Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate G Huyer, S Liu, J Kelly, J Moffat, P Payette, B Kennedy, G Tsaprailis, ... Journal of Biological Chemistry 272 (2), 843-851, 1997 | 1047 | 1997 |
Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein G Huyer, WF Piluek, Z Fansler, SG Kreft, M Hochstrasser, JL Brodsky, ... Journal of Biological Chemistry 279 (37), 38369-38378, 2004 | 340 | 2004 |
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein K Nakatsukasa, G Huyer, S Michaelis, JL Brodsky Cell 132 (1), 101-112, 2008 | 330 | 2008 |
Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome MP Mallampalli, G Huyer, P Bendale, MH Gelb, S Michaelis Proceedings of the National Academy of Sciences 102 (40), 14416-14421, 2005 | 249 | 2005 |
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. TA Vida, G Huyer, SD Emr The Journal of cell biology 121 (6), 1245-1256, 1993 | 204 | 1993 |
Yeast as a model system for studying endocytosis JD Shaw, KB Cummings, G Huyer, S Michaelis, B Wendland Experimental cell research 271 (1), 1-9, 2001 | 103 | 2001 |
A Striking Quality Control Subcompartment in Saccharomyces cerevisiae: The Endoplasmic Reticulum-associated Compartment G Huyer, GL Longsworth, DL Mason, MP Mallampalli, JM McCaffery, ... Molecular biology of the cell 15 (2), 908-921, 2004 | 100 | 2004 |
Affinity selection from peptide libraries to determine substrate specificity of protein tyrosine phosphatases G Huyer, J Kelly, J Moffat, R Zamboni, Z Jia, MJ Gresser, ... Analytical biochemistry 258 (1), 19-30, 1998 | 94 | 1998 |
Characterization of the porins of Campylobacter jejuni and Campylobacter coli and implications for antibiotic susceptibility WJ Page, G Huyer, M Huyer, EA Worobec Antimicrobial agents and chemotherapy 33 (3), 297-303, 1989 | 71 | 1989 |
Immune signalling: SHP-2 docks at multiple ports G Huyer, DR Alexander Current biology 9 (4), R129-R132, 1999 | 70 | 1999 |
The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation RJ Salmond, G Huyer, A Kotsoni, L Clements, DR Alexander The Journal of Immunology 175 (10), 6498-6508, 2005 | 59 | 2005 |
Direct determination of the sequence recognition requirements of the SH2 domains of SH-PTP2 G Huyer, ZM Li, M Adam, WR Huckle, C Ramachandran Biochemistry 34 (3), 1040-1049, 1995 | 57 | 1995 |
Saccharomyces cerevisiae a-Factor Mutants Reveal Residues Critical for Processing, Activity, and Export G Huyer, A Kistler, FJ Nouvet, CM George, ML Boyle, S Michaelis Eukaryotic Cell 5 (9), 1560-1570, 2006 | 56 | 2006 |
Synthesis of N‐Protected α‐Amino Acids from N‐(Benzyloxycarbonyl)‐L‐Serine via its β‐Lactone: Nα‐(Benzyloxycarbonyl)‐β‐(Pyrazol‐1‐yl)‐L‐Alanine Serine, N‐carboxy … SV Pansare, G Huyer, LD Arnold, JC Vederas Organic Syntheses 70, 1-1, 2003 | 55 | 2003 |
The internalization of yeast Ste6p follows an ordered series of events involving phosphorylation, ubiquitination, recognition and endocytosis KB Kelm, G Huyer, JC Huang, S Michaelis Traffic 5 (3), 165-180, 2004 | 46 | 2004 |
A Region within a Lumenal Loop of Saccharomyces cerevisiae Ycf1p Directs Proteolytic Processing and Substrate Specificity DL Mason, MP Mallampalli, G Huyer, S Michaelis Eukaryotic Cell 2 (3), 588-598, 2003 | 46 | 2003 |
The specificity of the N-terminal SH2 domain of SHP-2 is modified by a single point mutation G Huyer, C Ramachandran Biochemistry 37 (9), 2741-2747, 1998 | 36 | 1998 |
Diastereoselective alkylation of carbanions derived from 1, 3-oxathianes G Huyer, RN Young Tetrahedron letters 33 (6), 725-728, 1992 | 20 | 1992 |
A Two-Component Affinity Chromatography Purification ofHelix pomatiaArylsulfatase by Tyrosine Vanadate KI Skorey, NA Johnson, G Huyer, MJ Gresser Protein expression and purification 15 (2), 178-187, 1999 | 11 | 1999 |
Functional rescue of a misfolded eukaryotic ATP-binding cassette transporter by domain replacement RJ Louie, S Pagant, JY Youn, JJ Halliday, G Huyer, S Michaelis, EA Miller Journal of Biological Chemistry 285 (46), 36225-36234, 2010 | 6 | 2010 |