Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance K Kabayama, T Sato, K Saito, N Loberto, A Prinetti, S Sonnino, M Kinjo, ... Proceedings of the National Academy of Sciences 104 (34), 13678-13683, 2007 | 454 | 2007 |
Ganglioside GM3 participates in the pathological conditions of insulin resistance S Tagami, J Inokuchi, K Kabayama, H Yoshimura, F Kitamura, S Uemura, ... Journal of Biological Chemistry 277 (5), 3085-3092, 2002 | 438 | 2002 |
TNFα-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3 K Kabayama, T Sato, F Kitamura, S Uemura, BW Kang, Y Igarashi, ... Glycobiology 15 (1), 21-29, 2005 | 214 | 2005 |
Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti M Yoshikawa, S Go, K Takasaki, Y Kakazu, M Ohashi, M Nagafuku, ... Proceedings of the National Academy of Sciences 106 (23), 9483-9488, 2009 | 160 | 2009 |
Reduction of glycosphingolipid levels in lipid rafts affects the expression state and function of glycosylphosphatidylinositol-anchored proteins but does not impair signal … M Nagafuku, K Kabayama, D Oka, A Kato, S Tani-Ichi, Y Shimada, ... Journal of Biological Chemistry 278 (51), 51920-51927, 2003 | 71 | 2003 |
Biology of GM3 ganglioside J Inokuchi, K Inamori, K Kabayama, M Nagafuku, S Uemura, S Go, ... Progress in molecular biology and translational science 156, 151-195, 2018 | 61 | 2018 |
Development of a new inhibitor of glucosylceramide synthase M Jimbo, K Yamagishi, T Yamaki, K Nunomura, K Kabayama, Y Igarashi, ... The journal of biochemistry 127 (3), 485-491, 2000 | 61 | 2000 |
Structure and function of lipid rafts in human activated T cells S Tani-ichi, K Maruyama, N Kondo, M Nagafuku, K Kabayama, J Inokuchi, ... International immunology 17 (6), 749-758, 2005 | 60 | 2005 |
Lipopolysaccharide from Gut‐Associated Lymphoid‐Tissue‐Resident Alcaligenes faecalis: Complete Structure Determination and Chemical Synthesis of Its Lipid A A Shimoyama, F Di Lorenzo, H Yamaura, K Mizote, A Palmigiano, ... Angewandte Chemie 133 (18), 10111-10119, 2021 | 48 | 2021 |
Chemical modification of β-glucocerebrosidase inhibitor N-octyl-β-valienamine: synthesis and biological evaluation of N-alkanoyl and N-alkyl derivatives S Ogawa, Y Kobayashi, K Kabayama, M Jimbo, J Inokuchi Bioorganic & medicinal chemistry 6 (10), 1955-1962, 1998 | 46 | 1998 |
α‐Emitting cancer therapy using 211At‐AAMT targeting LAT1 K Kaneda‐Nakashima, ZJ Zhang, Y Manabe, A Shimoyama, K Kabayama, ... Cancer science 112 (3), 1132-1140, 2021 | 43 | 2021 |
Glycosphingolipid deficiency affects functional microdomain formation in Lewis lung carcinoma cells J Inokuchi, S Uemura, K Kabayama, Y Igarashi Glycoconjugate Journal 17, 239-245, 2000 | 43 | 2000 |
Dissociation of the insulin receptor from caveolae during TNFα-induced insulin resistance and its recovery by D-PDMP J Sekimoto, K Kabayama, K Gohara, J Inokuchi FEBS letters 586 (2), 191-195, 2012 | 40 | 2012 |
Development of α‐Gal–Antibody Conjugates to Increase Immune Response by Recruiting Natural Antibodies J Sianturi, Y Manabe, HS Li, LT Chiu, TC Chang, K Tokunaga, ... Angewandte Chemie 131 (14), 4574-4578, 2019 | 38 | 2019 |
Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy H Kato, X Huang, Y Kadonaga, D Katayama, K Ooe, A Shimoyama, ... Journal of Nanobiotechnology 19, 1-12, 2021 | 37 | 2021 |
Homeostatic and pathogenic roles of GM 3 ganglioside molecular species in TLR 4 signaling in obesity H Kanoh, T Nitta, S Go, K Inamori, L Veillon, W Nihei, M Fujii, ... The EMBO journal 39 (12), e101732, 2020 | 37 | 2020 |
Convenient synthesis and evaluation of glycosidase inhibitory activity of α-and β-galactose-type valienamines, and some N-alkyl derivatives S Ogawa, Y Sakata, N Ito, M Watanabe, K Kabayama, M Itoh, T Korenaga Bioorganic & medicinal chemistry 12 (5), 995-1002, 2004 | 37 | 2004 |
Endogenously produced ganglioside GM3 endows etoposide and doxorubicin resistance by up-regulating Bcl-2 expression in 3LL Lewis lung carcinoma cells M Noguchi, K Kabayama, S Uemura, B Kang, M Saito, Y Igarashi, ... Glycobiology 16 (7), 641-650, 2006 | 36 | 2006 |
The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin‐1 Y Manabe, R Marchetti, Y Takakura, M Nagasaki, W Nihei, T Takebe, ... Angewandte Chemie International Edition 58 (51), 18697-18702, 2019 | 35 | 2019 |
Sialylation and sulfation of lactosylceramide distinctly regulate anchorage-independent growth, apoptosis, and gene expression in3LL Lewis lung carcinoma cells S Uemura, K Kabayama, M Noguchi, Y Igarashi, J Inokuchi Glycobiology 13 (3), 207-216, 2003 | 33 | 2003 |