Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism F Chen, WAM Elgaher, M Winterhoff, K Büssow, FH Waqas, E Graner, ... Nature Metabolism 4 (5), 534-546, 2022 | 94 | 2022 |
Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis F Chen, P Lukat, AA Iqbal, K Saile, V Kaever, J van den Heuvel, ... Proceedings of the National Academy of Sciences 116 (41), 20644-20654, 2019 | 76 | 2019 |
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection A Sohail, AA Iqbal, N Sahini, F Chen, M Tantawy, SFH Waqas, ... PLoS pathogens 18 (1), e1010219, 2022 | 70 | 2022 |
Identification of essential genetic baculoviral elements for recombinant protein expression by transactivation in Sf21 insect cells M Bleckmann, M Schürig, FF Chen, ZZ Yen, N Lindemann, S Meyer, ... PLoS One 11 (3), e0149424, 2016 | 33 | 2016 |
Establishment, validation, and initial application of a sensitive LC-MS/MS assay for quantification of the naturally occurring isomers itaconate, mesaconate, and citraconate M Winterhoff, F Chen, N Sahini, T Ebensen, M Kuhn, V Kaever, H Bähre, ... Metabolites 11 (5), 270, 2021 | 21 | 2021 |
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction S Franz, F Pott, T Zillinger, C Schüler, S Dapa, C Fischer, V Passos, ... Life Science Alliance 4 (7), 2021 | 17 | 2021 |
Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1 F Chen, I Yalcin, M Zhao, C Chen, W Blankenfeldt, F Pessler, K Büssow Scientific Reports 13 (1), 10360, 2023 | 6 | 2023 |
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment F Chen, B Dowerg, T Cordes Current Opinion in Biotechnology 84, 102996, 2023 | 5 | 2023 |
Correction: Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection A Sohail, AA Iqbal, N Sahini, F Chen, M Tantawy, SFH Waqas, ... Plos Pathogens 18 (11), e1011002, 2022 | 4 | 2022 |
Mapping the Metabolic Niche of Citrate Metabolism and SLC13A5 F Chen, HF Willenbockel, T Cordes Metabolites 13 (3), 331, 2023 | 3 | 2023 |
Itaconate Isomers in Bread M Gruenwald, F Chen, H Bähre, F Pessler Antioxidants (Basel) 11 (7), 2022 | 3 | 2022 |
Citraconic acid and derivatives thereof for use as a medicament F Pessler, C Fangfang, M Winterhoff, K Büssow, W Blankenfeldt, A Hirsch, ... US Patent App. 18/556,649, 2024 | | 2024 |