Enteric defensins are essential regulators of intestinal microbial ecology NH Salzman, K Hung, D Haribhai, H Chu, J Karlsson-Sjöberg, E Amir, ... Nature immunology 11 (1), 76-82, 2010 | 1370 | 2010 |
Reduced Paneth cell α-defensins in ileal Crohn's disease J Wehkamp, NH Salzman, E Porter, S Nuding, M Weichenthal, RE Petras, ... Proceedings of the National Academy of Sciences 102 (50), 18129-18134, 2005 | 1335 | 2005 |
Innate immune recognition of the microbiota promotes host-microbial symbiosis H Chu, SK Mazmanian Nature immunology 14 (7), 668-675, 2013 | 659 | 2013 |
Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease H Chu, A Khosravi, IP Kusumawardhani, AHK Kwon, AC Vasconcelos, ... Science 352 (6289), 1116-1120, 2016 | 656 | 2016 |
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine M Raffatellu, MD George, Y Akiyama, MJ Hornsby, SP Nuccio, TA Paixao, ... Cell host & microbe 5 (5), 476-486, 2009 | 588 | 2009 |
Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets H Chu, M Pazgier, G Jung, SP Nuccio, PA Castillo, MF De Jong, ... Science 337 (6093), 477-481, 2012 | 445 | 2012 |
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis C Ramakrishna, M Kujawski, H Chu, L Li, SK Mazmanian, EM Cantin Nature communications 10 (1), 2153, 2019 | 248 | 2019 |
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity RH Mills, PS Dulai, Y Vázquez-Baeza, C Sauceda, N Daniel, RR Gerner, ... Nature microbiology 7 (2), 262-276, 2022 | 229 | 2022 |
Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues J Wehkamp, H Chu, B Shen, RW Feathers, RJ Kays, SK Lee, CL Bevins FEBS letters 580 (22), 5344-5350, 2006 | 215 | 2006 |
Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine I Godinez, M Raffatellu, H Chu, TA Paixao, T Haneda, RL Santos, ... Infection and immunity 77 (1), 387-398, 2009 | 202 | 2009 |
Genetic factors and the intestinal microbiome guide development of microbe-based therapies for inflammatory bowel diseases LJ Cohen, JH Cho, D Gevers, H Chu Gastroenterology 156 (8), 2174-2189, 2019 | 194 | 2019 |
Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires Y Yang, C Wang, Q Yang, AB Kantor, H Chu, EEB Ghosn, G Qin, ... Elife 4, e09083, 2015 | 149 | 2015 |
Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment S Mukherjee, CL Partch, RE Lehotzky, CV Whitham, H Chu, CL Bevins, ... Journal of Biological Chemistry 284 (8), 4881-4888, 2009 | 116 | 2009 |
The capsule encoding the viaB locus reduces interleukin-17 expression and mucosal innate responses in the bovine intestinal mucosa during infection with Salmonella enterica … M Raffatellu, RL Santos, D Chessa, RP Wilson, SE Winter, CA Rossetti, ... Infection and immunity 75 (9), 4342-4350, 2007 | 115 | 2007 |
Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract J Karlsson, K Pütsep, H Chu, RJ Kays, CL Bevins, M Andersson BMC immunology 9, 1-11, 2008 | 112 | 2008 |
Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection M Schunter, H Chu, TL Hayes, D McConnell, SS Crawford, PA Luciw, ... BMC complementary and alternative medicine 12, 1-15, 2012 | 83 | 2012 |
Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice GP Donaldson, WC Chou, AL Manson, P Rogov, T Abeel, J Bochicchio, ... Nature microbiology 5 (5), 746-756, 2020 | 74 | 2020 |
Strain diversity in the microbiome: Lessons from Bacteroides fragilis HC Carrow, LE Batachari, H Chu PLoS Pathogens 16 (12), e1009056, 2020 | 67 | 2020 |
Reverse metabolomics for the discovery of chemical structures from humans EC Gentry, SL Collins, M Panitchpakdi, P Belda-Ferre, AK Stewart, ... Nature 626 (7998), 419-426, 2024 | 66 | 2024 |
Bifidobacterium bifidum in a rat model of necrotizing enterocolitis: antimicrobial peptide and protein responses MA Underwood, A Kananurak, CF Coursodon, CK Adkins-Reick, H Chu, ... Pediatric research 71 (5), 546-551, 2012 | 58 | 2012 |