Coumarin: A natural, privileged and versatile scaffold for bioactive compounds A Stefanachi, F Leonetti, L Pisani, M Catto, A Carotti Molecules 23 (2), 250, 2018 | 600 | 2018 |
Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase C Brühlmann, F Ooms, PA Carrupt, B Testa, M Catto, F Leonetti, ... Journal of Medicinal Chemistry 44 (19), 3195-3198, 2001 | 412 | 2001 |
Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs C Gnerre, M Catto, F Leonetti, P Weber, PA Carrupt, C Altomare, A Carotti, ... Journal of medicinal chemistry 43 (25), 4747-4758, 2000 | 325 | 2000 |
Applicability domain for QSAR models: where theory meets reality D Gadaleta, GF Mangiatordi, M Catto, A Carotti, O Nicolotti International journal of quantitative structure-property relationships …, 2016 | 308 | 2016 |
Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening L Novaroli, M Reist, E Favre, A Carotti, M Catto, PA Carrupt Bioorganic & medicinal chemistry 13 (22), 6212-6217, 2005 | 162 | 2005 |
Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand-and target-based approaches M Catto, O Nicolotti, F Leonetti, A Carotti, AD Favia, R Soto-Otero, ... Journal of medicinal chemistry 49 (16), 4912-4925, 2006 | 133 | 2006 |
9, 10‐Anthraquinone hinders β‐aggregation: How does a small molecule interfere with Aβ‐peptide amyloid fibrillation? M Convertino, R Pellarin, M Catto, A Carotti, A Caflisch Protein Science 18 (4), 792-800, 2009 | 125 | 2009 |
Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl) oxy]-4-[(methylamino) methyl … L Pisani, G Muncipinto, TF Miscioscia, O Nicolotti, F Leonetti, M Catto, ... Journal of medicinal chemistry 52 (21), 6685-6706, 2009 | 124 | 2009 |
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase M Catto, L Pisani, F Leonetti, O Nicolotti, P Pesce, A Stefanachi, ... Bioorganic & medicinal chemistry 21 (1), 146-152, 2013 | 111 | 2013 |
Design, synthesis, and biological evaluation of imidazolyl derivatives of 4, 7-disubstituted coumarins as aromatase inhibitors selective over 17-α-hydroxylase/C17− 20 lyase A Stefanachi, AD Favia, O Nicolotti, F Leonetti, L Pisani, M Catto, ... Journal of medicinal chemistry 54 (6), 1613-1625, 2011 | 106 | 2011 |
Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases L Pisani, M Catto, F Leonetti, O Nicolotti, A Stefanachi, F Campagna, ... Current medicinal chemistry 18 (30), 4568-4587, 2011 | 105 | 2011 |
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases R Farina, L Pisani, M Catto, O Nicolotti, D Gadaleta, N Denora, ... Journal of medicinal chemistry 58 (14), 5561-5578, 2015 | 104 | 2015 |
Impact of species-dependent differences on screening, design, and development of MAO B inhibitors L Novaroli, A Daina, E Favre, J Bravo, A Carotti, F Leonetti, M Catto, ... Journal of medicinal chemistry 49 (21), 6264-6272, 2006 | 103 | 2006 |
Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure− activity relationships C Altomare, S Cellamare, L Summo, M Catto, A Carotti, U Thull, ... Journal of medicinal chemistry 41 (20), 3812-3820, 1998 | 100 | 1998 |
Quinolizidinyl derivatives of bi-and tricyclic systems as potent inhibitors of acetyl-and butyrylcholinesterase with potential in Alzheimer’s disease B Tasso, M Catto, O Nicolotti, F Novelli, M Tonelli, I Giangreco, L Pisani, ... European Journal of Medicinal Chemistry 46 (6), 2170-2184, 2011 | 94 | 2011 |
Exploring basic tail modifications of coumarin-based dual acetylcholinesterase-monoamine oxidase B inhibitors: Identification of water-soluble, brain-permeant neuroprotective … L Pisani, R Farina, M Catto, RM Iacobazzi, O Nicolotti, S Cellamare, ... Journal of Medicinal Chemistry 59 (14), 6791-6806, 2016 | 91 | 2016 |
Inactivation of the glutamine/amino acid transporter ASCT2 by 1, 2, 3-dithiazoles: proteoliposomes as a tool to gain insights in the molecular mechanism of action and of … F Oppedisano, M Catto, PA Koutentis, O Nicolotti, L Pochini, M Koyioni, ... Toxicology and applied pharmacology 265 (1), 93-102, 2012 | 85 | 2012 |
Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1, 3-diones and indol-2-aryldiazenylmethylene-3-ones as β-amyloid aggregation inhibitors M Catto, R Aliano, A Carotti, S Cellamare, F Palluotto, R Purgatorio, ... European Journal of Medicinal Chemistry 45 (4), 1359-1366, 2010 | 83 | 2010 |
Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium‐like fragment as highly potent and selective dual binding site … L Pisani, M Catto, I Giangreco, F Leonetti, O Nicolotti, A Stefanachi, ... ChemMedChem 5 (9), 1616-1630, 2010 | 78 | 2010 |
Homo-and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors F Leonetti, M Catto, O Nicolotti, L Pisani, A Cappa, A Stefanachi, A Carotti Bioorganic & Medicinal Chemistry 16 (15), 7450-7456, 2008 | 75 | 2008 |