| DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A L Coelmont, X Hanoulle, U Chatterji, C Berger, J Snoeck, M Bobardt, ... PloS one 5 (10), e13687, 2010 | 222 | 2010 |
| Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B X Hanoulle, A Badillo, JM Wieruszeski, D Verdegem, I Landrieu, ... Journal of Biological Chemistry 284 (20), 13589-13601, 2009 | 201 | 2009 |
| Binding mechanisms of intrinsically disordered proteins: theory, simulation, and experiment L Mollica, LM Bessa, X Hanoulle, MR Jensen, M Blackledge, R Schneider Frontiers in molecular biosciences 3, 52, 2016 | 182 | 2016 |
| Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation C Smet-Nocca, M Broncel, JM Wieruszeski, C Tokarski, X Hanoulle, ... Molecular BioSystems 7 (5), 1420-1429, 2011 | 152 | 2011 |
| Glycan shielding and modulation of hepatitis C virus neutralizing antibodies M Lavie, X Hanoulle, J Dubuisson Frontiers in immunology 9, 910, 2018 | 122 | 2018 |
| Domain 3 of NS5A protein from the hepatitis C virus has intrinsic α-helical propensity and is a substrate of cyclophilin A D Verdegem, A Badillo, JM Wieruszeski, I Landrieu, A Leroy, ... Journal of Biological Chemistry 286 (23), 20441-20454, 2011 | 122 | 2011 |
| Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded X Hanoulle, D Verdegem, A Badillo, JM Wieruszeski, F Penin, G Lippens Biochemical and biophysical research communications 381 (4), 634-638, 2009 | 109 | 2009 |
| Tau aggregation in Alzheimer's disease: what role for phosphorylation? G Lippens, A Sillen, I Landrieu, L Amniai, N Sibille, P Barbier, A Leroy, ... Prion 1 (1), 21-25, 2007 | 91 | 2007 |
| Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria X Hanoulle, JM Wieruszeski, P Rousselot-Pailley, I Landrieu, C Locht, ... Journal of Antimicrobial Chemotherapy 58 (4), 768-772, 2006 | 63 | 2006 |
| The domain 2 of the HCV NS5A protein is intrinsically unstructured X Hanoulle, A Badillo, D Verdegem, F Penin, G Lippens Protein and peptide letters 17 (8), 1012-1018, 2010 | 60 | 2010 |
| Monitoring of the ethionamide pro-drug activation in mycobacteria by 1H high resolution magic angle spinning NMR X Hanoulle, JM Wieruszeski, P Rousselot-Pailley, I Landrieu, AR Baulard, ... Biochemical and biophysical research communications 331 (2), 452-458, 2005 | 60 | 2005 |
| Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025 I Landrieu, X Hanoulle, F Bonachera, A Hamel, N Sibille, Y Yin, ... Biochemistry 49 (22), 4679-4686, 2010 | 49 | 2010 |
| Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment C Danis, E Dupré, O Zejneli, R Caillierez, A Arrial, S Bégard, ... Molecular Therapy 30 (4), 1484-1499, 2022 | 47 | 2022 |
| Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner F Eysert, A Coulon, E Boscher, AC Vreulx, A Flaig, T Mendes, S Hughes, ... Molecular psychiatry 26 (10), 5592-5607, 2021 | 45 | 2021 |
| Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5A C Rosnoblet, B Fritzinger, D Legrand, H Launay, JM Wieruszeski, ... Journal of Biological Chemistry 287 (53), 44249-44260, 2012 | 44 | 2012 |
| Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry V Dehennaut, X Hanoulle, JF Bodart, JP Vilain, JC Michalski, I Landrieu, ... Biochemical and biophysical research communications 369 (2), 539-546, 2008 | 44 | 2008 |
| Structural analysis of Escherichia coli OpgG, a protein required for the biosynthesis of osmoregulated periplasmic glucans X Hanoulle, E Rollet, B Clantin, I Landrieu, C Ödberg-Ferragut, G Lippens, ... Journal of molecular biology 342 (1), 195-205, 2004 | 43 | 2004 |
| A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes X Hanoulle, J Van Damme, A Staes, L Martens, M Goethals, ... Journal of proteome research 5 (12), 3438-3445, 2006 | 42 | 2006 |
| Identification of novel functions for hepatitis C virus envelope glycoprotein E1 in virus entry and assembly JG Haddad, Y Rouillé, X Hanoulle, V Descamps, M Hamze, F Dabboussi, ... Journal of Virology 91 (8), 10.1128/jvi. 00048-17, 2017 | 41 | 2017 |
| Proline conformation in a functional tau fragment P Ahuja, FX Cantrelle, I Huvent, X Hanoulle, J Lopez, C Smet, ... Journal of molecular biology 428 (1), 79-91, 2016 | 39 | 2016 |