| Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells CSH Tan, KD Go, X Bisteau, L Dai, CH Yong, N Prabhu, MB Ozturk, ... Science 359 (6380), 1170-1177, 2018 | 216 | 2018 |
| Modulation of protein-interaction states through the cell cycle L Dai, T Zhao, X Bisteau, W Sun, N Prabhu, YT Lim, RM Sobota, P Kaldis, ... Cell 173 (6), 1481-1494. e13, 2018 | 146 | 2018 |
| p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway M Farhang Ghahremani, S Goossens, D Nittner, X Bisteau, S Bartunkova, ... Cell Death & Differentiation 20 (7), 888-897, 2013 | 122 | 2013 |
| Rb inactivation in cell cycle and cancer: the puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase S Paternot, L Bockstaele, X Bisteau, H Kooken, K Coulonval, P Roger Cell cycle 9 (4), 689-699, 2010 | 121 | 2010 |
| The complex relationship between liver cancer and the cell cycle: a story of multiple regulations X Bisteau, MJ Caldez, P Kaldis Cancers 6 (1), 79-111, 2014 | 104 | 2014 |
| Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation L Bockstaele, X Bisteau, S Paternot, PP Roger Molecular and cellular biology 29 (15), 4188-4200, 2009 | 86 | 2009 |
| A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity AM Heijink, VA Blomen, X Bisteau, F Degener, FY Matsushita, P Kaldis, ... Proceedings of the National Academy of Sciences 112 (49), 15160-15165, 2015 | 72 | 2015 |
| CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point X Bisteau, S Paternot, B Colleoni, K Ecker, K Coulonval, P De Groote, ... PLoS genetics 9 (5), e1003546, 2013 | 70 | 2013 |
| Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality R Szmyd, J Niska-Blakie, MK Diril, P Renck Nunes, K Tzelepis, A Lacroix, ... Oncogene 38 (7), 998-1018, 2019 | 66 | 2019 |
| Loss of cyclin-dependent kinase 2 in the pancreas links primary β-cell dysfunction to progressive depletion of β-cell mass and diabetes SY Kim, JH Lee, MJ Merrins, O Gavrilova, X Bisteau, P Kaldis, LS Satin, ... Journal of Biological Chemistry 292 (9), 3841-3853, 2017 | 48 | 2017 |
| The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes S Paternot, B Colleoni, X Bisteau, PP Roger Cell cycle 13 (18), 2879-2888, 2014 | 48 | 2014 |
| Loss of the Greatwall kinase weakens the spindle assembly checkpoint MK Diril, X Bisteau, M Kitagawa, MJ Caldez, S Wee, J Gunaratne, SH Lee, ... PLoS genetics 12 (9), e1006310, 2016 | 43 | 2016 |
| Loss of hepatocyte cell division leads to liver inflammation and fibrosis PK Matthew R Dewhurst, Jin Rong Ow, Gözde Zafer, Noémi K M van Hul, Heike ... PLoS Genetics, e1009084, 2020 | 38 | 2020 |
| CDK10 mutations in humans and mice cause severe growth retardation, spine malformations, and developmental delays C Windpassinger, J Piard, C Bonnard, M Alfadhel, S Lim, X Bisteau, ... The American Journal of Human Genetics 101 (3), 391-403, 2017 | 35 | 2017 |
| Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress SR Jayapal, CQ Wang, X Bisteau, MJ Caldez, S Lim, V Tergaonkar, ... Haematologica 100 (4), 431, 2015 | 35 | 2015 |
| Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody M Rovira, M Miserocchi, A Montanari, L Hammou, L Chomette, J Pozo, ... Developmental Dynamics 252 (3), 400-414, 2023 | 31 | 2023 |
| JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21 B Colleoni, S Paternot, JM Pita, X Bisteau, K Coulonval, RJ Davis, ... Oncogene 36 (30), 4349-4361, 2017 | 30 | 2017 |
| Cdk2 catalytic activity is essential for meiotic cell division in vivo S Chauhan, MK Diril, JHS Lee, X Bisteau, V Manoharan, D Adhikari, ... Biochemical Journal 473 (18), 2783-2798, 2016 | 30 | 2016 |
| PER2 circadian oscillation sensitizes esophageal cancer cells to chemotherapy JA Redondo, R Bibes, A Vercauteren Drubbel, B Dassy, X Bisteau, ... Biology 10 (4), 266, 2021 | 19 | 2021 |
| The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis X Bisteau, J Lee, V Srinivas, JHS Lee, J Niska-Blakie, G Tan, SYX Yap, ... Oncogene 39 (44), 6816-6840, 2020 | 16 | 2020 |
Philipp KaldisLund University, Department of Clinical Sciences, Clinical Research Centre (CRC), Sweden and LundVerified email at med.lu.se