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Shinya Ito
Shinya Ito
Verified email at zmbh.uni-heidelberg.de
Title
Cited by
Cited by
Year
Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone
S Ito, K Nagata
Seminars in cell & developmental biology 62, 142-151, 2017
2412017
Interactome screening identifies the ER luminal chaperone Hsp47 as a regulator of the unfolded protein response transducer IRE1α
D Sepulveda, D Rojas-Rivera, DA Rodríguez, J Groenendyk, A Köhler, ...
Molecular cell 69 (2), 238-252. e7, 2018
1752018
Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease
S Ito, K Nagata
Journal of Biological Chemistry 294 (6), 2133-2141, 2019
1442019
Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules
Y Ishikawa, S Ito, K Nagata, LY Sakai, HP Bächinger
Proceedings of the National Academy of Sciences 113 (41), E6036-E6044, 2016
1402016
Deletion of the collagen-specific molecular chaperone Hsp47 causes endoplasmic reticulum stress-mediated apoptosis of hepatic stellate cells
K Kawasaki, R Ushioda, S Ito, K Ikeda, Y Masago, K Nagata
Journal of biological chemistry 290 (6), 3639-3646, 2015
962015
A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis
S Ito, K Ogawa, K Takeuchi, M Takagi, M Yoshida, T Hirokawa, ...
Journal of Biological Chemistry 292 (49), 20076-20085, 2017
622017
Quality control of procollagen in cells
S Ito, K Nagata
Annual Review of Biochemistry 90 (1), 631-658, 2021
322021
Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout
KK Fujii, Y Taga, T Sakai, S Ito, S Hattori, K Nagata, T Koide
Scientific reports 9 (1), 17433, 2019
222019
Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen
S Ito, K Nagata
Biochemical and biophysical research communications 469 (3), 437-442, 2016
172016
Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy
A Kitamura, Y Ishida, H Kubota, CG Pack, T Homma, S Ito, K Araki, ...
Biochemical and biophysical research communications 497 (1), 279-284, 2018
152018
A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction
S Ito, M Saito, M Yoshida, K Takeuchi, T Doi, K Nagata
Journal of Biological Chemistry 294 (44), 15962-15972, 2019
112019
Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment
S Ito, Y Araki, A Tanaka, J Igarashi, T Wada, T Shimizu
Journal of inorganic biochemistry 103 (7), 989-996, 2009
92009
Structure–activity relationship study on Col-003, a protein–protein interaction inhibitor between collagen and Hsp47
M Yoshida, M Saito, S Ito, K Ogawa, N Goshima, K Nagata, T Doi
Chemical and Pharmaceutical Bulletin 68 (3), 220-226, 2020
82020
The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis
S Ito, J Igarashi, T Shimizu
Journal of inorganic biochemistry 103 (10), 1380-1385, 2009
82009
HSP47 levels determine the degree of body adiposity
J Shin, S Toyoda, Y Okuno, R Hayashi, S Nishitani, T Onodera, ...
Nature communications 14 (1), 7319, 2023
42023
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