Changes in nutritional status impact immune cell metabolism and function Y Alwarawrah, K Kiernan, NJ MacIver Frontiers in immunology 9, 1055, 2018 | 534 | 2018 |
Fasnall, a selective FASN inhibitor, shows potent anti-tumor activity in the MMTV-Neu model of HER2+ breast cancer Y Alwarawrah, P Hughes, D Loiselle, DA Carlson, DB Darr, JL Jordan, ... Cell chemical biology 23 (6), 678-688, 2016 | 160 | 2016 |
Obesity-induced changes in T-cell metabolism are associated with impaired memory T-cell response to influenza and are not reversed with weight loss J Rebeles, WD Green, Y Alwarawrah, AG Nichols, W Eisner, K Danzaki, ... The Journal of Infectious Diseases 219 (10), 1652-1661, 2019 | 86 | 2019 |
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70 MK Howe, K Bodoor, DA Carlson, PF Hughes, Y Alwarawrah, DR Loiselle, ... Chemistry & biology 21 (12), 1648-1659, 2014 | 75 | 2014 |
Cellular fatty acid synthase is required for late stages of HIV-1 replication MM Kulkarni, AN Ratcliff, M Bhat, Y Alwarawrah, P Hughes, J Arcos, ... Retrovirology 14, 1-12, 2017 | 48 | 2017 |
Emerging mechanisms of obesity-associated immune dysfunction SR Shaikh, MA Beck, Y Alwarawrah, NJ MacIver Nature Reviews Endocrinology 20 (3), 136-148, 2024 | 42 | 2024 |
Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity Y Alwarawrah, AG Nichols, WD Green, W Eisner, K Kiernan, J Warren, ... International Journal of Obesity 44 (12), 2419-2429, 2020 | 38 | 2020 |
Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function K Kiernan, Y Alwarawrah, AG Nichols, K Danzaki, NJ MacIver Scientific reports 14 (1), 4331, 2024 | 11 | 2024 |
Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity K Kiernan, AG Nichols, Y Alwarawrah, NJ MacIver PLoS One 18 (6), e0286470, 2023 | 10 | 2023 |
Irgm1 regulates metabolism and function in T cell subsets Y Alwarawrah, K Danzaki, AG Nichols, BE Fee, C Bock, G Kucera, ... Scientific Reports 12 (1), 850, 2022 | 10 | 2022 |
Immune function in obesity Y Alwarawrah, NJ MacIver Pediatric obesity: etiology, pathogenesis and treatment, 363-378, 2018 | 5 | 2018 |
Inflammation and metabolism of influenza-stimulated peripheral blood mononuclear cells from adults with obesity following bariatric surgery WD Green, Y Alwarawrah, AE Al-Shaer, Q Shi, M Armstrong, J Manke, ... The Journal of Infectious Diseases 227 (1), 92-102, 2023 | 4 | 2023 |
Overcoming lapatinib resistance by the fatty acid synthase inhibitor HS-106 Y Alwarawrah, P Hughes, R Safi, DP McDonnell, NL Spector, ... Cancer Research 75 (15_Supplement), 2703-2703, 2015 | 4 | 2015 |
Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages BE Fee, LR Fee, M Menechella, B Affeldt, AR Sprouse, A Bounini, ... Journal of Biological Chemistry 300 (11), 107883, 2024 | 1 | 2024 |
Fatty acid synthase inhibitors J Kwiek, T Haystead, P Hughes, Y Alwarawrah US Patent 10,966,981, 2021 | 1 | 2021 |
Fatty acid synthase inhibitors J KWIEK, T Haystead, P Hughes, Y ALWARAWRAH | 1 | 2017 |
Alveolar and Bone Marrow-derived Macrophages Differ in Metabolism and Glutamine Utilization CL Vigeland, JD Link, HS Beggs, Y Alwarawrah, BM Ehrmann, H Dang, ... American Journal of Respiratory Cell and Molecular Biology, 2024 | | 2024 |
Glutamine-mediated Changes in the Activity of Alveolar and Bone Marrow-derived Macrophages CL Vigeland, JD Link, Y Alwarawrah, CM Doerschuk A31. IMMUNE CELL MOLECULAR ACTIVATION SWITCH IN LUNG INJURY AND INFLAMMATION …, 2024 | | 2024 |
Metformin treatment of CD8 T cells decreases pro-inflammatory cytokine production and shifts their metabolic state toward oxidative metabolism CT Molloy, Y Alwarawrah, N MacIver The Journal of Immunology 210 (1_Supplement), 66.12-66.12, 2023 | | 2023 |
OR12-2 Obesity Induces Changes in T Cell Metabolism and Function Y Alwarawrah, A Nichols, W Eisner, N MacIver Journal of the Endocrine Society 3 (Supplement_1), OR12-2, 2019 | | 2019 |