), 1134-1144, 2015 | 128 | 2015 |
| Tumor‐induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression MGK Benesch, X Tang, J Dewald, WF Dong, JR Mackey, DG Hemmings, ... The FASEB Journal 29 (9), 3990-4000, 2015 | 106 | 2015 |
| Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment G Venkatraman, MGK Benesch, X Tang, J Dewald, TPW McMullen, ... The FASEB Journal 29 (3), 772-785, 2015 | 98 | 2015 |
| Epidemiology of signet ring cell adenocarcinomas MGK Benesch, A Mathieson Cancers 12 (6), 1544, 2020 | 93 | 2020 |
| Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo MGK Benesch, X Tang, G Venkatraman, RT Bekele, DN Brindley Journal of Biomedical Research 30 (4), 272, 2015 | 77 | 2015 |
| Coming of age for autotaxin and lysophosphatidate signaling: Clinical applications for preventing, detecting and targeting tumor-promoting inflammation MGK Benesch, ITK MacIntyre, TPW McMullen, DN Brindley Cancers 10 (3), 73, 2018 | 70 | 2018 |
| Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer MGK Benesch, YM Ko, X Tang, J Dewald, A Lopez-Campistrous, YY Zhao, ... Endocrine-related cancer 22 (4), 593-607, 2015 | 63 | 2015 |
| Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice [S] X Tang, MGK Benesch, J Dewald, YY Zhao, N Patwardhan, WL Santos, ... Journal of lipid research 55 (11), 2389-2400, 2014 | 59 | 2014 |
| Lysophosphatidate signaling: The tumor microenvironment’s new nemesis MGK Benesch, Z Yang, X Tang, G Meng, DN Brindley Trends in Cancer 3 (11), 748-752, 2017 | 54 | 2017 |
| Inhibition of autotaxin with GLPG1690 increases the efficacy of radiotherapy and chemotherapy in a mouse model of breast cancer X Tang, M Wuest, MGK Benesch, J Dufour, YY Zhao, JM Curtis, ... Molecular cancer therapeutics 19 (1), 63-74, 2020 | 49 | 2020 |
| Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy G Meng, X Tang, Z Yang, MGK Benesch, A Marshall, D Murray, ... The FASEB Journal 31 (9), 4064-4077, 2017 | 47 | 2017 |
| A calorimetric and spectroscopic comparison of the effects of lathosterol and cholesterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine … MGK Benesch, DA Mannock, RNAH Lewis, RN McElhaney Biochemistry 50 (46), 9982-9997, 2011 | 41 | 2011 |
| Role of adipose tissue-derived autotaxin, lysophosphatidate signaling, and inflammation in the progression and treatment of breast cancer DN Brindley, X Tang, G Meng, MGK Benesch International journal of molecular sciences 21 (16), 5938, 2020 | 38 | 2020 |
| A comparative calorimetric study of the effects of cholesterol and the plant sterols campesterol and brassicasterol on the thermotropic phase behavior of … MGK Benesch, RN McElhaney Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (7), 1941-1949, 2014 | 37 | 2014 |
| Role of the autotaxin–lysophosphatidate axis in the development of resistance to cancer therapy X Tang, MGK Benesch, DN Brindley Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 35 | 2020 |
| Autotaxin and breast cancer: Towards overcoming treatment barriers and sequelae MGK Benesch, X Tang, DN Brindley Cancers 12 (2), 374, 2020 | 35 | 2020 |
Todd McMullenUniversity of AlbertaVerified email at ualberta.ca