| BET inhibitor resistance emerges from leukaemia stem cells CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ... Nature 525 (7570), 538-542, 2015 | 543 | 2015 |
| MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ... Genome biology 20, 1-11, 2019 | 223 | 2019 |
| A statistical framework for analyzing deep mutational scanning data AF Rubin, H Gelman, N Lucas, SM Bajjalieh, AT Papenfuss, TP Speed, ... Genome biology 18, 1-15, 2017 | 217 | 2017 |
| GA4GH: International policies and standards for data sharing across genomic research and healthcare HL Rehm, AJH Page, L Smith, JB Adams, G Alterovitz, LJ Babb, ... Cell genomics 1 (2), 2021 | 191 | 2021 |
| Comment on "The consensus coding sequences of human breast and colorectal cancers" AF Rubin, P Green Science 317 (5844), 1500, 2007 | 172 | 2007 |
| Mutation patterns in cancer genomes AF Rubin, P Green Proceedings of the National Academy of Sciences 106 (51), 21766-21770, 2009 | 103 | 2009 |
| Closing the gap: Systematic integration of multiplexed functional data resolves variants of uncertain significance in BRCA1, TP53, and PTEN S Fayer, C Horton, JN Dines, AF Rubin, ME Richardson, K McGoldrick, ... The American Journal of Human Genetics 108 (12), 2248-2258, 2021 | 84 | 2021 |
| A combined approach reveals a regulatory mechanism coupling Src’s kinase activity, localization, and phosphotransferase-independent functions E Ahler, AC Register, S Chakraborty, L Fang, EM Dieter, KA Sitko, ... Molecular cell 74 (2), 393-408. e20, 2019 | 71 | 2019 |
| An Atlas of Variant Effects to understand the genome at nucleotide resolution DM Fowler, DJ Adams, AL Gloyn, WC Hahn, DS Marks, LA Muffley, ... Genome Biology 24 (1), 147, 2023 | 61 | 2023 |
| Recommendations for the collection and use of multiplexed functional data for clinical variant interpretation H Gelman, JN Dines, J Berg, AH Berger, S Brnich, FM Hisama, RG James, ... Genome Medicine 11, 1-11, 2019 | 58 | 2019 |
| Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning JL Bridgford, SM Lee, CMM Lee, P Guglielmelli, E Rumi, D Pietra, ... Blood, The Journal of the American Society of Hematology 135 (4), 287-292, 2020 | 45 | 2020 |
| Collateral fitness effects of mutations JD Mehlhoff, FW Stearns, D Rohm, B Wang, EY Tsou, N Dutta, MH Hsiao, ... Proceedings of the National Academy of Sciences 117 (21), 11597-11607, 2020 | 43 | 2020 |
| Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii) AL Patchett, THH Coorens, J Darby, R Wilson, MJ McKay, KS Kamath, ... Cellular and Molecular Life Sciences 77, 1847-1858, 2020 | 36 | 2020 |
| Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae MS Rich, C Payen, AF Rubin, GT Ong, MR Sanchez, N Yachie, ... Genetics 203 (1), 191-202, 2016 | 34 | 2016 |
| MaveRegistry: a collaboration platform for multiplexed assays of variant effect D Kuang, J Weile, N Kishore, M Nguyen, AF Rubin, S Fields, DM Fowler, ... Bioinformatics 37 (19), 3382-3383, 2021 | 25 | 2021 |
| MaveDB v2: a curated community database with over three million variant effects from multiplexed functional assays AF Rubin, JK Min, NJ Rollins, EY Da, D Esposito, M Harrington, J Stone, ... Biorxiv, 2021.11. 29.470445, 2021 | 17 | 2021 |
| sccomp: Robust differential composition and variability analysis for single-cell data S Mangiola, AJ Roth-Schulze, M Trussart, E Zozaya-Valdés, M Ma, Z Gao, ... Proceedings of the National Academy of Sciences 120 (33), e2203828120, 2023 | 16 | 2023 |
| Human and viral membrane–associated E3 ubiquitin ligases MARCH1 and MIR2 recognize different features of CD86 to downregulate surface expression R Trenker, X Wu, JV Nguyen, S Wilcox, AF Rubin, ME Call, MJ Call Journal of Biological Chemistry 297 (1), 2021 | 10 | 2021 |
| Identifying new hybrid insulin peptides (HIPs) in type 1 diabetes SI Mannering, AF Rubin, R Wang, P Bhattacharjee Frontiers in Immunology 12, 667870, 2021 | 10 | 2021 |
| Expression-based segmentation of the Drosophila genome AF Rubin, P Green BMC genomics 14, 1-8, 2013 | 9 | 2013 |
