Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor A Vannini, C Volpari, G Filocamo, EC Casavola, M Brunetti, D Renzoni, ... Proceedings of the National Academy of Sciences 101 (42), 15064-15069, 2004 | 805 | 2004 |
HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics P Gallinari, SD Marco, P Jones, M Pallaoro, C Steinkühler Cell research 17 (3), 195-211, 2007 | 754 | 2007 |
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells F Palombo, P Gallinari, I Iaccarino, T Lettieri, M Hughes, A D'Arrigo, ... Science 268 (5219), 1912-1914, 1995 | 646 | 1995 |
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases A Lahm, C Paolini, M Pallaoro, MC Nardi, P Jones, P Neddermann, ... Proceedings of the National Academy of Sciences 104 (44), 17335-17340, 2007 | 640 | 2007 |
Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation G Canettieri, L Di Marcotullio, A Greco, S Coni, L Antonucci, P Infante, ... Nature cell biology 12 (2), 132-142, 2010 | 390 | 2010 |
Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors GC Minetti, C Colussi, R Adami, C Serra, C Mozzetta, V Parente, S Fortuni, ... Nature medicine 12 (10), 1147-1150, 2006 | 381 | 2006 |
Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain MJ Bottomley, PL Surdo, P Di Giovine, A Cirillo, R Scarpelli, F Ferrigno, ... Journal of Biological Chemistry 283 (39), 26694-26704, 2008 | 379 | 2008 |
Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase P Neddermann, P Gallinari, T Lettieri, D Schmid, O Truong, JJ Hsuan, ... Journal of Biological Chemistry 271 (22), 12767-12774, 1996 | 331 | 1996 |
Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex A Vannini, C Volpari, P Gallinari, P Jones, M Mattu, A Carfí, ... EMBO reports 8 (9), 879-884, 2007 | 305 | 2007 |
Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1 TR Waters, P Gallinari, J Jiricny, PF Swann Journal of Biological Chemistry 274 (1), 67-74, 1999 | 303 | 1999 |
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment C Colussi, C Mozzetta, A Gurtner, B Illi, J Rosati, S Straino, G Ragone, ... Proceedings of the National Academy of Sciences 105 (49), 19183-19187, 2008 | 283 | 2008 |
A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase P Gallinari, J Jiricny Nature 383 (6602), 735-738, 1996 | 265 | 1996 |
Multiple enzymatic activities associated with recombinant NS3 protein of hepatitis C virus P Gallinari, D Brennan, C Nardi, M Brunetti, L Tomei, C Steinkühler, ... Journal of virology 72 (8), 6758-6769, 1998 | 261 | 1998 |
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure P Gallo, MVG Latronico, P Gallo, S Grimaldi, F Borgia, M Todaro, P Jones, ... Cardiovascular research 80 (3), 416-424, 2008 | 185 | 2008 |
PP2A regulates HDAC4 nuclear import G Paroni, N Cernotta, C Dello Russo, P Gallinari, M Pallaoro, C Foti, ... Molecular biology of the cell 19 (2), 655-667, 2008 | 149 | 2008 |
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling B Illi, CD Russo, C Colussi, J Rosati, M Pallaoro, F Spallotta, D Rotili, ... Circulation research 102 (1), 51-58, 2008 | 133 | 2008 |
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases P Jones, S Altamura, R De Francesco, P Gallinari, A Lahm, ... Bioorganic & medicinal chemistry letters 18 (6), 1814-1819, 2008 | 124 | 2008 |
Molecular insights into azumamide E histone deacetylases inhibitory activity N Maulucci, MG Chini, S Di Micco, I Izzo, E Cafaro, A Russo, P Gallinari, ... Journal of the American Chemical Society 129 (10), 3007-3012, 2007 | 113 | 2007 |
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells D Rotili, D Tarantino, A Nebbioso, C Paolini, C Huidobro, E Lara, P Mellini, ... Journal of medicinal chemistry 55 (24), 10937-10947, 2012 | 104 | 2012 |
Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element P Gallinari, F La Bella, N Heintz Molecular and cellular biology 9 (4), 1566-1575, 1989 | 100 | 1989 |