| Quantitative reactivity profiling predicts functional cysteines in proteomes E Weerapana, C Wang, GM Simon, F Richter, S Khare, MBD Dillon, ... Nature 468 (7325), 790-795, 2010 | 1707 | 2010 |
| A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol JL Blankman, GM Simon, BF Cravatt Chemistry & biology 14 (12), 1347-1356, 2007 | 1391 | 2007 |
| The biological impact of mass-spectrometry-based proteomics BF Cravatt, GM Simon, JR Yates Iii Nature 450 (7172), 991-1000, 2007 | 890 | 2007 |
| Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for α/β-hydrolase 4 in this pathway GM Simon, BF Cravatt Journal of Biological Chemistry 281 (36), 26465-26472, 2006 | 450 | 2006 |
| Inactivation of N-Acyl Phosphatidylethanolamine Phospholipase D Reveals Multiple Mechanisms for the Biosynthesis of Endocannabinoids D Leung, A Saghatelian, GM Simon, BF Cravatt Biochemistry 45 (15), 4720-4726, 2006 | 439 | 2006 |
| Global mapping of the topography and magnitude of proteolytic events in apoptosis MM Dix, GM Simon, BF Cravatt Cell 134 (4), 679-691, 2008 | 409 | 2008 |
| Bacteria from diverse habitats colonize and compete in the mouse gut H Seedorf, NW Griffin, VK Ridaura, A Reyes, J Cheng, FE Rey, MI Smith, ... Cell 159 (2), 253-266, 2014 | 387 | 2014 |
| Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study GM Simon, BF Cravatt Journal of Biological Chemistry 285 (15), 11051-11055, 2010 | 374 | 2010 |
| Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening DA Bachovchin, T Ji, W Li, GM Simon, JL Blankman, A Adibekian, ... Proceedings of the National Academy of Sciences 107 (49), 20941-20946, 2010 | 321 | 2010 |
| Disparate proteome reactivity profiles of carbon electrophiles E Weerapana, GM Simon, BF Cravatt Nature chemical biology 4 (7), 405-407, 2008 | 290 | 2008 |
| Determining target engagement in living systems GM Simon, MJ Niphakis, BF Cravatt Nature chemical biology 9 (4), 200-205, 2013 | 279 | 2013 |
| Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain GM Simon, BF Cravatt Journal of Biological Chemistry 283 (14), 9341-9349, 2008 | 275 | 2008 |
| An activity-guided map of electrophile-cysteine interactions in primary human T cells EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ... Cell 182 (4), 1009-1026. e29, 2020 | 267 | 2020 |
| The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex DE Sterner, X Wang, MH Bloom, GM Simon, SL Berger Journal of Biological Chemistry 277 (10), 8178-8186, 2002 | 164 | 2002 |
| Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo GM Simon, BF Cravatt Molecular BioSystems 6 (8), 1411-1418, 2010 | 151 | 2010 |
| Functional interplay between caspase cleavage and phosphorylation sculpts the apoptotic proteome MM Dix, GM Simon, C Wang, E Okerberg, MP Patricelli, BF Cravatt Cell 150 (2), 426-440, 2012 | 148 | 2012 |
| Localization of N‐acyl phosphatidylethanolamine phospholipase D (NAPE‐PLD) expression in mouse brain: A new perspective on N‐acylethanolamines as neural signaling molecules M Egertová, GM Simon, BF Cravatt, MR Elphick Journal of Comparative Neurology 506 (4), 604-615, 2008 | 148 | 2008 |
| Biomarkers of endocannabinoid system activation in severe obesity JC Sipe, TM Scott, S Murray, O Harismendy, GM Simon, BF Cravatt, ... PloS one 5 (1), e8792, 2010 | 138 | 2010 |
| Identification of ABX-1431, a selective inhibitor of monoacylglycerol lipase and clinical candidate for treatment of neurological disorders JS Cisar, OD Weber, JR Clapper, JL Blankman, CL Henry, GM Simon, ... Journal of medicinal chemistry 61 (20), 9062-9084, 2018 | 137 | 2018 |
| DCAF11 supports targeted protein degradation by electrophilic proteolysis-targeting chimeras X Zhang, LM Luukkonen, CL Eissler, VM Crowley, Y Yamashita, ... Journal of the American Chemical Society 143 (13), 5141-5149, 2021 | 136 | 2021 |
Benjamin CravattProfessor of Chemistry, The Scripps Research InstituteVerified email at scripps.edu