Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone S Ito, K Nagata Seminars in cell & developmental biology 62, 142-151, 2017 | 241 | 2017 |
Interactome screening identifies the ER luminal chaperone Hsp47 as a regulator of the unfolded protein response transducer IRE1α D Sepulveda, D Rojas-Rivera, DA Rodríguez, J Groenendyk, A Köhler, ... Molecular cell 69 (2), 238-252. e7, 2018 | 175 | 2018 |
Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease S Ito, K Nagata Journal of Biological Chemistry 294 (6), 2133-2141, 2019 | 144 | 2019 |
Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules Y Ishikawa, S Ito, K Nagata, LY Sakai, HP Bächinger Proceedings of the National Academy of Sciences 113 (41), E6036-E6044, 2016 | 140 | 2016 |
Deletion of the collagen-specific molecular chaperone Hsp47 causes endoplasmic reticulum stress-mediated apoptosis of hepatic stellate cells K Kawasaki, R Ushioda, S Ito, K Ikeda, Y Masago, K Nagata Journal of biological chemistry 290 (6), 3639-3646, 2015 | 96 | 2015 |
A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis S Ito, K Ogawa, K Takeuchi, M Takagi, M Yoshida, T Hirokawa, ... Journal of Biological Chemistry 292 (49), 20076-20085, 2017 | 62 | 2017 |
Quality control of procollagen in cells S Ito, K Nagata Annual Review of Biochemistry 90 (1), 631-658, 2021 | 32 | 2021 |
Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout KK Fujii, Y Taga, T Sakai, S Ito, S Hattori, K Nagata, T Koide Scientific reports 9 (1), 17433, 2019 | 22 | 2019 |
Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen S Ito, K Nagata Biochemical and biophysical research communications 469 (3), 437-442, 2016 | 17 | 2016 |
Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy A Kitamura, Y Ishida, H Kubota, CG Pack, T Homma, S Ito, K Araki, ... Biochemical and biophysical research communications 497 (1), 279-284, 2018 | 15 | 2018 |
A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction S Ito, M Saito, M Yoshida, K Takeuchi, T Doi, K Nagata Journal of Biological Chemistry 294 (44), 15962-15972, 2019 | 11 | 2019 |
Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment S Ito, Y Araki, A Tanaka, J Igarashi, T Wada, T Shimizu Journal of inorganic biochemistry 103 (7), 989-996, 2009 | 9 | 2009 |
Structure–activity relationship study on Col-003, a protein–protein interaction inhibitor between collagen and Hsp47 M Yoshida, M Saito, S Ito, K Ogawa, N Goshima, K Nagata, T Doi Chemical and Pharmaceutical Bulletin 68 (3), 220-226, 2020 | 8 | 2020 |
The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis S Ito, J Igarashi, T Shimizu Journal of inorganic biochemistry 103 (10), 1380-1385, 2009 | 8 | 2009 |
HSP47 levels determine the degree of body adiposity J Shin, S Toyoda, Y Okuno, R Hayashi, S Nishitani, T Onodera, ... Nature communications 14 (1), 7319, 2023 | 4 | 2023 |