| Network pharmacology: curing causal mechanisms instead of treating symptoms C Nogales, ZM Mamdouh, M List, C Kiel, AI Casas, HHHW Schmidt Trends in Pharmacological Sciences 43 (2), 136-150, 2022 | 611 | 2022 |
| On the clinical pharmacology of reactive oxygen species AI Casas, C Nogales, HAM Mucke, A Petraina, A Cuadrado, AI Rojo, ... Pharmacological reviews 72 (4), 801-828, 2020 | 104 | 2020 |
| Network medicine for disease module identification and drug repurposing with the NeDRex platform S Sadegh, J Skelton, E Anastasi, J Bernett, DB Blumenthal, G Galindez, ... Nature Communications 12 (1), 6848, 2021 | 93 | 2021 |
| NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype MH Elbatreek, S Sadegh, E Anastasi, E Guney, C Nogales, T Kacprowski, ... PLoS biology 18 (11), e3000885, 2020 | 42 | 2020 |
| Cyclic GMP modulating drugs in cardiovascular diseases: Mechanism-based network pharmacology A Petraina, C Nogales, T Krahn, H Mucke, TF Lüscher, R Fischmeister, ... Cardiovascular research 118 (9), 2085-2102, 2022 | 37 | 2022 |
| Cancer driver drug interaction explorer M Hartung, E Anastasi, ZM Mamdouh, C Nogales, HHHW Schmidt, ... Nucleic acids research 50 (W1), W138-W144, 2022 | 20 | 2022 |
| Network medicine-based unbiased disease modules for drug and diagnostic target identification in ROSopathies C Nogales, AGB Grønning, S Sadegh, J Baumbach, HHHW Schmidt Reactive Oxygen Species: Network Pharmacology and Therapeutic Applications …, 2021 | 9 | 2021 |
| NeDRex-an integrative and interactive network medicine platform for drug repurposing S Sadegh, J Skelton, E Anastasi, DB Blumenthal, A Maier, G Galindez, ... RExPO22, 2022 | 3 | 2022 |
| Nitrative signaling into cardiac lactate dehydrogenase Trp324 modulates active site loop mobility and activity under metabolic stress C Nogales, J Frijhoff, D Thoenges, RB Sessions, A Sickmann, ... bioRxiv, 348789, 2019 | 3* | 2019 |
| Diagnostics for Repurposed Drugs RP Loewe, C Nogales, V Olexiouk, R Schmidt, T Krahn DrugRxiv, 2024 | 1 | 2024 |
| Network pharmacology drug repurposing strategy for neurovascular diseases AI Casas, C Nogales, MH Elbatreek, S Sadegh, E Anastasi, J Skelton, ... RExPO22, 2022 | 1 | 2022 |
| Toward Mechanism‐based Therapies and Network Pharmacology C Nogales, Z Piper, Z Mamdouh, MP Pachado Polypharmacology: Strategies for Multi‐Target Drug Discovery, 97-108, 2025 | | 2025 |
| NeDRex-Web: An Interactive Web Tool for Drug Repurposing by Exploring Heterogeneous Molecular Networks A Maier, M Rafiei, E Anastasi, O Zolotareva, J Skelton, ML Elkjaer, ... 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2024 | | 2024 |
| Systems and network approaches to precision medicine and healthcare EL Kurnat-Thoma, C Nogales, S Vasudevan Frontiers in Molecular Biosciences 11, 1463962, 2024 | | 2024 |
| NOS recoupling with L-citrulline, folate, and vericiguat in a NOX5-positive subgroup of HFpEF patients: A Phase IIa proof-of-concept trial R De la Espriella, C Nogales, AE Casas, B Frank, HAM Mucke, A Petraina, ... cGMP: Generators, Effectors and Therapeutic Implications Conference, 2024 | | 2024 |
| Mechanistic endotyping of the ROS/cGMP disease cluster in the Estonian Biobank C Nogales Calvo, J Kronberg, A Petraina, MP Pachado, M Nelis, L Milani, ... RExPO23 Conference, 2023 | | 2023 |
| Mechanistic endotyping of the ROS/cGMP disease cluster in the Estonian Biobank C Nogales Calvo, J Kronberg, A Petraina, MP Pachado, M Nelis, L Milani, ... RExPO23 Conference, 2023 | | 2023 |
| Re-Addressing Dementia by Network Medicine and Mechanism-Based Molecular Endotypes M Pacheco Pachado, AI Casas, MH Elbatreek, C Nogales, E Guney, ... Journal of Alzheimer's Disease, 1-10, 2023 | | 2023 |
| Why the way we define diseases prevents innovation and precision medicine ZM Mamdouh, E Anastasi, AA Hassan, J Boltze, MH Elbatreek, C Nogales, ... DrugRxiv, 2023 | | 2023 |
| From phenotype to endotype: preclinical validation of ROS-cGMPopathies in the Estonian Biobank C Nogales, J Kronberg, A Petraina, MP Pachado, J Weerts, AB Aizpurua, ... JOURNAL OF TRANSLATIONAL MEDICINE 21 (SUPPL 1), 2023 | | 2023 |
Harald H.H.W. SchmidtProfessor & Chair of Pharmacology and Personalised Medicine, University of MaastrichtVerified email at maastrichtuniversity.nl
