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Jakub Jończyk
Jakub Jończyk
Other namesJakub Jonczyk, Jakub Józef Jończyk
Jagiellonian University Medical College; Sano Centre for Personalised Computational Medicine
Verified email at uj.edu.pl
Title
Cited by
Cited by
Year
Therapeutic strategies for Alzheimer's disease in clinical trials
J Godyń, J Jończyk, D Panek, B Malawska
Pharmacological Reports 68 (1), 127-138, 2016
5602016
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta …
D Panek, A Więckowska, T Wichur, M Bajda, J Godyń, J Jończyk, K Mika, ...
European journal of medicinal chemistry 125, 676-695, 2017
952017
Design and synthesis of new barbituric-and thiobarbituric acid derivatives as potent urease inhibitors: Structure activity relationship and molecular modeling studies
A Rauf, S Shahzad, M Bajda, M Yar, F Ahmed, N Hussain, MN Akhtar, ...
Bioorganic & Medicinal Chemistry 23 (17), 6049-6058, 2015
662015
Novel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studies
S Mutahir, J Jończyk, M Bajda, IU Khan, MA Khan, N Ullah, M Ashraf, ...
Bioorganic chemistry 64, 13-20, 2016
642016
1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer’s disease
T Wichur, A Więckowska, K Więckowski, J Godyń, J Jończyk, ...
European Journal of Medicinal Chemistry 187, 111916, 2020
542020
Design, synthesis, and biological evaluation of 1-benzylamino-2-hydroxyalkyl derivatives as new potential disease-modifying multifunctional anti-Alzheimer’s agents
D Panek, A Wieckowska, J Jonczyk, J Godyn, M Bajda, T Wichur, ...
ACS Chemical Neuroscience 9 (5), 1074-1094, 2018
502018
γ-Aminobutyric acid transporters as relevant biological target: Their function, structure, inhibitors and role in the therapy of different diseases
K Łątka, J Jończyk, M Bajda
International journal of biological macromolecules 158, 750-772, 2020
402020
Design, synthesis, and biological evaluation of 2-(benzylamino-2-hydroxyalkyl) isoindoline-1, 3-diones derivatives as potential disease-modifying multifunctional anti-Alzheimer …
D Panek, A Więckowska, A Pasieka, J Godyń, J Jończyk, M Bajda, D Knez, ...
Molecules 23 (2), 347, 2018
402018
Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease
M Bajda, J Jończyk, B Malawska, K Czarnecka, M Girek, P Olszewska, ...
Bioorganic & Medicinal Chemistry 23 (17), 5610-5618, 2015
352015
Dual‐Acting Diether Derivatives of Piperidine and Homopiperidine with Histamine H3 Receptor Antagonistic and Anticholinesterase Activity
M Bajda, KJ Kuder, D Łażewska, K Kieć‐Kononowicz, A Więckowska, ...
Archiv der Pharmazie 345 (8), 591-597, 2012
342012
Novel carbamate derivatives as selective butyrylcholinesterase inhibitors
M Bajda, K Łątka, M Hebda, J Jończyk, B Malawska
Bioorganic Chemistry 78, 29-38, 2018
282018
Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment
K Czarnecka, N Chufarova, K Halczuk, K Maciejewska, M Girek, ...
European journal of medicinal chemistry 145, 760-769, 2018
282018
Cholinesterase inhibitory activity of chlorophenoxy derivatives—Histamine H3 receptor ligands
D Łażewska, J Jończyk, M Bajda, N Szałaj, A Więckowska, D Panek, ...
Bioorganic & Medicinal Chemistry Letters 26 (16), 4140-4145, 2016
282016
Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification
J Jończyk, B Malawska, M Bajda
PLoS One 12 (10), e0186108, 2017
262017
New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer’s disease
K Czarnecka, M Girek, K Maciejewska, R Skibiński, J Jończyk, M Bajda, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 158-170, 2018
242018
Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines
K Lodarski, J Jończyk, N Guzior, M Bajda, J Gładysz, J Walczyk, M Jeleń, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 30 (1), 98-106, 2015
222015
Application of Computational Methods for the Design of BACE-1 Inhibitors: Validation of in Silico Modelling
M Bajda, J Jończyk, B Malawska, S Filipek
International Journal of Molecular Sciences 15 (3), 5128-5139, 2014
222014
Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer’s disease treatment
K Czarnecka, P Szymański, M Girek, E Mikiciuk-Olasik, R Skibiński, ...
Bioorganic Chemistry 72, 315-322, 2017
212017
New tacrine analogs as acetylcholinesterase inhibitors—theoretical study with chemometric analysis
P Szymański, R Skibiński, T Inglot, M Bajda, J Jończyk, B Malawska, ...
Molecules 18 (3), 2878-2894, 2013
212013
Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters
A Pasieka, D Panek, J Jończyk, J Godyń, N Szałaj, G Latacz, J Tabor, ...
European Journal of Medicinal Chemistry 218, 113397, 2021
192021
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