Mechanisms of transcriptional regulation by p53 KD Sullivan, MD Galbraith, Z Andrysik, JM Espinosa Cell Death & Differentiation 25 (1), 133-143, 2018 | 498 | 2018 |
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms MA Allen, Z Andrysik, VL Dengler, HS Mellert, A Guarnieri, JA Freeman, ... Elife 3, e02200, 2014 | 280 | 2014 |
Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover BE Fitzwalter, CG Towers, KD Sullivan, Z Andrysik, M Hoh, M Ludwig, ... Developmental cell 44 (5), 555-565. e3, 2018 | 201 | 2018 |
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ... Genome research 27 (10), 1645-1657, 2017 | 151 | 2017 |
Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels J Thorburn, Z Andrysik, L Staskiewicz, J Gump, P Maycotte, A Oberst, ... Cell reports 7 (1), 45-52, 2014 | 134 | 2014 |
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus Z Andrysik, WZ Bernstein, L Deng, DL Myer, YQ Li, JA Tischfield, ... Nucleic acids research 38 (9), 2931-2943, 2010 | 120 | 2010 |
Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic … Z Andrysík, J Vondráček, S Marvanová, M Ciganek, J Neča, K Pěnčíková, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 714 (1 …, 2011 | 103 | 2011 |
CDK8 kinase activity promotes glycolysis MD Galbraith, Z Andrysik, A Pandey, M Hoh, EA Bonner, AA Hill, ... Cell reports 21 (6), 1495-1506, 2017 | 93 | 2017 |
The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells Z Andrysík, J Vondráček, M Machala, P Krčmář, L Švihálková-Šindlerová, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 615 (1 …, 2007 | 92 | 2007 |
Transcriptional responses to IFN-γ require mediator kinase-dependent pause release and mechanistically distinct CDK8 and CDK19 functions I Steinparzer, V Sedlyarov, JD Rubin, K Eislmayr, MD Galbraith, ... Molecular cell 76 (3), 485-499. e8, 2019 | 79 | 2019 |
A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation Z Andrysik, J Kim, AC Tan, JM Espinosa Cell reports 3 (5), 1346-1354, 2013 | 74 | 2013 |
The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L AL Guarnieri, CG Towers, DJ Drasin, MUJ Oliphant, Z Andrysik, TJ Hotz, ... Oncogene 37 (28), 3879-3893, 2018 | 62 | 2018 |
Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response Z Andrysik, H Bender, MD Galbraith, JM Espinosa Nature communications 12 (1), 1375, 2021 | 52 | 2021 |
ΔNp63α suppresses TGFB2 expression and RHOA activity to drive cell proliferation in squamous cell carcinomas CG Abraham, MP Ludwig, Z Andrysik, A Pandey, M Joshi, MD Galbraith, ... Cell reports 24 (12), 3224-3236, 2018 | 45 | 2018 |
Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication Z Andrysík, J Procházková, M Kabátková, L Umannová, P Šimečková, ... Archives of toxicology 87, 491-503, 2013 | 45 | 2013 |
A DR4: tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX RE Henry, Z Andrysik, R París, MD Galbraith, JM Espinosa The EMBO journal 31 (5), 1266-1278, 2012 | 45 | 2012 |
7H-Dibenzo [c, g] carbazole and 5, 9-dimethyldibenzo [c, g] carbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial ‘stem-like’cells J Vondráček, L Švihálková-Šindlerová, K Pěnčíková, P Krčmář, Z Andrysík, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 596 (1 …, 2006 | 44 | 2006 |
Determination of Azidothymidine–an Antiproliferative and Virostatic Drug by Square‐Wave Voltammetry J Vacek, Z Andrysík, L Trnková, R Kizek Electroanalysis: An International Journal Devoted to Fundamental and …, 2004 | 41 | 2004 |
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model KA Waugh, R Minter, J Baxter, C Chi, MD Galbraith, KD Tuttle, ... Nature genetics 55 (6), 1034-1047, 2023 | 34 | 2023 |
Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis Z Andrysík, M Machala, K Chramostová, J Hofmanová, A Kozubík, ... Toxicology and applied pharmacology 211 (3), 198-208, 2006 | 34 | 2006 |