A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage TT Paull, EP Rogakou, V Yamazaki, CU Kirchgessner, M Gellert, ... Current Biology 10 (15), 886-895, 2000 | 2748 | 2000 |
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex JH Lee, TT Paull Science 308 (5721), 551-554, 2005 | 1927 | 2005 |
ATM activation by oxidative stress Z Guo, S Kozlov, MF Lavin, MD Person, TT Paull Science 330 (6003), 517-521, 2010 | 1224 | 2010 |
The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks TT Paull, M Gellert Molecular cell 1 (7), 969-979, 1998 | 1216 | 1998 |
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex JH Lee, TT Paull Science 304 (5667), 93-96, 2004 | 977 | 2004 |
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals Z Lou, K Minter-Dykhouse, S Franco, M Gostissa, MA Rivera, A Celeste, ... Molecular cell 21 (2), 187-200, 2006 | 849 | 2006 |
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex TT Paull, M Gellert Genes & development 13 (10), 1276-1288, 1999 | 745 | 1999 |
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks JH Lee, TT Paull Oncogene 26 (56), 7741-7748, 2007 | 711 | 2007 |
Mechanisms of ATM activation TT Paull Annual review of biochemistry 84 (1), 711-738, 2015 | 554 | 2015 |
A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex A Dupré, L Boyer-Chatenet, RM Sattler, AP Modi, JH Lee, ML Nicolette, ... Nature chemical biology 4 (2), 119-125, 2008 | 466 | 2008 |
ATM functions at the peroxisome to induce pexophagy in response to ROS J Zhang, DN Tripathi, J Jing, A Alexander, J Kim, RT Powell, R Dere, ... Nature cell biology 17 (10), 1259-1269, 2015 | 443 | 2015 |
The nonspecific DNA-binding and-bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures. TT Paull, MJ Haykinson, RC Johnson Genes & development 7 (8), 1521-1534, 1993 | 413 | 1993 |
The ATM protein kinase and cellular redox signaling: beyond the DNA damage response S Ditch, TT Paull Trends in biochemical sciences 37 (1), 15-22, 2012 | 378 | 2012 |
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex BM Lengsfeld, AJ Rattray, V Bhaskara, R Ghirlando, TT Paull Molecular cell 28 (4), 638-651, 2007 | 351 | 2007 |
Direct DNA binding by Brca1 TT Paull, D Cortez, B Bowers, SJ Elledge, M Gellert Proceedings of the National Academy of Sciences 98 (11), 6086-6091, 2001 | 343 | 2001 |
Stimulation of V (D) J cleavage by high mobility group proteins DC van Gent, K Hiom, TT Paull, M Gellert The EMBO journal, 1997 | 325 | 1997 |
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks EY Shim, WH Chung, ML Nicolette, Y Zhang, M Davis, Z Zhu, TT Paull, ... The EMBO journal 29 (19), 3370-3380, 2010 | 300 | 2010 |
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ... Nature 453 (7195), 677-681, 2008 | 290 | 2008 |
Involvement of human MOF in ATM function A Gupta, GG Sharma, CSH Young, M Agarwal, ER Smith, TT Paull, ... Molecular and cellular biology, 2005 | 286 | 2005 |
Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks ML Nicolette, K Lee, Z Guo, M Rani, JM Chow, SE Lee, TT Paull Nature structural & molecular biology 17 (12), 1478-1485, 2010 | 283 | 2010 |