Charlotte M. Miton

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Nobuhiko TokurikiUniversity of British ColumbiaVerified email at msl.ubc.ca
Florian HollfelderUniversity of CambridgeVerified email at cam.ac.uk
Balint KintsesHCEMM - BRCVerified email at brc.hu
Marko HyvönenUniversity of CambridgeVerified email at cam.ac.uk
Pierre-Yves ColinLabGeniusVerified email at labgeni.us
Fabrice GielenUniversity of ExeterVerified email at exeter.ac.uk
Dick B. JanssenUniversity of GroningenVerified email at rug.nl
Diego MorgaviINRAEVerified email at clermont.inra.fr
Colin JacksonProfessor, Research School of Chemistry, Australian National UniversityVerified email at anu.edu.au
Shina Caroline Lynn KamerlinGeorgia Institute of TechnologyVerified email at gatech.edu
Florian BaierRiver Ecosystems Laboratory at EPFL in Sion, ValaisVerified email at epfl.ch
Nansook HongVerified email at anu.edu.au
Janine CoppUniversity of British ColumbiaVerified email at msl.ubc.ca
Fernanda DuarteUniversity of OxfordVerified email at chem.ox.ac.uk
Stefanie JonasETH ZurichVerified email at mol.biol.ethz.ch

Charlotte M. Miton

University of British Columbia

Verified email at msl.ubc.ca - Homepage

Biochemistry Molecular evolution


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Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics PY Colin, B Kintses, F Gielen, CM Miton, G Fischer, MF Mohamed, ... Nature communications 6 (1), 10008, 2015	430	2015
How mutational epistasis impairs predictability in protein evolution and design CM Miton, N Tokuriki Protein Science 25 (7), 1260-1272, 2016	205	2016
A mechanistic view of enzyme evolution G Yang, CM Miton, N Tokuriki Protein Science 29 (8), 1724-1747, 2020	68	2020
Epistasis and intramolecular networks in protein evolution CM Miton, K Buda, N Tokuriki Current Opinion in Structural Biology 69 (August 2021), 160-168, 2021	66	2021
Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes F Baier, N Hong, G Yang, A Pabis, CM Miton, A Barrozo, PD Carr, ... Elife 8, e40789, 2019	47	2019
Mechanistic understanding enables the rational design of salicylanilide combination therapies for Gram-negative infections JN Copp, D Pletzer, AS Brown, J Van der Heijden, CM Miton, RJ Edgar, ... MBio 11 (5), 10.1128/mbio. 02068-20, 2020	38	2020
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset CM Miton, S Jonas, G Fischer, F Duarte, MF Mohamed, B van Loo, ... Proceedings of the National Academy of Sciences 115 (31), E7293-E7302, 2018	36	2018
Statistical analysis of mutational epistasis to reveal intramolecular interaction networks in proteins CM Miton, JZ Chen, K Ost, DW Anderson, N Tokuriki Methods in Enzymology 643, 243-280, 2020	25	2020
Insertions and deletions (indels): a missing piece of the protein engineering jigsaw CM Miton, N Tokuriki Biochemistry 62 (2), 148-157, 2022	24	2022
Molecular determinants of protein evolvability K Buda, CM Miton, XC Fan, N Tokuriki Trends in Biochemical Sciences 48 (9), 751-760, 2023	20	2023
Pervasive epistasis exposes intramolecular networks in adaptive enzyme evolution K Buda, CM Miton, N Tokuriki Nature Communications 14 (1), 8508, 2023	16*	2023
Leveraging ancestral sequence reconstruction for protein representation learning DS Matthews, MA Spence, AC Mater, J Nichols, SB Pulsford, M Sandhu, ... Nature Machine Intelligence 6 (12), 1542-1555, 2024	4	2024
Origin Of Evolutionary Bifurcation In An Enzyme CM Miton, EC Campbell, JA Kaczmarski, F Feixas, A Romero-Rivera, ... bioRxiv, 2023.11. 25.568631, 2023	2	2023

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