| Structural basis of BMP signalling inhibition by the cystine knot protein Noggin J Groppe, J Greenwald, E Wiater, J Rodriguez-Leon, AN Economides, ... Nature 420 (6916), 636-642, 2002 | 695 | 2002 |
| Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1 FS Kaplan, M Xu, P Seemann, JM Connor, DL Glaser, L Carroll, P Delai, ... Human mutation 30 (3), 379-390, 2009 | 495 | 2009 |
| Fibrodysplasia ossificans progressiva FS Kaplan, M Le Merrer, DL Glaser, RJ Pignolo, RE Goldsby, ... Best practice & research Clinical rheumatology 22 (1), 191-205, 2008 | 425 | 2008 |
| The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly J Greenwald, J Groppe, P Gray, E Wiater, W Kwiatkowski, W Vale, S Choe Molecular cell 11 (3), 605-617, 2003 | 365 | 2003 |
| Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding J Groppe, CS Hinck, P Samavarchi-Tehrani, C Zubieta, JP Schuermann, ... Molecular cell 29 (2), 157-168, 2008 | 346 | 2008 |
| The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system K Guillemin, J Groppe, K Dücker, R Treisman, E Hafen, M Affolter, ... Development 122 (5), 1353-1362, 1996 | 207 | 1996 |
| Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice X Wang, S Wang, C Li, T Gao, Y Liu, A Rangiani, Y Sun, J Hao, A George, ... PLoS genetics 8 (5), e1002708, 2012 | 188 | 2012 |
| The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered J Montagne, J Groppe, K Guillemin, MA Krasnow, WJ Gehring, M Affolter Development 122 (9), 2589-2597, 1996 | 162 | 1996 |
| Cellular hypoxia promotes heterotopic ossification by amplifying BMP signaling H Wang, C Lindborg, V Lounev, JH Kim, R McCarrick‐Walmsley, M Xu, ... Journal of Bone and Mineral Research 31 (9), 1652-1665, 2016 | 146 | 2016 |
| Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein J Groppe, J Greenwald, E Wiater, J Rodriguez-Leon, AN Economides, ... JBJS 85 (suppl_3), 52-58, 2003 | 132 | 2003 |
| Intricacies of BMP receptor assembly J Nickel, W Sebald, JC Groppe, TD Mueller Cytokine & growth factor reviews 20 (5-6), 367-377, 2009 | 131 | 2009 |
| The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development M Affolter, J Montagne, U Walldorf, J Groppe, U Kloter, M LaRosa, ... Development 120 (4), 743-753, 1994 | 127 | 1994 |
| Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN P Seemann, A Brehm, J König, C Reissner, S Stricker, P Kuss, J Haupt, ... PLoS genetics 5 (11), e1000747, 2009 | 123 | 2009 |
| Functional modeling of the ACVR1 (R206H) mutation in FOP JC Groppe, EM Shore, FS Kaplan Clinical Orthopaedics and Related Research® 462, 87-92, 2007 | 117 | 2007 |
| Assembly of TβRI: TβRII: TGFβ ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent JE Zúñiga, JC Groppe, Y Cui, CS Hinck, V Contreras-Shannon, ... Journal of molecular biology 354 (5), 1052-1068, 2005 | 114 | 2005 |
| Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP) FS Kaplan, Q Shen, V Lounev, P Seemann, J Groppe, T Katagiri, ... Journal of bone and mineral metabolism 26, 521-530, 2008 | 108 | 2008 |
| Expression, purification, and characterization of a soluble form of the first extracellular domain of the human type 1 corticotropin releasing factor receptor MH Perrin, WH Fischer, KS Kunitake, AG Craig, SC Koerber, LA Cervini, ... Journal of Biological Chemistry 276 (34), 31528-31534, 2001 | 99 | 2001 |
| In vitro analyses of the dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP JC Groppe, J Wu, EM Shore, FS Kaplan Cells Tissues Organs 194 (2-4), 291-295, 2011 | 87 | 2011 |
| Preliminary Characterization of the Transcriptional and Translational Products of the Saccharomyces cerevisiae Cell Division Cycle Gene CDC28 SI Reed, J Ferguson, JC Groppe Molecular and cellular biology 2 (4), 412-425, 1982 | 85 | 1982 |
| Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9 Y Wang, JC Groppe, J Wu, T Ogawa, G Mues, RN D'Souza, H Kapadia Human molecular genetics 18 (15), 2863-2874, 2009 | 70 | 2009 |
Markus AffolterProfessor of Cell Biology, Biozentrum University of BaselVerified email at unibas.ch