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Hsueh-Yuan Chang
Hsueh-Yuan Chang
Other namesHY Chang
Senior Clinical Pharmacologist at Takeda Development Center Americas INC
Verified email at buffalo.edu
Title
Cited by
Cited by
Year
Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma
WH Chen, HY Liu, WC Lo, SC Wu, CH Chi, HY Chang, SH Hsiao, CH Wu, ...
Biomaterials 30 (29), 5523-5533, 2009
1752009
Antibody pharmacokinetics in rat brain determined using microdialysis
HY Chang, K Morrow, E Bonacquisti, WY Zhang, DK Shah
MAbs 10 (6), 843-853, 2018
732018
A translational platform PBPK model for antibody disposition in the brain
HY Chang, S Wu, G Meno-Tetang, DK Shah
Journal of pharmacokinetics and pharmacodynamics 46, 319-338, 2019
672019
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models
EA Chowdhury, G Meno-Tetang, HY Chang, S Wu, HW Huang, T Jamier, ...
Advanced Drug Delivery Reviews 170, 214-237, 2021
602021
Effect of size on solid tumor disposition of protein therapeutics
Z Li, Y Li, HP Chang, HY Chang, L Guo, DK Shah
Drug Metabolism and Disposition 47 (10), 1136-1145, 2019
442019
Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis
HY Chang, S Wu, Y Li, W Zhang, M Burrell, CI Webster, DK Shah
MAbs 13 (1), 1874121, 2021
342021
Effect of the size of protein therapeutics on brain pharmacokinetics following systematic administration
HY Chang, S Wu, Y Li, L Guo, Y Li, DK Shah
The AAPS journal 24 (3), 62, 2022
132022
Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central …
HY Chang, S Wu, EA Chowdhury, DK Shah
Journal of Pharmacokinetics and Pharmacodynamics 49 (3), 337-362, 2022
92022
Pharmacokinetics of monoclonal antibody and antibody fragments in the mouse eye following systemic administration
D Bussing, Z Li, Y Li, HP Chang, HY Chang, L Guo, A Verma, DK Shah
The AAPS Journal 23, 1-11, 2021
62021
Investigation of Antibody Pharmacokinetics in the Brain Following Intra-CNS Administration and Development of PBPK Model to Characterize the Data
S Wu, HY Chang, EA Chowdhury, HW Huang, DK Shah
The AAPS Journal 26 (2), 29, 2024
2024
Approaches towards prediction of CNS PK and PD
ECM Lange, HY Chang, D Shah
Drug Delivery to the Brain: Physiological Concepts, Methodologies and …, 2022
2022
Quantitative Investigation of Pharmacokinetics of Antibody-Based Therapeutics in the Central Nervous System
HY Chang
State University of New York at Buffalo, 2021
2021
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Articles 1–12