| Ketones and lactate “fuel” tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism G Bonuccelli, A Tsirigos, D Whitaker-Menezes, S Pavlides, RG Pestell, ... Cell cycle 9 (17), 3506-3514, 2010 | 725 | 2010 |
| Stat3 promotes metastatic progression of prostate cancer J Abdulghani, L Gu, A Dagvadorj, J Lutz, B Leiby, G Bonuccelli, ... The American journal of pathology 172 (6), 1717-1728, 2008 | 319 | 2008 |
| Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production C Capparelli, C Guido, D Whitaker-Menezes, G Bonuccelli, R Balliet, ... Cell cycle 11 (12), 2285-2302, 2012 | 285 | 2012 |
| The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts G Bonuccelli, D Whitaker-Menezes, R Castello-Cros, S Pavlides, ... Cell cycle 9 (10), 1960-1971, 2010 | 270 | 2010 |
| The autophagic tumor stroma model of cancer or “battery-operated tumor growth” a simple solution to the autophagy paradox UE Martinez-Outschoorn, D Whitaker-Menezes, S Pavlides, B Chiavarina, ... Cell cycle 9 (21), 4297-4306, 2010 | 192 | 2010 |
| Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 down-regulation and RB tumor suppressor functional inactivation: implications for the response to hormonal therapy I Mercier, MC Casimiro, C Wang, AL Rosenberg, J Quong, A Minkeu, ... Cancer biology & therapy 7 (8), 1212-1225, 2008 | 174 | 2008 |
| Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins G Bonuccelli, F Sotgia, W Schubert, DS Park, PG Frank, SE Woodman, ... The American journal of pathology 163 (4), 1663-1675, 2003 | 159 | 2003 |
| TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell–matrix interactions on collagen KA Hotchkiss, CM Basile, SC Spring, G Bonuccelli, MP Lisanti, BI Terman Experimental cell research 305 (1), 133-144, 2005 | 151 | 2005 |
| Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells G Bonuccelli, S Avnet, G Grisendi, M Salerno, D Granchi, M Dominici, ... Oncotarget 5 (17), 7575, 2014 | 145 | 2014 |
| Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling R Lamb, G Bonuccelli, B Ozsvári, M Peiris-Pagès, M Fiorillo, DL Smith, ... Oncotarget 6 (31), 30453, 2015 | 143 | 2015 |
| Caveolin-1−/− null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts F Sotgia, F Del Galdo, MC Casimiro, G Bonuccelli, I Mercier, ... The American journal of pathology 174 (3), 746-761, 2009 | 140 | 2009 |
| ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis’ three sites of entry: implications for the pathogenesis of anthrax infection G Bonuccelli, F Sotgia, PG Frank, TM Williams, CJ De Almeida, ... American Journal of Physiology-Cell Physiology 288 (6), C1402-C1410, 2005 | 127 | 2005 |
| Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells F Sotgia, B Razani, G Bonuccelli, W Schubert, M Battista, H Lee, ... Molecular and cellular biology, 2002 | 113 | 2002 |
| Caveolin-1-Deficient Mice Show Defects in Innate Immunity and Inflammatory Immune Response during Salmonella enterica Serovar Typhimurium Infection FA Medina, CJ De Almeida, E Dew, J Li, G Bonuccelli, TM Williams, ... Infection and immunity 74 (12), 6665-6674, 2006 | 109 | 2006 |
| Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature G Bonuccelli, MC Casimiro, F Sotgia, C Wang, M Liu, S Katiyar, J Zhou, ... The American journal of pathology 174 (5), 1650-1662, 2009 | 106 | 2009 |
| Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs) EM De Francesco, G Bonuccelli, M Maggiolini, F Sotgia, MP Lisanti Oncotarget 8 (40), 67269, 2017 | 103 | 2017 |
| Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis SM Muehlbauer, TH Evering, G Bonuccelli, RC Squires, AW Ashton, ... Cell cycle 6 (6), 758-766, 2007 | 103 | 2007 |
| Tumor-activated mesenchymal stromal cells promote osteosarcoma stemness and migratory potential via IL-6 secretion M Cortini, A Massa, S Avnet, G Bonuccelli, N Baldini PloS one 11 (11), e0166500, 2016 | 100 | 2016 |
| Therapeutic potential of proteasome inhibition in Duchenne and Becker muscular dystrophies E Gazzerro, S Assereto, A Bonetto, F Sotgia, S Scarfì, A Pistorio, ... The American journal of pathology 176 (4), 1863-1877, 2010 | 100 | 2010 |
| Mitochondrial fission as a driver of stemness in tumor cells: mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling M Peiris-Pagès, G Bonuccelli, F Sotgia, MP Lisanti Oncotarget 9 (17), 13254, 2018 | 96 | 2018 |