| A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases M Treiman, C Caspersen, SB Christensen Trends in pharmacological sciences 19 (4), 131-135, 1998 | 729 | 1998 |
| Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage O Thastrup, AP Dawson, O Scharff, B Foder, PJ Cullen, BK Drøbak, ... Agents and actions 27, 17-23, 1989 | 687* | 1989 |
| Antileishmanial chalcones: Statistical design, synthesis, and three-dimensional quantitative structure− activity relationship analysis SF Nielsen, SB Christensen, G Cruciani, A Kharazmi, T Liljefors Journal of Medicinal Chemistry 41 (24), 4819-4832, 1998 | 447 | 1998 |
| Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection M Chen, TG Theander, SB Christensen, L Hviid, LIN Zhai, A Kharazmi Antimicrobial agents and chemotherapy 38 (7), 1470-1475, 1994 | 369 | 1994 |
| Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer SR Denmeade, CM Jakobsen, S Janssen, SR Khan, ES Garrett, H Lilja, ... Journal of the National Cancer Institute 95 (13), 990-1000, 2003 | 359 | 2003 |
| Licochalcone A, a novel antiparasitic agent with potent activity against human pathogenic protozoan species of Leishmania M Chen, SB Christensen, J Blom, E Lemmich, L Nadelmann, K Fich, ... Antimicrobial agents and chemotherapy 37 (12), 2550-2556, 1993 | 303 | 1993 |
| An Antiinflammatory Galactolipid from Rose Hip (Rosa canina) that Inhibits Chemotaxis of Human Peripheral Blood Neutrophils in Vitro E Larsen, A Kharazmi, LP Christensen, SB Christensen Journal of Natural Products 66 (7), 994-995, 2003 | 302 | 2003 |
| New anti-HIV-1, antimalarial, and antifungal compounds from Terminalia bellerica R Valsaraj, P Pushpangadan, UW Smitt, A Adsersen, SB Christensen, ... Journal of natural products 60 (7), 739-742, 1997 | 282 | 1997 |
| Ancistrotanzanine C and Related 5,1‘- and 7,3‘-Coupled Naphthylisoquinoline Alkaloids from Ancistrocladus tanzaniensis G Bringmann, M Dreyer, JH Faber, PW Dalsgaard, D Stærk, ... Journal of natural products 67 (5), 743-748, 2004 | 277 | 2004 |
| Inhibition of Fumarate Reductase inLeishmania major and L. donovani by Chalcones M Chen, L Zhai, SB Christensen, TG Theander, A Kharazmi Antimicrobial agents and chemotherapy 45 (7), 2023-2029, 2001 | 268 | 2001 |
| The antileishmanial activity of novel oxygenated chalcones and their mechanism of action L Zhai, M Chen, J Blom, TG Theander, SB Christensen, A Kharazmi Journal of antimicrobial chemotherapy 43 (6), 793-803, 1999 | 261 | 1999 |
| Are we ready for back-to-nature crop breeding? MG Palmgren, AK Edenbrandt, SE Vedel, MM Andersen, X Landes, ... Trends in plant science 20 (3), 155-164, 2015 | 260 | 2015 |
| Engineering a prostate-specific membrane antigen–activated tumor endothelial cell prodrug for cancer therapy SR Denmeade, AM Mhaka, DM Rosen, WN Brennen, S Dalrymple, I Dach, ... Science translational medicine 4 (140), 140ra86-140ra86, 2012 | 256 | 2012 |
| A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa HB Rasmussen, SB Christensen, LP Kvist, A Karazmi Planta medica 66 (04), 396-398, 2000 | 250 | 2000 |
| Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response P Sehgal, P Szalai, C Olesen, HA Praetorius, P Nissen, SB Christensen, ... Journal of Biological Chemistry 292 (48), 19656-19673, 2017 | 241 | 2017 |
| Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis LP Kvist, SB Christensen, HB Rasmussen, K Mejia, A Gonzalez Journal of ethnopharmacology 106 (3), 390-402, 2006 | 193 | 2006 |
| Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea K Hansen, A Adsersen, SB Christensen, SR Jensen, U Nyman, UW Smitt Phytomedicine 2 (4), 319-325, 1996 | 191 | 1996 |
| The explosion of structural information on insect neuropeptides A Andersen, SB Christensen, D Deepak, G Gäde, A Khare, UW Smitt, ... Fortschritte der Chemie organischer Naturstoffe/Progress in the Chemistry of …, 1997 | 189 | 1997 |
| The novel oxygenated chalcone, 2, 4-dimethoxy-4'-butoxychalcone, exhibits potent activity against human malaria parasite Plasmodium falciparum in vitro and rodent parasites … M Chen, SB Christensen, L Zhai, MH Rasmussen, TG Theander, ... Journal of Infectious Diseases 176 (5), 1327-1333, 1997 | 187 | 1997 |
| Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani M Chen, SB Christensen, TG Theander, A Kharazmi Antimicrobial agents and chemotherapy 38 (6), 1339-1344, 1994 | 186 | 1994 |
john isaacsProfessor of OncologyVerified email at jhmi.edu