HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells H Yu, S Lu, K Gasior, D Singh, S Vazquez-Sanchez, O Tapia, D Toprani, ... Science 371 (6529), eabb4309, 2021 | 266 | 2021 |
A novel GRK2/HDAC6 interaction modulates cell spreading and motility V Lafarga, I Aymerich, O Tapia, F Mayor Jr, P Penela The EMBO journal 31 (4), 856-869, 2012 | 137 | 2012 |
TDP-43 localizes in mRNA transcription and processing sites in mammalian neurons I Casafont, R Bengoechea, O Tapia, MT Berciano, M Lafarga Journal of structural biology 167 (3), 235-241, 2009 | 105 | 2009 |
Cajal’s contribution to the knowledge of the neuronal cell nucleus M Lafarga, I Casafont, R Bengoechea, O Tapia, MT Berciano Chromosoma 118, 437-443, 2009 | 76 | 2009 |
Reorganization of Cajal bodies and nucleolar targeting of coilin in motor neurons of type I spinal muscular atrophy O Tapia, R Bengoechea, A Palanca, R Arteaga, JF Val-Bernal, ... Histochemistry and cell biology 137, 657-667, 2012 | 69 | 2012 |
Cajal bodies in neurons M Lafarga, O Tapia, AM Romero, MT Berciano RNA biology 14 (6), 712-725, 2017 | 66 | 2017 |
SUMO-1 transiently localizes to Cajal bodies in mammalian neurons J Navascues, R Bengoechea, O Tapia, I Casafont, MT Berciano, ... Journal of structural biology 163 (2), 137-146, 2008 | 52 | 2008 |
Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer O Aguilera, JM González-Sancho, S Zazo, R Rincon, AF Fernandez, ... Oncotarget 6 (8), 5903, 2015 | 51 | 2015 |
Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells LC Cheng, S Baboo, C Lindsay, L Brusman, S Martinez-Bartolomé, ... Nucleus 10 (1), 126-143, 2019 | 48 | 2019 |
Messages from the voices within: regulation of signaling by proteins of the nuclear lamina L Gerace, O Tapia Current opinion in cell biology 52, 14-21, 2018 | 47 | 2018 |
Nucleolar disruption ensures nuclear accumulation of p21 upon DNA damage N Abella, S Brun, M Calvo, O Tapia, JD Weber, MT Berciano, M Lafarga, ... Traffic 11 (6), 743-755, 2010 | 40 | 2010 |
ALS-derived fibroblasts exhibit reduced proliferation rate, cytoplasmic TDP-43 aggregation and a higher susceptibility to DNA damage J Riancho, D Castanedo-Vázquez, F Gil-Bea, O Tapia, J Arozamena, ... Journal of neurology 267, 1291-1299, 2020 | 39 | 2020 |
Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression G Ferrer-Mayorga, S Alvarez-Díaz, N Valle, J De Las Rivas, M Mendes, ... Journal of Biological Chemistry 290 (44), 26533-26548, 2015 | 39 | 2015 |
Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases O Tapia, LG Fong, MD Huber, SG Young, L Gerace PloS one 10 (3), e0116196, 2015 | 39 | 2015 |
Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus O Tapia, JO Narcís, J Riancho, O Tarabal, L Piedrafita, J Calderó, ... Neurobiology of Disease 108, 83-99, 2017 | 35 | 2017 |
Nucleolar targeting of coilin is regulated by its hypomethylation state O Tapia, R Bengoechea, MT Berciano, M Lafarga Chromosoma 119, 527-540, 2010 | 35 | 2010 |
The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis O Tapia, V Lafarga, R Bengoechea, A Palanca, M Lafarga, MT Berciano Journal of cell science 127 (5), 939-946, 2014 | 33 | 2014 |
Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility P Penela, V Lafarga, O Tapia, V Rivas, L Nogués, E Lucas, ... Science Signaling 5 (224), pt3-pt3, 2012 | 32 | 2012 |
MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis M del Carmen Lafita-Navarro, R Blanco, J Mata-Garrido, J Liaño-Pons, ... Oncotarget 7 (43), 69536, 2016 | 31 | 2016 |
Nuclear speckles are involved in nuclear aggregation of PABPN1 and in the pathophysiology of oculopharyngeal muscular dystrophy R Bengoechea, O Tapia, I Casafont, J Berciano, M Lafarga, MT Berciano Neurobiology of disease 46 (1), 118-129, 2012 | 30 | 2012 |