Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma WH Chen, HY Liu, WC Lo, SC Wu, CH Chi, HY Chang, SH Hsiao, CH Wu, ... Biomaterials 30 (29), 5523-5533, 2009 | 175 | 2009 |
Antibody pharmacokinetics in rat brain determined using microdialysis HY Chang, K Morrow, E Bonacquisti, WY Zhang, DK Shah MAbs 10 (6), 843-853, 2018 | 73 | 2018 |
A translational platform PBPK model for antibody disposition in the brain HY Chang, S Wu, G Meno-Tetang, DK Shah Journal of pharmacokinetics and pharmacodynamics 46, 319-338, 2019 | 67 | 2019 |
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models EA Chowdhury, G Meno-Tetang, HY Chang, S Wu, HW Huang, T Jamier, ... Advanced Drug Delivery Reviews 170, 214-237, 2021 | 60 | 2021 |
Effect of size on solid tumor disposition of protein therapeutics Z Li, Y Li, HP Chang, HY Chang, L Guo, DK Shah Drug Metabolism and Disposition 47 (10), 1136-1145, 2019 | 44 | 2019 |
Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis HY Chang, S Wu, Y Li, W Zhang, M Burrell, CI Webster, DK Shah MAbs 13 (1), 1874121, 2021 | 34 | 2021 |
Effect of the size of protein therapeutics on brain pharmacokinetics following systematic administration HY Chang, S Wu, Y Li, L Guo, Y Li, DK Shah The AAPS journal 24 (3), 62, 2022 | 13 | 2022 |
Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central … HY Chang, S Wu, EA Chowdhury, DK Shah Journal of Pharmacokinetics and Pharmacodynamics 49 (3), 337-362, 2022 | 9 | 2022 |
Pharmacokinetics of monoclonal antibody and antibody fragments in the mouse eye following systemic administration D Bussing, Z Li, Y Li, HP Chang, HY Chang, L Guo, A Verma, DK Shah The AAPS Journal 23, 1-11, 2021 | 6 | 2021 |
Investigation of Antibody Pharmacokinetics in the Brain Following Intra-CNS Administration and Development of PBPK Model to Characterize the Data S Wu, HY Chang, EA Chowdhury, HW Huang, DK Shah The AAPS Journal 26 (2), 29, 2024 | | 2024 |
Approaches towards prediction of CNS PK and PD ECM Lange, HY Chang, D Shah Drug Delivery to the Brain: Physiological Concepts, Methodologies and …, 2022 | | 2022 |
Quantitative Investigation of Pharmacokinetics of Antibody-Based Therapeutics in the Central Nervous System HY Chang State University of New York at Buffalo, 2021 | | 2021 |