Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging RD Bell, EA Winkler, AP Sagare, I Singh, B LaRue, R Deane, BV Zlokovic Neuron 68 (3), 409-427, 2010 | 1614 | 2010 |
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A RD Bell, EA Winkler, I Singh, AP Sagare, R Deane, Z Wu, DM Holtzman, ... Nature 485 (7399), 512-516, 2012 | 1374 | 2012 |
Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury JJ Iliff, MJ Chen, BA Plog, DM Zeppenfeld, M Soltero, L Yang, I Singh, ... Journal of Neuroscience 34 (49), 16180-16193, 2014 | 1082 | 2014 |
A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease R Deane, I Singh, AP Sagare, RD Bell, NT Ross, B LaRue, R Love, ... The Journal of clinical investigation 122 (4), 1377-1392, 2012 | 710 | 2012 |
SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells RD Bell, R Deane, N Chow, X Long, A Sagare, I Singh, JW Streb, H Guo, ... Nature cell biology 11 (2), 143-153, 2009 | 317 | 2009 |
Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance I Singh, AP Sagare, M Coma, D Perlmutter, R Gelein, RD Bell, RJ Deane, ... Proceedings of the National Academy of Sciences 110 (36), 14771-14776, 2013 | 290 | 2013 |
Gαq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin I Singh, N Knezevic, GU Ahmmed, V Kini, AB Malik, D Mehta Journal of Biological Chemistry 282 (11), 7833-7843, 2007 | 255 | 2007 |
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells Z Zhong, H Ilieva, L Hallagan, R Bell, I Singh, N Paquette, M Thiyagarajan, ... The Journal of clinical investigation 119 (11), 3437-3449, 2009 | 198 | 2009 |
Production of Yersinia stable toxin (YST) and distribution of yst genes in biotype 1A strains of Yersinia enterocolitica I Singh, JS Virdi Journal of Medical Microbiology 53 (11), 1065-1068, 2004 | 159 | 2004 |
Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice BH Han, M Zhou, AW Johnson, I Singh, F Liao, AK Vellimana, JW Nelson, ... Proceedings of the National Academy of Sciences 112 (8), E881-E890, 2015 | 154 | 2015 |
Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor D Zhu, Y Wang, I Singh, RD Bell, R Deane, Z Zhong, A Sagare, ... Blood, The Journal of the American Society of Hematology 115 (23), 4963-4972, 2010 | 139 | 2010 |
RETRACTED: Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity H Guo, I Singh, Y Wang, R Deane, T Barrett, JA Fernández, N Chow, ... European Journal of Neuroscience 29 (6), 1119-1130, 2009 | 104 | 2009 |
Vitamin K–dependent protein S: beyond the protein C pathway B Dahlbäck Seminars in thrombosis and hemostasis 44 (02), 176-184, 2018 | 99 | 2018 |
Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity Y Wang, M Thiyagarajan, N Chow, I Singh, H Guo, TP Davis, BV Zlokovic Stroke 40 (5), 1864-1869, 2009 | 60 | 2009 |
A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain AP Sagare, RD Bell, A Srivastava, JD Sengillo, I Singh, Y Nishida, ... Journal of Biological Chemistry 288 (21), 15154-15166, 2013 | 48 | 2013 |
Isolation and characterization of Yersinia enterocolitica from diarrhoeic human subjects and other sources I Singh, S Bhatnagar, JS Virdi Current science, 1353-1355, 2003 | 48 | 2003 |
Interaction of Yersinia enterocolitica biotype 1A strains of diverse origin with cultured cells in vitro I Singh, JS Virdi Japanese journal of infectious diseases 58 (1), 31-33, 2005 | 46 | 2005 |
Species‐dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity H Guo, Y Wang, I Singh, D Liu, JA Fernández, JH Griffin, N Chow, ... Journal of neurochemistry 109 (1), 116-124, 2009 | 37 | 2009 |
STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks J Mehla, I Singh, D Diwan, JW Nelson, M Lawrence, E Lee, AQ Bauer, ... Acta Neuropathologica Communications 9, 1-19, 2021 | 31 | 2021 |
Minocycline protects against delayed cerebral ischemia after subarachnoid hemorrhage via matrix metalloproteinase‐9 inhibition AK Vellimana, ML Zhou, I Singh, DJ Aum, JW Nelson, GR Harris, ... Annals of Clinical and Translational Neurology 4 (12), 865-876, 2017 | 28 | 2017 |