| Peripheral cannabinoid receptor, CB2, regulates bone mass O Ofek, M Karsak, N Leclerc, M Fogel, B Frenkel, K Wright, J Tam, ... Proceedings of the National Academy of Sciences 103 (3), 696-701, 2006 | 688 | 2006 |
| Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity J Tam, VK Vemuri, J Liu, S Bátkai, B Mukhopadhyay, G Godlewski, ... The Journal of clinical investigation 120 (8), 2953-2966, 2010 | 535 | 2010 |
| Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes T Jourdan, G Godlewski, R Cinar, A Bertola, G Szanda, J Liu, J Tam, ... Nature medicine 19 (9), 1132-1140, 2013 | 413 | 2013 |
| Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance J Tam, R Cinar, J Liu, G Godlewski, D Wesley, T Jourdan, G Szanda, ... Cell metabolism 16 (2), 167-179, 2012 | 375 | 2012 |
| Depression induces bone loss through stimulation of the sympathetic nervous system R Yirmiya, I Goshen, A Bajayo, T Kreisel, S Feldman, J Tam, V Trembovler, ... Proceedings of the National Academy of Sciences 103 (45), 16876-16881, 2006 | 292 | 2006 |
| Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span M Grunewald, S Kumar, H Sharife, E Volinsky, A Gileles-Hillel, T Licht, ... Science 373 (6554), eabc8479, 2021 | 237 | 2021 |
| The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling J Tam, V Trembovler, V Di Marzo, S Petrosino, G Leo, A Alexandrovich, ... The FASEB journal 22 (1), 285-294, 2008 | 237 | 2008 |
| Endocannabinoids in liver disease J Tam, J Liu, B Mukhopadhyay, R Cinar, G Godlewski, G Kunos Hepatology 53 (1), 346-355, 2011 | 232 | 2011 |
| Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice J Liu, L Zhou, K Xiong, G Godlewski, B Mukhopadhyay, J Tam, S Yin, ... Gastroenterology 142 (5), 1218-1228. e1, 2012 | 193 | 2012 |
| Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling J Tam, O Ofek, E Fride, C Ledent, Y Gabet, R Müller, A Zimmer, K Mackie, ... Molecular pharmacology 70 (3), 786-792, 2006 | 186 | 2006 |
| Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides R Cinar, G Godlewski, J Liu, J Tam, T Jourdan, B Mukhopadhyay, ... Hepatology 59 (1), 143-153, 2014 | 174 | 2014 |
| Endocannabinoids and the regulation of bone metabolism I Bab, O Ofek, J Tam, J Rehnelt, A Zimmer Journal of neuroendocrinology 20, 69-74, 2008 | 170 | 2008 |
| Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet S Srivastava, Y Kashiwaya, MT King, U Baxa, J Tam, G Niu, X Chen, ... The FASEB Journal 26 (6), 2351, 2012 | 149 | 2012 |
| Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy T Jourdan, G Szanda, AZ Rosenberg, J Tam, BJ Earley, G Godlewski, ... Proceedings of the National Academy of Sciences 111 (50), E5420-E5428, 2014 | 141 | 2014 |
| Lower circulating endocannabinoid levels in children with autism spectrum disorder A Aran, M Eylon, M Harel, L Polianski, A Nemirovski, S Tepper, ... Molecular autism 10, 1-11, 2019 | 133 | 2019 |
| miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression G Hanin, N Yayon, Y Tzur, R Haviv, ER Bennett, S Udi, ... Gut 67 (6), 1124-1134, 2018 | 127 | 2018 |
| The case for peripheral CB1 receptor blockade in the treatment of visceral obesity and its cardiometabolic complications G Kunos, J Tam British journal of pharmacology 163 (7), 1423-1431, 2011 | 125 | 2011 |
| Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver B Mukhopadhyay, R Cinar, S Yin, J Liu, J Tam, G Godlewski, ... Proceedings of the National Academy of Sciences 108 (15), 6323-6328, 2011 | 110 | 2011 |
| Metabolic circuit involving free fatty acids, microRNA 122, and triglyceride synthesis in liver and muscle tissues C Chai, M Rivkin, L Berkovits, A Simerzin, E Zorde-Khvalevsky, ... Gastroenterology 153 (5), 1404-1415, 2017 | 108 | 2017 |
| Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects G Godlewski, SO Alapafuja, S Bátkai, SP Nikas, R Cinar, L Offertáler, ... Chemistry & biology 17 (11), 1256-1266, 2010 | 101 | 2010 |
George KunosScientific Director, NIAAA/NIHVerified email at nih.gov
