Therapeutic strategies for Alzheimer's disease in clinical trials J Godyń, J Jończyk, D Panek, B Malawska Pharmacological Reports 68 (1), 127-138, 2016 | 560 | 2016 |
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta … D Panek, A Więckowska, T Wichur, M Bajda, J Godyń, J Jończyk, K Mika, ... European journal of medicinal chemistry 125, 676-695, 2017 | 95 | 2017 |
Design and synthesis of new barbituric-and thiobarbituric acid derivatives as potent urease inhibitors: Structure activity relationship and molecular modeling studies A Rauf, S Shahzad, M Bajda, M Yar, F Ahmed, N Hussain, MN Akhtar, ... Bioorganic & Medicinal Chemistry 23 (17), 6049-6058, 2015 | 66 | 2015 |
Novel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studies S Mutahir, J Jończyk, M Bajda, IU Khan, MA Khan, N Ullah, M Ashraf, ... Bioorganic chemistry 64, 13-20, 2016 | 64 | 2016 |
1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer’s disease T Wichur, A Więckowska, K Więckowski, J Godyń, J Jończyk, ... European Journal of Medicinal Chemistry 187, 111916, 2020 | 54 | 2020 |
Design, synthesis, and biological evaluation of 1-benzylamino-2-hydroxyalkyl derivatives as new potential disease-modifying multifunctional anti-Alzheimer’s agents D Panek, A Wieckowska, J Jonczyk, J Godyn, M Bajda, T Wichur, ... ACS Chemical Neuroscience 9 (5), 1074-1094, 2018 | 50 | 2018 |
γ-Aminobutyric acid transporters as relevant biological target: Their function, structure, inhibitors and role in the therapy of different diseases K Łątka, J Jończyk, M Bajda International journal of biological macromolecules 158, 750-772, 2020 | 40 | 2020 |
Design, synthesis, and biological evaluation of 2-(benzylamino-2-hydroxyalkyl) isoindoline-1, 3-diones derivatives as potential disease-modifying multifunctional anti-Alzheimer … D Panek, A Więckowska, A Pasieka, J Godyń, J Jończyk, M Bajda, D Knez, ... Molecules 23 (2), 347, 2018 | 40 | 2018 |
Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease M Bajda, J Jończyk, B Malawska, K Czarnecka, M Girek, P Olszewska, ... Bioorganic & Medicinal Chemistry 23 (17), 5610-5618, 2015 | 35 | 2015 |
Dual‐Acting Diether Derivatives of Piperidine and Homopiperidine with Histamine H3 Receptor Antagonistic and Anticholinesterase Activity M Bajda, KJ Kuder, D Łażewska, K Kieć‐Kononowicz, A Więckowska, ... Archiv der Pharmazie 345 (8), 591-597, 2012 | 34 | 2012 |
Novel carbamate derivatives as selective butyrylcholinesterase inhibitors M Bajda, K Łątka, M Hebda, J Jończyk, B Malawska Bioorganic Chemistry 78, 29-38, 2018 | 28 | 2018 |
Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment K Czarnecka, N Chufarova, K Halczuk, K Maciejewska, M Girek, ... European journal of medicinal chemistry 145, 760-769, 2018 | 28 | 2018 |
Cholinesterase inhibitory activity of chlorophenoxy derivatives—Histamine H3 receptor ligands D Łażewska, J Jończyk, M Bajda, N Szałaj, A Więckowska, D Panek, ... Bioorganic & Medicinal Chemistry Letters 26 (16), 4140-4145, 2016 | 28 | 2016 |
Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification J Jończyk, B Malawska, M Bajda PLoS One 12 (10), e0186108, 2017 | 26 | 2017 |
New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer’s disease K Czarnecka, M Girek, K Maciejewska, R Skibiński, J Jończyk, M Bajda, ... Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 158-170, 2018 | 24 | 2018 |
Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines K Lodarski, J Jończyk, N Guzior, M Bajda, J Gładysz, J Walczyk, M Jeleń, ... Journal of Enzyme Inhibition and Medicinal Chemistry 30 (1), 98-106, 2015 | 22 | 2015 |
Application of Computational Methods for the Design of BACE-1 Inhibitors: Validation of in Silico Modelling M Bajda, J Jończyk, B Malawska, S Filipek International Journal of Molecular Sciences 15 (3), 5128-5139, 2014 | 22 | 2014 |
Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer’s disease treatment K Czarnecka, P Szymański, M Girek, E Mikiciuk-Olasik, R Skibiński, ... Bioorganic Chemistry 72, 315-322, 2017 | 21 | 2017 |
New tacrine analogs as acetylcholinesterase inhibitors—theoretical study with chemometric analysis P Szymański, R Skibiński, T Inglot, M Bajda, J Jończyk, B Malawska, ... Molecules 18 (3), 2878-2894, 2013 | 21 | 2013 |
Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters A Pasieka, D Panek, J Jończyk, J Godyń, N Szałaj, G Latacz, J Tabor, ... European Journal of Medicinal Chemistry 218, 113397, 2021 | 19 | 2021 |